Cortical expansion and genetic risk for PD. Led by Houman Azizi and Nooshin Abbasi. With @ptenigma.bsky.social @misicbata.bsky.social @yasharneuro.bsky.social @ndrewvo.bsky.social and many others www.medrxiv.org/content/10.6...

Need more fMRI data (beyond the amazing NSD)? Introducing MOSAIC! Incredible effort led expertly by Ben Lahner, with help from grad student Mayukh Deb. Work in collaboration with the amazing Aude Oliva! @neurosky.bsky.social. More below..

Exciting new updates to the Allen Brain Cell Atlas! 🧵👇 #neuroskyence

The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG... Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️

Aging. It happens to all of us yet we don’t fully understand how it happens. Marni and Stephen Boppart from @ahsillinois.bsky.social are developing a new microscopy platform that can illuminate the role of extracellular vesicles in cellular aging. #FrontierScience alleninstitute.org/division/fro...

We are excited to launch The Data Quartet Challenge, recognizing student contributions to projects that integrate data from at least 2 of 4 FRQ supported Quebec Alzheimer’s and Aging cohorts (PREVENT-AD, CIMA-Q, NuAge, TRIAD), with 3 prizes of 5000$ tinyurl.com/3dy899xn

Still smiling after my keynote abt Community at #useR2025 💜 Huge thanks to the organizing team for the invite, and to everyone who joined, asked questions, and shared their thoughts — you made it truly special! Slides docs.google.com/presentation... Video: www.youtube.com/live/CTTvTQ-... #rstats

Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | doi.org/10.1371/jour... How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates @plosbiology.org ⤵️

Hey #AAIC25 ! Today I'll be sharing our research on the mediating effect of WMH on spontaneous brain activity during aging! 🧠 Join me on poster 430! @ameliemetz.bsky.social @dadarmahsa.bsky.social @yasharneuro.bsky.social @roqamoqa.bsky.social

A healthy lifestyle in intervention clinical trials for weight loss, even without long term weight loss (only achieved in ~33%), led to improvement of key cardiometabolic factors academic.oup.com/eurjpc/advan...

Vascular risk factors mediate the relationship between education and white matter hyperintensities https://www.medrxiv.org/content/10.1101/2025.06.03.25328899v1

Gray matter microstructure from in-vivo diffusion MRI reflects post-mortem neuropathology severity and clinical progression of Alzheimer's disease https://www.medrxiv.org/content/10.1101/2025.05.30.25328630v1

Sex Differences in Vulnerability to Tau Pathology: Impact on Cognitive Decline https://www.medrxiv.org/content/10.1101/2025.05.25.25328324v1

Congrats to HBHL-funded researcher & 2022 HBHL New Faculty Recruit @dadarmahsa.bsky.social on being awarded the President’s Prize for Outstanding Emerging Researchers at the 2025 @mcgill.ca @healthsciences.mcgill.ca Convocation Ceremony! Well deserved. 👏 🔗 reporter.mcgill.ca/mcgills-pres...

#SpatialTranscriptomics #BatchCorrelation SpaBatch Align multi-slice sequencing-based spatial data Visium ST Stereo-seq #VariationalGraphAutoEncoder Masked data augmentation vs STG3Net STAligner SEDR DeepST SpaGIC STitch3D bioRxiv 2025 www.biorxiv.org/content/10.1...

(1/6) Thrilled to share our triple-N dataset (Non-human Primate Neural Responses to Natural Scenes)! It captures thousands of high-level visual neuron responses in macaques to natural scenes using #Neuropixels.

New paper in Imaging Neuroscience by Gustavo Chau Loo Kung, Jennifer A. McNab, et al: Non-parametric prediction of brain MRI microstructure using transfer learning doi.org/10.1162/imag...

Sneak peek from first poster session at #HBHLSymposium2025 📸 With over 100 trainees presenting their innovative research on brain health, it's a great opportunity to explore new perspectives and pioneering work from the next generation of researchers! 🖼️🎓 @healthsciences.mcgill.ca

A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images | Scientific Data www.nature.com/articles/s41...

@maximoprado.bsky.social and @mallarchak.bsky.social present their @westernubrainscan.bsky.social supported work on early biomarkers for development and monitoring of effective disease-modifying therapies at the #hbhlsymposium2025. @hbhlmcgill.bsky.social @westernu.bsky.social

Up next at #HBHLSymposium2025, @maximoprado.bsky.social & @mallarchak.bsky.social discussed their Initiative for Translational Neuroscience (ITN) collaboration & unpacked how early biomarkers help develop & monitor better treatments for neurodegenerative diseases. 🧪 @westernuresearch.bsky.social

For #TidyTuesday this week, we're looking at data on terminations of NSF grants 📊 🎨 Using colour to highlight one category 📈 Transparency to highlight the important data ✍️ Annotations instead of a legend for transparency #RStats #ggplot2 #DataViz

This Thursday I will give a talk on (causal) mediation analysis -- happy to have finally worked out what I want to tell people. And happy to pilot a new mode of slide sharing: just putting them on my website (juliarohrer.com/resources/)

You've heard of the many analysts projects, right? Scholars give the same dataset/question to a bunch of researchers & they still get different answers. Why is that? Data cleaning! This is consistent with Gelman's "garden of forking paths." Small coding decisions often drive results.

