📅 Save the Date: Oxford 2026 Glymphatic Research Symposium! • Dates: March 30th, March 31st, April 1st 2026. • Keynote speakers: Maiken Nedergaard & Jonathan Kipnis. • Venue: Keble College, Oxford, UK. • Registration link to follow Looking forward to seeing you there! 🧠

How can one volunteer? www.montrealgazette.com/news/provinc...

Network spreading and local biological vulnerability in amyotrophic lateral sclerosis | doi.org/10.1038/s420... How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️

Huge thanks to Sanjay Kalra and the CALSNIC team, J Hansen, @vincebaz.bsky.social @goliashf.bsky.social L Collins @dadarmahsa.bsky.social @alaindagher.bsky.social !! code: github.com/netneurolab/...

The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG... Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️

New paper in Imaging Neuroscience by Malte R. Güth, Travis E. Baker, et al: Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation doi.org/10.1162/IMAG...

This important new study in Movement Disorders looked at folks w/ REM sleep behavior disorder, a common early sign of Parkinson’s. The results suggest that fMRI may reveal changes in brain networks long before symptoms of PD or dementia w/ Lewy bodies fully emerge. @parkinsondotorg.bsky.social

Companies charging and people paying up to $500,000 to select embryos with high IQ potential, even though that isn't possible. No less ethical. "Current models explain about 5% to 10% of the differences in cognitive ability between people" Front page WSJ today www.wsj.com/us-news/sili...

2. When I give seminars about this, I ask my (professional scientist) audience "How many of you believe that anthropogenic climate change is real?" Almost all hands raise. I then ask "How many of you have read the IPCC report or equivalent" Fewer than 25% of hands raise.

Yesterday I decided to become a Samsung phone user. Today I am a separatist. Never say never! 😀 globalnews.ca/news/1132233...

How does cerebral #BloodPerfusion map onto micro-, meso- & macro-scale brain structure? @asafarahani.bsky.social @misicbata.bsky.social &co characterize blood perfusion in the #HumanBrain, revealing how it changes with age & in #NeurodegenerativeDisease @plosbiology.org 🧪 plos.io/46AEURS

Integrating and interpreting brain maps | doi.org/10.1016/j.ti... Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

"The Quebec government has served the school with fines totalling almost $30 million for violating the province’s language law by admitting too many students to its English-taught continuing-education programs over the last two years." Read more at: www.montrealgazette.com/news/article...

In collab with @alaindagher.bsky.social @misicbata.bsky.social and Shady Rahayel, we used the SIR model to computationally model neurodegenration as a function of the structural connectome and gene expression. SIR cpatures the dynamics better than axonal connectivity (very bad!) and gene expression!

On the root cause of global obesity www.pnas.org/doi/suppl/10... www.science.org/content/arti... www.washingtonpost.com/wellness/202...

Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social‬! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...

Hi everyone! Blue Sky seems alright! Check out our massive new review on Coenzyme Q that earned the cover 😉.

ENIGMA is a tremendous achievement ! Congratulations @ptenigma.bsky.social

New paper in Imaging Neuroscience by Stephen M. Smith, Karla L. Miller, and Thomas E. Nichols: Characterising ongoing brain aging and baseline effects from cross-sectional data doi.org/10.1162/IMAG...

Does the carbon footprint calculation include travel to hackathons?

🧵 Beautiful new preprint by @marishishi.bsky.social on the genetic architecture of impulsivity. With the UCSD team of Sandra Sanchez-Roige, Abe Palmer et al. and Lang Liu, Ziv Gan-Or @ukuvainik.bsky.social @filipkmorys.bsky.social @misicbata.bsky.social and others www.biorxiv.org/content/10.1...

"The extraordinary thing is just how tiny [the fishing] industry is, yet it seems to hold the world’s governments to ransom" www.theguardian.com/commentisfre...

🔥 Just out! Our new massive global ENIGMA-CNV study led by Ana Silva + David Linden (+90 authors!) reveals how rare copy number variants (CNVs) in the human genome disrupt brain structure. Landmark in human genetics 🧨 Basically

New preprint. @ndrewvo.bsky.social‬ and @enigmabrains.bsky.social‬ analyzed MRI of > 3,000 people with Parkinson’s disease. W-score method to compare PD to matched controls confirmed extensive loss of cortical thickness, surface area and subcortical volumes in PD, even in early stages

The best thing about this is the chess clock on the desk - JP thought this was going to be like those chess grandmaster versus 20 kids exhibitions - except the kids trounced him.

