Our new study is out in Cell Reports! We show that the DNA repair pathway ATM-γH2Av is repurposed in the gut during infection, even without DNA breaks. Pathogens, not microbiota, trigger it via NOX to clear damaged cells and drive stem cell regeneration. www.cell.com/cell-reports...

The next paper from @pujabiswas.bsky.social PhD has been posted! www.biorxiv.org/content/10.1... Puja found a sex difference in levels of hormones produced by gut enteroendocrine cells.

Intense ivory poaching has led to the evolution of tusklessness in some African elephant populations, which might reduce poaching, but also happens to be an X-chromosome–linked dominant trait that is lethal to males #EleFunFactFriday #TheMoreYouKnow 💫 🧪 🐘 www.science.org/doi/10.1126/...

AOC: We should be clear about who Charlie Kirk was. A man who believed that the civil rights act that granted black Americans the right to vote was a mistake… His rhetoric and beliefs were ignorant, uneducated, and sought to disenfranchise millions of Americans.

Hello #Drosophila & #insect people! I am searching for libraries of ORF/RNA from Tribolium castaneum and Bombyx mori for cloning cDNA/proteins (or insects with unusual body plans). Is there an existing resource centre where I can find them, please? Thanks very much in advance for your help!

Hey #Drosophila community: who has already some experience with these new procedures which may also affect normal mail? Please, be so kind to share your knowledge, tips & tricks! @bdsc.bsky.social @fly-eds.bsky.social @flybase.bsky.social - urldefense.com/v3/__https:/...

NEW: The anti-Trump protest happening right now on the streets of Washington DC is HUGE! It looks like tens of thousands have joined. This is the view from 16th Street - people stretching as far as the eye can see 👏

40%-60% of colon cancer biopsies are positive for a TP53 mutation, and people with Li-Fraumeni syndrome (LFS) (germline TP53 mux) have a 75-100% lifetime chance of a cancer diagnosis.

Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!

No brush, no pencil. Just a typewriter. Artist James, using a 1930s Smith Premier typewriter, typed out this painting. #art #printer #unique #typewriter #illustration

We are recruiting‼️A permanent university lecturer position in BIOSTATISTICS is available at @helsinki.fi Faculty of Biological and Environmental Sciences. Great colleagues, excellent infrastructures and startup support 🙌🏻 DL 14 September jobs.helsinki.fi/job/Helsinki...

Today @englishse.bsky.social will be at #ESEB2025 discussing the challenges and opportunities for flexible and inclusive working patterns in academia💪🏼Join in the discussion on S11 Room 122+123 @ 2.30pm! @eseb2025.bsky.social

Unfortunately I cannot be at #ESEB2025, one of my favourite conferences, but the lab is well represented with @aleksandra-marconi.bsky.social presenting her work today on S29 @3.45pm on Transposable elements and nervous and sensory system diversification in cichlid fishes. @eseb2025.bsky.social

📣 #OurLastPaper is out! This study explores the functional specialization of the symbiont-bearing organ in the rice weevil. Using microdissection coupled with dual RNA-seq, we revealed different cell types, each with distinct host-symbiont molecular dialogues. #SymbioSky doi.org/10.1186/s401...

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.

I just got the notice that all the FlyBase people at Harvard, including me, will be laid off on October 12. I'm devastated.

These databases are critical community infrastructure that need dedicated funding streams. This is an opportunity for charitable funders—Wellcome, HHMI, CZI, Gates, etc.—to make a dramatic difference in biomedical research capacity at a cost that is negligible relative to their budgets. (2/2)

Today's jobs report shows what many Americans already knew: despite record highs in the stock market, the “economy” is not working for ordinary people. Rather than accept reality & try to address it, Trump chooses to fire the bearers of bad news. This is what authoritarians do.

How Vaccines Work 🧬🧫🧪🔬💉🥽

Bon réveil 🤗 #Dupomb petitions.assemblee-nationale.fr/initiatives/...

Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...

Hanson believes the problem is not open access & APCs per se, but for-profit publishers that seek to publish as many papers as possible... the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.

Comment peut-il être possible de conduire sciemment le produit aux chiottes avec la passivité générale? On peut se foutre de la gueule des US franchement...

New preprint - varied routes to ⬆️ infection susceptibility over age - via bona fide immunosenescence, but also often via reduced tolerance 🪰🕰️🦠☠️ ⬆️ risk to die from infection predicts lifespan in males. Great group effort from the lab! www.biorxiv.org/content/10.1...

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n

I love that the title uses "delve": Delving into LLM-assisted writing in biomedical publications through excess vocabulary www.science.org/doi/10.1126/...

A new #OpenAccess study in #RESInsectConsDiv finds that the intensity and colour of #ArtificialLight at night affect insect attraction in a taxon-dependent manner doi.org/10.1111/icad.12855 #NocturnalInsects #Phototaxis @manusaunders.bsky.social @wiley.com

J'ai l’impression qu'on en parle depuis des années mais quid des actions...

