Addressing complex autofluorescence signatures in solid tissue samples to enhance full spectrum flow cytometry of non-immune cells. https://www.biorxiv.org/content/10.64898/2025.12.19.695385v1

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.

🚨#JOB #alert 👉We R hiring! R U interested in #cuttingedge #AI #research that creates #Novel #immunotherapy & #clinical #impact fr #Cancer #patients via integration of #multiomics, #AI & #antibody #Engineering? 🧐Then these positions R4U! 👉Apply soon! www.kuleuven.be/personeel/jo...

NEW PREPRINT! We systematically reviewed molecular epidemiology studies looking at strain discordance in pairs of people with TB disease and history of household contact We found 30 studies from 18 countries. Excluding 4 studies at high risk of bias, we had data on 1544 household case pairs [1/n]

Rick Steves is an American treasure. Just all-around, one of the absolute best of us.

New piece from @celinegounder.com about how antivax disinformation tactics are making their way to the CDC via the McCullough foundation.

[In approx] "117 million children born during 1994–2023, routine childhood vaccinations will have prevented approximately 508 million lifetime cases of illness, 32 million hospitalizations, and 1,129,000 deaths, at a net savings of $540 billion in direct costs and $2.7 trillion in societal costs."

Is anyone here using FlowJo v11 for your #flowcytometry analysis? I'd love to hear your thoughts on this version and whether learning the new interface is worth the effort versus continuing on with v10.

Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold. Want to get a tough sample, like lung, looking like this? Read more! www.biorxiv.org/content/10.1...

Our new FlowLITE protocol for simultaneously quantifying all (human and mouse) #antibody isotypes in a single tube using #flowcytometry is out in STAR Protocols: star-protocols.cell.com/protocols/4572 Is it time to retire the ELISAs for #antibody measurements? 1/4

The CDC just announced a new study on hepatitis B vaccination on newborns in Guinea-Bissau – a move that researchers call “highly unethical” and “extremely risky”. Happy to team up with @katlay.bsky.social on this story: www.theguardian.com/society/2025...

I am delighted to introduce our new Centre of Excellence in Immune-Endothelial Interfaces (IMMENs) funded by the Research Council of Finland. www.helsinki.fi/en/researchg... I will be recruiting two postdocs early next year. One image analyst and one biologist interested in working on lymphatics!

“NIH is in crisis, grants are being terminated, labs are closing….but they found $1.6 million for an unsolicited proposal to study whether we should delay a vaccine we’ve been safely giving for 40 years, in a country where infants are at high risk of infection” www.cidrap.umn.edu/childhood-va...

We wrote two reviews on cell migration, published today in Nature Methods. They provides practical guidelines how to select a cell-migration assay and how to analyze cell-migration data Review 1: nature.com/articles/s41... Review 2: nature.com/articles/s41...

An activate-to-eliminate approach in HIV Joel N. Blankson & team report on a strategy to selectively eliminate antigen-specific HIV infected CD4+ T cells by stimulation with cognate peptides and incubation with antiproliferative drugs: doi.org/10.1172/JCI1...

THIS

Unbelievable. This would be a terrible blow to American science, writ large. It would decimate not only climate research, but also the kind of weather, wildfire, and disaster research that has underpinned half a century of progress in prediction, early warning, and increased resilience.

Dive in with MBARI for some of the most stunning deep-sea sightings we made in 2025 📽️✨️ This year, our team spotted a dazzling variety of deep-sea denizens. These fascinating finds underscore the remarkable diversity of life in the ocean. Watch here: youtu.be/_SV6sGV1Pbw?...

This is insane.

A new study says the COVID-19 vaccine protects pregnant women from getting severely ill or giving birth prematurely. www.ctvnews.ca/vancouver/ar...

✨Call open for a fully-funded PhD position✨ Looking for an enthusiastic student to join my upcoming Ambizione research group (🌱 Epigenome Diversity Lab 🌱, www.epidiversitylab.org) at ETH Zürich, starting August 2026! Apply here ↘️ jobs.ethz.ch/job/view/JOP... Application deadline: January 31st, 2026

If you’re interested in attending #TBHillDay 2026 (especially if you’re from WY, HI, AR, ID, KS, LA, ME, ND, OK, RI, or SD) you can learn more and apply here: tbfighters.org/hill-day/

🚨 PhD Position Available 🚨 I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany. www.bischofflab.com/jobs Fully funded ✅ #Cellbio #Morphogenesis #Microscopy #Drosophila #PhD (Details Below) Original Posting: stellen.uni-muenster.de/jobposting/d...

