I’m very pleased to share our work looking at what controls condensin II cell-cycle dependant activity; a great collaboration with @eugenekimlab.bsky.social, @damlatetiker.bsky.social, Kyle Muir and Kumiko Samejima www.biorxiv.org/content/10.6...

It’s out! 🥳 Excited to share our new paper (with Kai Walstein, @andrea-musacchio.bsky.social and all others) on the role of M18BP1 in CENP-A loading! “M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans” link.springer.com/article/10.1...

Additional complementary evidence by Arianna Esposito Verza, @andrea-musacchio.bsky.social et al link.springer.com/article/10.1... and by Anais Pillan, Lionel Pintard @ccdlab.bsky.social et al link.springer.com/article/10.1... in our sister journal @embojournal.org

See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers! link.springer.com/article/10.1...

We are recruiting a Postdoc in computational biology, together with @mariasecrier.bsky.social 4yr, fully funded by @cancerresearchuk.org, ideal for Postdocs wanting to develop their independence Applications open now: www.imperial.ac.uk/jobs/search-...

Dear job rejection letters that are sent on the 22nd and 23rd of December, many thanks for making my Christmas holidays even happier.

A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration. www.nature.com/articles/s41...

Join us in Lunteren, the Netherlands on March 5 & 6, 2026 for the 32nd Dutch Cancer Biology meeting. We have two fantastic keynote speakers: @andrea-musacchio.bsky.social and @colindascheele.bsky.social and the rest of the program will be by early-career scientists. Info: www.dutchcancerbiology.nl

The Wilkinson Lab is open for science! @mskcancercenter.bsky.social 🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬 annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵 www.anthropic.com/news/claude-...

📢 New preprint: Experiment-guided AlphaFold3 resolves accurate protein ensembles. doi.org/10.1101/2025... AlphaFold3 is incredible, but has crucial limitations: it typically collapses to a single conformation, ignoring the inherent dynamics of proteins. And it can be wrong. Here's a solution. 🧵👇

New paper out now in Science! Check it out! www.science.org/doi/10.1126/...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/... Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle

As teams grow, new Ph.D. graduates are less likely to land tenure-track jobs and more likely to leave science—especially women and international researchers, according to research from last year. https://scim.ag/3JHinJs #ScienceMagArchives

They did not 😜

Why would anyone want to be a scientist? Check out our new Essay from Martin Schwartz: journals.biologists.com/jcs/article/...

The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years! Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out. link.springer.com/article/10.1...

Are you curious about what PLK1 kinase is up to these days? Have a look at our latest review on @cp-trendscellbio.bsky.social. Arianna Esposito Verza, @andrea-musacchio.bsky.social and I discuss the latest findings on a very important enzyme that is still full of surprises, 35+ years from discovery!

Happy to share our new paper out today in @cp-cellreports.bsky.social in collaboration with @tobiaswarnecke.bsky.social @akihisaosakabe.bsky.social about how evolution can do big things with small changes. www.sciencedirect.com/science/arti...

Check out our latest work on cell cycle inhibitors, which has implications for how cancer cells could become resistant to these drugs #senescence #cellcycle #cancer 🧪 www.biorxiv.org/content/10.1...

Finally out! Check out our new work on how M18BP1, known so far to be important for the epigenetic maintenance of centromeres, supports chromosome condensation when the cell enters mitosis. We also uncover a regulatory ménage á trois between condensin II, M18BP1 and MCPH1.

🚨Our latest work on selfish centromeres is published @currentbiology.bsky.social 🐭🧬We found that the spindle checkpoint contributes to non-Mendelian segregation! Huge congrats to our lab manager, Zaak Walton, who led the project🎉 Free link: authors.elsevier.com/a/1lQzN3QW8S...

Condensin II activation by M18BP1 - published by @andrea-musacchio.bsky.social Lab & @alessandrovannini.bsky.social @humantechnopole.bsky.social & Rowland Lab @nkinl.bsky.social in molecular @cellpress.bsky.social congrats to @duccioconti.bsky.social et al. www.sciencedirect.com/science/arti...

We're hiring two PhD and two postdoc positions! Interested in pollinators, soils, agroecology, pesticides? Then come and work with us and with collaborators and all over Europe! stanleyecologylab.org/vacancies #findaphd Please share!

Looking for a fully-funded D. Phil. / Ph.D. studentship in structural biology and vaccinology? Come to join our team. Fully and generously funded by a donation from the Kyner-Field family with full fees at overseas level. Join us! www.bioch.ox.ac.uk/studentships

I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social www.sciencedirect.com/science/arti... It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.

Surely you have been using AlphaFold3 for your research project? If so, have you considered #AlphaBridge to analyze the output for macromolecule complexes prediction? Web server: alpha-bridge.eu Preprint: www.biorxiv.org/content/10.1... New features coming soon!

Last week to register (March 2nd) to the next Genome Instability and Human Disease international course at @institut_curie! Gain knowledge of mechanisms ensuring genome stability, from fundamental molecular pathways up to large scale approaches.

Dishonest charts are coming from all directions, and they're only going to hit harder. Unless we push back. So, an interactive guide: Defense Against Dishonest Charts flowingdata.com/projects/dis...

Cell division aficionados: please spread out and consider registering to this conference!

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

Our spindle and kinetochore tracker paper is out! The code is available on @github.com - for those who don't like dealing with code SpinX is available via @carlzeissstiftung.bsky.social. More on expanding SpinX to multicellular environments: www.sciencedirect.com/science/arti...

Hey! Any researchers out there that are visiting Iceland this spring (Feb-Jun) and would like to present their work at our weekly seminar series at the BioMedical Center (BMC) at the University of Iceland lifvisindi.hi.is Please let me know!