Front page, NYT today Nothing has been proven to reverse Alzheimer’s disease, including this false claim gift link www.nytimes.com/2025/05/21/w...

Just stealing the Quebec govt's ideas. www.bbc.com/news/article...

Contrary to Clear, Verifiable Facts, Secretary Kennedy Continues to Repeat Harmful Myths About Alzheimer’s and Dementia Research www.alz.org/news/2025/ke...

Inspiring celebration of David Attenborough from Kate Winslet and many others - and a much-needed reminder to stand with science www.theguardian.com/tv-and-radio...

New paper in Imaging Neuroscience by Kirsten M. Lynch, Jeiran Choupan, et al: Perivascular and parenchymal fluid characteristics are related to age and cognitive performance across the lifespan doi.org/10.1162/imag...

🧠New preprint! What drives tau, the pathological protein in AD, to spread? We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out:
www.biorxiv.org/content/10.1...
 #MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology

Beautiful update by Michael Frank on models of dopamine signaling in the basal ganglia www.annualreviews.org/content/jour...

Blog post: Matthew Yglesias on group differences: It isn't about manners. ericturkheimer.substack.com/p/matthew-yg...

Will UofT also consider Canadian researchers from a province whose govt relentlessly attacks (some of) its universities and (all of) its minorities? www.cbc.ca/news/canada/...

If Canada did join the US, Alberta and Quebec would be "red states". www.montrealgazette.com/news/provinc...

🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia" medrxiv.org/content/10.1... We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇

Can't get enough romantic piano concertos but you've listened to all the famous ones? This is very nice. music.apple.com/ca/album/rub...

New: Energy use shapes brain organization and development. We use gene expression maps from the @alleninstitute.bsky.social Human Brain Atlas to map the main energy metabolism pathways in the brain. Led by @moohebatpe.bsky.social @misicbata.bsky.social @goliashf.bsky.social and Justine Hansen 🧵

Exciting news—our recent study, a collaboration between the Rouleau and Dagher labs, linking Essential Tremor genetic risk to MRI outcomes in unaffected individuals has been published in Movement Disorders! doi.org/10.1002/mds.... @mcgill.ca @theneuro.bsky.social @alaindagher.bsky.social

Alpha-synuclein co-pathology promotes tau accumulation in Alzheimer’s disease - findings by ISD investigators published in Molecular Neurodegeneration 👏 rdcu.be/ed0Su @nfranzme.bsky.social @springernature.com

Understanding #Parkinsons subtypes is key to more targeted RCTs & better therapeutics! 🧠 Our new study finds that LRRK2 PD patients show milder cortical atrophy, with preserved temporal & occipital regions compared to sporadic PD. #LRRK2 #dataviz www.medrxiv.org/content/10.1...

They might have a point ... :-) www.lapresse.ca/internationa...

We should also split up the National Hockey League into two separate entities: (1) Canadian and European Teams (mostly Scandinavian) call it the I-NHL and its champion is awarded the Stanley Cup each year and (2) a USA-Russia league (throw in N Korea) and it gets to keep Gary Bettman.

Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025... How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️

A very old paper worth reading for Parkinson's disease history aficionados. You will learn in it that the initial attemps to use L-DOPA to treat Parkinson's were carried out in 1961 in Montreal and in Vienna. pmc.ncbi.nlm.nih.gov/articles/PMC...

Questioning the dogma that high glycemic foods leads to hunger and increased intake. A randomized trial of different glycemic index consumption www.cell.com/cell-metabol...

For the past 30 years medical students from all over the world have come to our hospital for electives. Now, sadly, McGill has been forced to suspend all international electives. I'm embarrassed. Legault = Trump-lite.

I am really enjoying this Naxos series of Russian Piano Trios - I only know some of this music - but it's all good. Highly recommend. music.apple.com/ca/album/his...

Hi @hbhlmcgill.bsky.social it's a bit annoying to see you "celebrate" my grant since your recent decisions almost forced me to shut down my lab - and indeed- without this operating grant from CIHR that seemed likely...

2024 was the first full calendar year for Imaging Neuroscience @mitpress - 350 papers published. We're proud of how the brain imaging community enthusiastically embraced open access non-profit publishing. Our aim is to be *your* journal. Full size PDF: drive.google.com/file/d/1M170...