Uwe Töpfer
@uwe689.bsky.social
📤 2831
📥 4800
📝 10
Postdoc Fellow
#Drosophila
#Genetics
#ExtracellularMatrix
#DevelopmentalBiology
#Morphogenesis
Drosophila SPARC Collagen IV chaperone-like activity essential for development is unique to the fat body
www.cell.com/iscience/ful...
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Drosophila SPARC Collagen IV chaperone-like activity essential for development is unique to the fat body
Drosophila fat body-derived SPARC acts as a chaperone for Collagen IV (Col(IV)), enabling their diffusion and incorporation into distal tissue basement membranes (BMs). Disruption of SPARC or Col(IV) ...
https://www.cell.com/iscience/fulltext/S2589-0042(25)00371-2
about 1 year ago
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Macrophage invasion into the Drosophila brain requires JAK/STAT-dependent MMP activation in the blood–brain barrier
journals.plos.org/Plosbiology/...
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Macrophage invasion into the Drosophila brain requires JAK/STAT-dependent MMP activation in the blood–brain barrier
The blood-brain barrier prevents immune cells and pathogens from entering the brain. This study shows that during neuroinflammation in Drosophila, immune cells can cross the blood-brain barrier by deg...
https://journals.plos.org/Plosbiology/article?id=10.1371/journal.pbio.3003035#sec014
about 1 year ago
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Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture
www.biorxiv.org/content/10.1...
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Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture
Neuronal architecture established embryonically must persist lifelong to ensure normal brain function. However, little is understood about the mechanisms behind the long-term maintenance of neuronal o...
https://www.biorxiv.org/content/10.1101/2025.02.10.637428v1
about 1 year ago
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Uwe Töpfer
Junior European Drosophila Investigators
about 1 year ago
Dear Droso peeps, we re-announce the upcoming JEDI meeting that will take place at Château du Feÿ from June 3rd to 5th in 2025. You'll find a prelim program
flies-jedi.github.io/projects/202...
We're hoping to gather about 45 of more or less young droso PI to reboot the community. -> Register Now!
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Junior European Drosophila Investigators | JEDI meeting 2025
first post COVID19 meeting
https://flies-jedi.github.io/projects/2025JEDImeeting/
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Uwe Töpfer
Marco MILAN LAB
about 1 year ago
A great initiative to spread the use of non-mammalian models in cancer research!!!!
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Beyond Mammals: Exploring Cancer Models Webinar Series (Overview) | Events Registration
Overview The Beyond Mammals: Exploring Cancer Models series will feature three webinars, each focused on one non-mammalian animal model and its applicability to cancer research. Each webinar will high...
https://events.cancer.gov/dcb/beyond-mammals
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Uwe Töpfer
about 1 year ago
We are recruiting one postdoc and one PhD student to join our lab on
#Drosophila
#innate
immunity in Lausanne (Switzerland). More info:
www.epfl.ch/labs/lemaitr...
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Open Positions
-
https://www.epfl.ch/labs/lemaitrelab/lemaitre-lab/open_positions/
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Uwe Töpfer
Rita Strack
about 1 year ago
"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here:
www.nature.com/articles/s41...
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Mechanical stresses govern myoblast fusion and myotube growth
www.biorxiv.org/content/10.1...
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Mechanical stresses govern myoblast fusion and myotube growth
Myoblast fusion into myotubes is critical for muscle formation, growth and repair. While the cellular and molecular mechanisms regulating myoblast fusion are increasingly understood, the role of biome...
https://www.biorxiv.org/content/10.1101/2024.11.22.624831v1
about 1 year ago
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On-demand delivery of fibulin-1 enables repeated basement membrane stretching
www.biorxiv.org/content/10.1...
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On-demand delivery of fibulin-1 enables repeated basement membrane stretching
Basement membrane (BM) extracellular matrices enwrap and structurally support tissues. Whether BMs are uniquely constructed to support tissues that undergo repetitive stretching and recoil events is u...
https://www.biorxiv.org/content/10.1101/2025.02.02.636120v1
about 1 year ago
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Uwe Töpfer
EMBL Events
about 1 year ago
🪰 🧬 Do you want to enhance your knowledge of Drosophila as a model organism? Then 'Drosophila genetics and genomics' might be the right course for you! Apply now and join us in Heidelberg for lectures and practical sessions delivered by renowned experts 👉
s.embl.org/drg25-01-bl
#EMBODrosophila
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Uwe Töpfer
Development
over 1 year ago
Welcome to Development's Bluesky account 🧪 Development is a leading primary research journal in developmental and stem cell biology, published by The Company of Biologists
@biologists.bsky.social
, a not-for-profit organisation, and edited by expert researchers in the
#DevBio
field.
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Development | The Company of Biologists
https://journals.biologists.com/dev
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Uwe Töpfer
Mark Peifer (He, him)
over 1 year ago
The Company of Biologists publishes multiple non-profit journals run by and for scientists across many fields, and also supports the community through meeting and travel grants and other innovations. Follow them all!
add a skeleton here at some point
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Uwe Töpfer
The Company of Biologists
over 1 year ago
ICYMI: The October FocalPlane features… webinar included talks from
@helenajambor.bsky.social
(‘How not to lie with image data’) and Kota Miura ('Reproducible bioimage analysis for ensuring
#scientificintegrity
'). Watch the recording at
bit.ly/4fyB2SU
#PublicationIntegrityWeek
#COPE
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FocalPlane features... reproducibility in imaging
YouTube video by The Company of Biologists
https://www.youtube.com/watch?v=Jt7IZzQjAFY
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Uwe Töpfer
Rodrigo Fernandez-Gonzalez
over 1 year ago
Since I have so many new friends 😄, I thought I'd advertise this. Together with
@pritiagarwal.bsky.social
and Lance Davidson, we run a Developmental Mechanics seminar series on Zoom (originally started by Ronen Zaidel-Bar). This coming Thursday, we have our last session for 2024. Join us!!
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Uwe Töpfer
Maik Bischoff
over 1 year ago
Even though there are great
#devbio
and
#biophysics
starter packs, I felt
#morphogenesis
&
#organogenesis
was missing as a subfield :D Far from complete or full. Tell me if you want to be added!
go.bsky.app/PB6s8PQ
add a skeleton here at some point
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Uwe Töpfer
Denis Wirtz
over 1 year ago
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS. For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship). Download freely here:
research.jhu.edu/rdt/funding-...
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Uwe Töpfer
Alex Eve
over 1 year ago
Developmental processes don't just occur in the embryo! Development's (
@biologists.bsky.social
) next Special Issue - Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues. Papers: 15 May 2025.
#devbio
#regeneration
#stemcells
journals.biologists.com/dev/pages/li...
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CFP | Lifelong Development | Development | The Company of Biologists
CFP | Lifelong Development | Development | The Company of Biologists Special Issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Development invites yo...
https://journals.biologists.com/dev/pages/lifelongdev
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