Fiddler on the roof, but with ICE agents playing the part of Cossacks. I know people think of Fiddler as a heartwarming story about a funny man doing Ya-ba-dibba-dibbas, but it's literally about pogroms like this

Something else to notice beyond Ahmed's extraordinary courage: when he approaches the shooter, another person follows him. Courage multiplies courage. If we can find it in ourselves to stand up & do what needs to be done to stop evil, others will join us. It just takes one brave individual.

Download our large database of postdoc fellowships in all fields of research. Database freely available to all; 281 fellowships. Download here: research.jhu.edu/rdt/funding-...

Nature research paper: Architecture of the neutrophil compartment go.nature.com/4oD2Nh5

What are #Neutrophils? why are there so many? how are they shaped by disease? how is it that they maintain memory despite their short lifespan? Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇 authors.elsevier.com/a/1mFj9L7PXu...

We uncover a circadian “checkpoint” in neutrophils that naturally reduces inflammation by targeting their intrinsic circadian clock! Activating CXCR4 represses circadian-related activation of neutrophils, critically reducing inflammatory injury to the infarcted heart

I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca

We need to think beyond symptom status to classify TB disease, currently we have increasing evidence that symptom reporting is unreliable to assert disease states. Very happy that i had the privilege to collaborate with this work! #TBsky #IDsky academic.oup.com/cid/article/...

Benedikt Pleyer/Nomadic Nostoc filmed these tiny ostracods collected from the beach of a Japanese island. Vargula hilgendorfii live in marine sand & emit a mix of luciferase & luciferin that lights up to deter predators. The same chemicals produce firefly glow. 海蛍: umihotaru = "Sea fireflies"

We have a PhD project as part of this scheme focused on mathematical modelling of STI transmission. Do get in touch if you are interested.

Single-cell atlas reveals alveolar macrophage-specific Oncostatin-M drives pulmonary fibrosis via fibroblast activation in PCV2d infection https://www.biorxiv.org/content/10.64898/2025.12.08.692949v1

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen rdcu.be/eT1Su

We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)! GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging. Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations. 👉 www.unige.ch/genexm/

It's happening! Canada launched two programs to recruit international researchers. Canada Impact+ Research Chairs (1 million/yr for 8 yrs +) Canada Impact+ Emerging Leaders. I will do my best to facilitate the process for those interested. Hit me up. www.canada.ca/en/impact-pl...

The traditional pipeline view of academia no longer reflects the reality of scientific #careers. In this Perspective, Alexandra A-T Weber @eawag.bsky.social reframes success as a network of paths that recognizes excellence in its many forms 🧪 #AcademicSky plos.io/4pSgzx5

Yet another study (French) shows that Pfizer/Moderna vaccines are safe and save lives. A study of 28 mil people over 4 yrs shows that 75% of vaccinated people had a lower risk of dying from severe Covid. 🧪 www.scimex.org/newsfeed/cov...

Mycobacterium tuberculosis is an outlier in many ways. One of them is keeping a high degree of functional redundancy despite its obligate pathogen lifestyle. In this review, we reflect on the biological meaning of M. tuberculosis functional redundancies. journals.plos.org/plospathogen...

This is like Mr Rogers picking up Mjolnir

A study on 1.7 million people in Hong Kong shows superior hybrid immunity to Covid in people who got vaccinated before infection vs. people who got infected first. "Our findings are a direct rebuttal to arguments for natural immunity," the authors write. doi.org/10.1016/j.va...

Biggest commitment to a 3 second joke I've ever seen

Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 MMWR A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk. www.cdc.gov/mmwr/volumes... #TxID

Please RT. Post-doc opportunity alert! 💥 closing soon 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...

This regressive move will literally kill people. It's making kids' liver cancer great again. And it's a sign of more harm to come. CDC panel recommends delaying birth dose of hepatitis B vaccine www.statnews.com/2025/12/05/c... via @statnews.com

~40% of Hepatitis B infections are caught in childhood. It is contagious enough that it can be spread just from sharing common household objects. The chance of chronic infection (ie does not clear, and is associated with high rates of liver failure and cancer) ranges from 50%-90% in this age group.

Hey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me [email protected]. Thanks!