We're hiring! Enjoyed @jackholcombe.bsky.social PhD Prize talk @edrc2025.bsky.social @fly-eds.bsky.social? We're recruiting a #postdoc to explore how cell biology is patterned in the #Drosophila renal system. Come join us for live-imaging, molecular cell biology and omics! Deadline 25th January.

Interested in how life history may shape the gut microbiome of a wild mammal? Keen on getting to work with an iconic long-term study system in Scotland? Check out this PhD opportunity with me, Josephine Pemberton and @gfalbery.bsky.social Reach out to chat more! www.findaphd.com/phds/project...

elifesciences.org/articles/102... I am very excited to share with you our publication building Deep3DSIM microscope using adaptive optic. It allows imaging into an intact fly brain >130 microns with high quality 3DSIM as well as remote focusing without moving the objective or specimen.

Our new study is out in Cell Reports! We show that the DNA repair pathway ATM-γH2Av is repurposed in the gut during infection, even without DNA breaks. Pathogens, not microbiota, trigger it via NOX to clear damaged cells and drive stem cell regeneration. www.cell.com/cell-reports...

Another preprint from @pankajd.bsky.social ! www.biorxiv.org/content/10.1...

Congratulations Domi Kwecka and @nishaphilip.bsky.social on their elegant work on the requirement for plasmodium CBP-O in crossing the mosquito midgut - it was fun to be involved! 🦟

Now proper out: doi.org/10.1093/gene...

Exciting new Ruta lab preprint by @annaryba.bsky.social et al. on the neural underpinnings of intraspecific behavioral variation: Strain variation identifies a neural substrate for behavioral evolution Drosophila www.biorxiv.org/content/10.1...

New from the Kinghorn Lab! 🧠🔬 Our latest preprint shows that in fly 🪰🧬 Gaucher’s & Parkinson’s 🧠 models, kidney dysfunction drives neurodegeneration - supporting emerging links between renal health & Parkinson's. You can read it here: www.biorxiv.org/content/10.1...

Our latest interview is with 2025 @bscb-official.bsky.social WICB early career medal winner Helen Weavers @helenweavers.bsky.social‬. We hear about what winning the award means to Helen, her research and her advice on staying resilient. journals.biologists.com/jcs/article/...

How does nutrient-responsive #mTORC1 sense the key amino acid #glutamine? Gianluca Figlia, Aurelio Teleman et al @telemanlab.bsky.social identify a combination of GCN2-dependent processes triggered by secondary depletion of asparagine in glutamine-starved cells www.embopress.org/doi/full/10....

I am very proud to present you the first paper from the main research line of my group at the @mpiage.bsky.social in collaboration with my current group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC, which is now published in @geroscience.bsky.social! link.springer.com/article/10.1...

New preprint - varied routes to ⬆️ infection susceptibility over age - via bona fide immunosenescence, but also often via reduced tolerance 🪰🕰️🦠☠️ ⬆️ risk to die from infection predicts lifespan in males. Great group effort from the lab! www.biorxiv.org/content/10.1...

🎉Excited to share our latest paper, published in Nature Communications!🎉 "Enhancing autophagy by redox regulation extends lifespan in Drosophila" #redox #metabolism #ageing #Drosophila @natcomms.nature.com @mrc-lms.bsky.social doi.org/10.1038/s414...

Next paper from @pankajd.bsky.social ! www.biorxiv.org/content/10.1...

It is difficult to interpret single #pathogen burden during #infection. It is hard to untangle default in resistance and tolerance to explain #susceptibility. We help making sense of with-host dynamics and give tools to study infection, especially in #Drosophila. elifesciences.org/articles/104...

In our last preprint we identify endogenous dsRNAs capable of activating the interferon response. Could these be relevant to our understanding of DiGeorge syndrome (22qDS)? In collaboration with @herassr.bsky.social and @heick.bsky.social labs www.biorxiv.org/content/10.1...

The final version of my lab’s recent paper on the role of estrogen related receptor in regulation of germline stem cells is now available in @devbiol.bsky.social. You can read the full text here: www.sciencedirect.com/science/arti...

Petra and Aidan are giving a public lecture on April 6th (THIS SUNDAY) at the Science Festival all about their public engagement program for which they won the Tam Dalyell prize for Excellence in Engaging the Public with Science :) www.edinburghscience.co.uk/event/tam-da...

“Bluesky has won”. Please retweet… 😉

I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.

My lab has a new preprint that is available! 🧵below. www.biorxiv.org/content/10.1...

📣📣 🦟 Wondering what the putative EPAC in Plasmodium does. See our new study characterising a cryptic cyclic nucleotide binding protein required for mosquito infection by the ookinete. Well done Domi Kwecka and team #ookinete #malaria www.biorxiv.org/content/10.1...

📢Job alert Are you interested in Drosophila genetics, insects, innate immunity, evolution? We are offering an exciting Group Leader position within the NetRNA consortium (labex-netrna.cnrs.fr/presentation...) See below for more information and do not hesitate to contact us.

The Royal Society's Newton International Fellowships will open for applications next week on 21 January. These fellowships are for non-UK early career scientists who wish to conduct research in the UK. Find out more on our website: #RSGrants royalsociety.org/grants/newto...

If you're looking for a PhD studentship, we have an exciting opportunity to study why some cells live longer than others. Results could help design better cell-based therapies. #EASTBIO #macrophages www.findaphd.com/phds/project...

Excited to see our new gut hormone paper in @naturecomms.bsky.social in collaboration with our alumnus Dr. Yuto Yoshinari (Gunma Univ.) and others! A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster. www.nature.com/articles/s41...

Looking forward to a fabulous European fly meeting in Alicante! #EDRC2025 #Drosophila 👇🏻👇🏻👇🏻

@nehaagrawal.bsky.social and I have an exciting EastBio PhD opportunity investigating the interplay between obesity and immune dysfunction, in beautiful Edinburgh. Deadline 17th January. Please share! www.findaphd.com/phds/project...

Applications are open for the Education Beyond Borders Postgraduate Scholarships at #edinburghuni for 2025/2026. Closing date is 3 February 2025. Find out more at the information session on 10 January. All details below: global.ed.ac.uk/education-be...

This PhD project, with Iris Mair Amy Pedersen and myself looks at the interactions between microbiota and immune regulatory cells and pathways at barrier sites. It includes fieldwork with wild mice on the Isle of May. www.findaphd.com/phds/project...

PhD studentship available with me to study immune signalling evolution. Deadline in 2 days! Project and application details here: mahansonresearch.weebly.com/blog/phd-stu...

Happy #FluorescenceFriday!