🔥 Super happy with this new paper led by @sbradshaw26.bsky.social and collab with @andrewpom.bsky.social 🔥 published in Proc B today We find that meiotic drive impacts metabolic phenotypes: mito function, metabolic rate and food consumption royalsocietypublishing.org/doi/epdf/10....

CES ÉTUDIANTS JUIFS ISRAÉLIENS DÉNONCENT LE #GÉNOCIDE À #GAZA Un collectif d’étudiants, accompagnés de quelques professeurs de l’université de #TelAviv, manifestent régulièrement en soutien aux civils de Gaza. Reportage exclusif de @khadijatoufik.bsky.social. www.lemediatv.fr/emissions/20...

Super cool! (But what a word soup is “Drosophila single-cell 3D spatiotemporal multi-omics atlas “ 😅)

Mostoufi, S. L., Singh, N. D. (2024)s. Pathogen infection alters the gene expression landscape of transposable elements in #Drosophila melanogaster. G3 (Bethesda), 14(9) academic.oup.com/g3journal/ar...

New guidance published @ukrio.bsky.social to support responsible AI use in research This guidance, part of UKRIO’s priority workstream on AI and research integrity, provides a principle-based, researcher-focused resource adaptable across disciplines and technologies. ukrio.org/ukrio-resour...

Why does eating less extend lifespan? 🧬 Mutation accumulation underpins evolution of lifespan extension by dietary restriction We often think about saving energy or recycling waste - but we show how evolution acting on mutation load can generate longer life on low food 🧵 🔗 tinyurl.com/jn5ryhxv

🪰 Big news! 🪰 My first paper is officially published in The American Naturalist! We found that female Drosophila melanogaster can copy mate choices using only chemical cues - no need to witness mating, just sniff out the pheromones left behind~ doi.org/10.1086/736329 #Drosophila #BehavioralEcology

🎉Excited to share our latest paper, published in Nature Communications!🎉 "Enhancing autophagy by redox regulation extends lifespan in Drosophila" #redox #metabolism #ageing #Drosophila @natcomms.nature.com @mrc-lms.bsky.social doi.org/10.1038/s414...

Research in flies suggests #circadian systems differ in #males and #females. In PNAS Journal Club: www.pnas.org/post/journal... #CircadianRhythm #SleepWakeCycles #Drosophila #neurons

Short-term increases in rival number improves single mating productivity in male Drosophila #Competition #Insect #FruitFly #ReproductiveBehavior doi.org/10.1093/behe...

Proud of this work led by a former PhD student @aranzazuarias.bsky.social. Here, we investigated how the host controls the abundance of gut commensals and how some of them can benefit from infection. #infection #symbiosky #proudPI #immunity #AcademicSky #insect #symbiosis #Drosophila

Every disease should be considered immunological, unless proven otherwise, and Alzheimer's is looking more and more like a chronic neuroimmunological event. So we took a look at 184 patients and 105 healthy controls, via a large high-dimensional systems immunology approach. 2/8

"Quand les rédactions généralistes ont choisi, mois après mois, de ne pas parler de Gaza, de ne pas couvrir la justice internationale, de ne pas exposer les récits palestiniens, elles ont fabriqué un silence politique." www.acrimed.org/Les-medias-f...

Even worse, how three mice genotypes became what is believed to be the model of excellence?

I set up a substack. What better topic to start with than the question of whether we're overproducing PhD students. clauswilke.substack.com/p/are-we-ove...

Why did bees become haplodiploid & birds didn't? And why are stick insects perfect just the way they are? This is probably the coolest paper from @koraklein.bsky.social‬ 's PhD thesis (though there's Colias butterfly work in the pipeline which I shouldn't diss...) academic.oup.com/evolut/advan...

Democrats cannot complain about Trump’s authoritarianism while ignoring their own constitutional responsibility regarding taking the country to war. Democrats must support Sen. Kaine’s War Powers Resolution. The U.S. must not get involved in Netanyahu’s war.

Has someone found a good way of getting money out of research? Don't stop it. Copy it. APC charges cost billions. MDPI leads with over $1.7bn (est. 2015-2023). Springer-Nature ‘only’ got $1.1bn and so what do they do? They copy MDPI. the-strain-on-scientific-publishing.github.io/website/post...

Anyone in UK have a recommendation for a -20'C under bench, spark free, alarm, and digital temp display freezer? An example of one that fits the bill: www.wolflabs.co.uk/laboratory-e... Asking for a friendly lab 🙂

For the uninitiated, the band is playing "Fortunate Son" - which is a protest song against rich folk being able to dodge the draft for Vietnam. Either whoever did the set list is incompetent or it's a 14/10 troll of DJT, who got a very timely diagnosis of bone spurs in 1968 at age 22.

[ #VeilleESR #LRU ] Améliorer la performance de l’enseignement supérieur : un contrat qui reste à honorer Rapport Mme Vanina PAOLI-GAGIN pour la commission des finances @senat.fr www.senat.fr/fileadmin/cr...