Neuroblox: A biomimetic brain modeling platform to test interventions and generate new scientific insights. www.neuroblox.org #neuroscience

Epigenetic (methylation, biological) age is associated with increased risk of dementia and brain structural changes (including atrophy). From UK Biobank's 280,000 participants, ~4,800 cases of dementia over 14-year follow-up www.neurology.org/doi/10.1212/...

Are you tired of getting signal dropout in your gradient echo EPI for spinal cord fMRI applications? Check out this new shimming study by Bréheret, D'Astous, Ma, Stockmann 🚀 👉 doi.org/10.1002/mrm....

Awesome opportunity to work on women’s brain health with an absolute star — pls repost

C-SIDE Cell type-specific inference of differential expression in #SpatialTranscriptomics 👉Work for both Sequencing- & Imaging-based ST 👉Need single-cell reference 👉Histological features as covariates 👉Pixel-based Segmentation-free DEA @naturemethods.bsky.social 2022 www.nature.com/articles/s41...

New paper in Imaging Neuroscience by Jack A. Reeves, Ferdinand Schweser, et al: IRONMAP: Iron network mapping and analysis protocol for detecting over-time brain iron abnormalities in neurological disease doi.org/10.1162/imag...

New paper in Imaging Neuroscience by Rebecca G. Clements, Molly G. Bright, et al: Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low doi.org/10.1162/imag...

@christopherjwhyte.bsky.social and I introduce a novel data-driven framework to evaluate >200 connectivity-based neural correlates of consciousness! Results are used to quantitatively compare predictions from neurodynamical models tailored to theoretic predictions. www.biorxiv.org/content/10.1...

Hey #ADPD2025 , I'm happy to present our work on characterizing brain atrophy and cerebrovascular pathology in Frontotemporal Dementia subtypes! Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02

Multi-modal Monte Carlo MRI simulator of tissue microstructure | bioRxiv www.biorxiv.org/content/10.1...

🧠📊 Just out: a deeply sample structural brain and spine dataset from the cneuromod.ca team, now published in Imaging Neuroscience! led by Mathieu Boudreau and Julien Cohen-Adad. 📰 Paper here: lnkd.in/ewXA3dED 1/🧵

That’s right, go Imaging Neuroscience! @imagingneurosci.bsky.social @anastasiayendiki.bsky.social

New @nejm.org #ACC25 The global impact of 5 cardiovascular risk factors (BP, cholesterol, obesity, diabetes, smoking) on life expectancy in men and women www.nejm.org/doi/full/10.1056/NEJMoa2415879

Finally a new textbook for theoretical neuroscience. Xiao-Jing Wang wrote a nice book with very broad coverage of the field. Highly recommend. www.amazon.com/Theoretical-...

🧠 I'm excited to share our latest publication in Nature Communications: www.nature.com/articles/s41... In this study, we explore the computational memory capacity of the brain & how it declines with aging. A big thanks to Mite Mijalkov, all other lab members for their help and amazing collaborators!

Metz et al. report that a study combining MRI brain atrophy and clinical data using machine learning achieved 89% accuracy in classifying frontotemporal dementia subtypes. Please read at:https://buff.ly/uGmX2fg @DadarMahsa @YasharZeighami @sylv_villeneuve @sducharme66

Latest work on tailoring overlapping community detection algorithms to a given network dataset, and the unique insights it can provide about human brain #complexnetwork architecture. Check the thread and preprint out below :)

Hah, the French govt, with some help from Germany, is building an open source Notion clone. Fun! github.com/suitenumeriq...

Canada joins Horizon Europe programme

🚨 New paper on ArXiv: “Uncertainty quantification and posterior sampling for network reconstruction” TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics. Short thread: 1/N

Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025... How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️

Did you know there are 400 miles of blood vessels in the human brain? Did you know there is also a complex blood–brain barrier which protects us, but also can block drug and innovative gene therapies. Rust and colleagues discuss both sides of the 'wall' that protects our brain in the journal Brain.

New paper in Imaging Neuroscience by Simen Hagen, Jacques Jonas, et al: Intracranial EEG referencing for large-scale category-selective mapping in the human ventral occipito-temporal cortex doi.org/10.1162/imag...