Implementation of the genome-informed risk assessment (GIRA) may lead to large disruptions to the health system https://www.medrxiv.org/content/10.64898/2026.02.25.26347123v1

Evidence for sexual antagonism and antagonistic pleiotropy in the maintenance of late onset Alzheimer's disease alleles https://www.medrxiv.org/content/10.64898/2026.02.26.26347171v1

Real-world utilization and initial experience with aflibercept-ayyh (PAVBLU(R)) for retinal disorders in United States retina practices: A descriptive retrospective analysis https://www.medrxiv.org/content/10.64898/2026.02.25.26345681v1

Automated Segmentation of Post-Surgical Resection Cavities on MRI in Focal Epilepsy: a MELD Study https://www.medrxiv.org/content/10.64898/2026.02.26.26347093v1

Finding the groove in neural space https://www.medrxiv.org/content/10.64898/2026.02.26.26347169v1

Clinical Evaluation of a Digital Biomarker for Joint Swelling in Inflammatory Arthritis based on Automated Quantification of Dorsal Finger Fold Patterns https://www.medrxiv.org/content/10.64898/2026.02.26.26347165v1

Temporary Shock or Lasting Scar? Life Expectancy Trajectories Since COVID-19 https://www.medrxiv.org/content/10.64898/2026.02.25.26347112v1

Characterising associations between mental distress, mobility, and COVID-19 restrictions: a U.S. study https://www.medrxiv.org/content/10.64898/2026.02.26.26347164v1

Apathy in Mild Behavioural Impairment: Associations with Cortical Thickness and Grey Matter Volume https://www.medrxiv.org/content/10.64898/2026.02.25.26347107v1

Constructing and analyzing a synthetic life course cohort based on pooling two data sources: A case study of early adulthood depression symptomatology and late-life cognition https://www.medrxiv.org/content/10.64898/2026.02.25.26347113v1

Work-related stress and consumption of psychoactive substances and medications among early childhood professionals in Orleans Metropole, CCTVL, and Fleury-les-Aubrais (TraPsyCOL): Study protocol for a cross-sectional study https://www.medrxiv.org/content/10.64898/2026.02.25.26347115v1

Spatial Clustering of School Susceptibles Drives Divergent US Measles Outbreaks https://www.medrxiv.org/content/10.64898/2026.02.25.26347103v1

Continuous glucose monitor-derived glucotypes and cardiovascular risk scores in individuals without diabetes https://www.medrxiv.org/content/10.64898/2026.02.25.26347035v1

International healthcare experts' consensus on the key requirements of a potential international patient safety learning system: a modified online Delphi study https://www.medrxiv.org/content/10.64898/2026.02.25.26347126v1

Misclassification of heritable mortality undermines estimates of intrinsic life span heritability https://www.medrxiv.org/content/10.64898/2026.02.26.26347172v1

Effect of an integrated housing intervention for people involved in the criminal-legal system who have housing instability https://www.medrxiv.org/content/10.64898/2026.02.25.26347012v1

Leveraging pediatric emergency visits as early signal for respiratory hospitalization forecasting https://www.medrxiv.org/content/10.64898/2026.02.25.26347074v1

Differential Metabolic Signatures of Cushing's Disease Patients Dependent on their Obesity Status https://www.medrxiv.org/content/10.64898/2026.02.25.26346994v1

Remote Patient Monitoring in Heart Failure: Firm Evidence for Mortality Reduction and a Critical Geographic Evidence Gap - Systematic Review, Meta-Analysis, and Trial Sequential Analysis https://www.medrxiv.org/content/10.64898/2026.02.25.26347143v1

Estimating malaria attributable fraction using quantitative PCR in a longitudinal cohort in Eastern Uganda https://www.medrxiv.org/content/10.64898/2026.02.24.26347052v1

Evaluating Mid-Upper Arm Circumference Cut-Offs as a Screening Tool for Undernutrition in Pregnant Women: An Alternative to Body Mass Index https://www.medrxiv.org/content/10.64898/2026.02.25.26347073v1

Epidemiological characteristics and vaccination impact scenario modelling of concurrent Clade I mpox outbreaks in the Democratic Republic of the Congo and Burundi https://www.medrxiv.org/content/10.64898/2026.02.24.26346883v1

Long-term morphometric similarity gradients relate to cortical hierarchy and psychiatric symptoms in schizophrenia https://www.medrxiv.org/content/10.64898/2026.02.25.26347075v1

Mild Behavioural Impairment-Apathy and Alzheimer's Disease Plasma Phosphorylated Tau Biomarker Levels https://www.medrxiv.org/content/10.64898/2026.02.25.26347102v1

Time, talk, and teamwork: Perceptions of personalised dementia care planning conversations in primary care https://www.medrxiv.org/content/10.64898/2026.02.20.26345977v1

Analytical Validation of an ELISA assay for Maternal Autoantibody Related Autism https://www.medrxiv.org/content/10.64898/2026.02.25.26347095v1

Novel adenoma-immune phenotypes are associated with risk of metachronous polyps and colorectal cancer in a bowel screening cohort https://www.medrxiv.org/content/10.64898/2026.02.25.26346992v1

Genetic susceptibility versus fibrosis progression in North Indian MASLD: distinct roles of APOC3 and PNPLA3 in a candidate gene study https://www.medrxiv.org/content/10.64898/2026.02.25.26347059v1

Efficacy of Vitamin C in Acute Musculoskeletal Pain Management: A Double-Blind Randomized Controlled Pilot Study https://www.medrxiv.org/content/10.64898/2026.02.25.26347033v1

Behavioral and Healthcare Determinants of Self-Reported Scabies in Chiwanda Ward, Nyasa District, Tanzania https://www.medrxiv.org/content/10.64898/2026.02.25.26347071v1

Impact of violence on HIV outcomes among female sex workers: A global systematic review and meta-analysis https://www.medrxiv.org/content/10.64898/2026.02.27.26346881v1

Psychometric evaluation of The Index of Myalgic Encephalomyelitis Symptoms (TIMES). Part II: Criterion-related and discriminant validity, test-retest reliability and minimal detectable difference. https://www.medrxiv.org/content/10.64898/2026.02.25.26347081v1

Development of a Multi-Trait Polygenic Score for Intrinsic Capacity https://www.medrxiv.org/content/10.64898/2026.02.25.26347054v1

Genetic Evidence for Opposing Associations of Psoriasis and Type 2 Diabetes with Inflammatory Bowel Disease: A Mendelian Randomization Study https://www.medrxiv.org/content/10.64898/2026.02.25.26346967v1

Interpretable machine-learning model for cataract associated factors identifying in patients with high myopia https://www.medrxiv.org/content/10.64898/2026.02.25.26347145v1

Cognitive and Behavioral Functioning in Female Former Soccer Players: Results from the Head Impact and Trauma Surveillance Study (HITSS) https://www.medrxiv.org/content/10.64898/2026.02.25.26347083v1

Parkinson's Disease motor and non-motor progression models emerge from pathway-level transcriptomics https://www.medrxiv.org/content/10.64898/2026.02.25.26346261v1

Segmentation of metabolically relevant adipose tissue compartments and ectopic fat deposits https://www.medrxiv.org/content/10.64898/2026.02.25.26347069v1

Heterogeneity, Longitudinal Decline, and Metabolic Risk in MRI-Based Quantification of 20 Individual Hip and Thigh Muscles https://www.medrxiv.org/content/10.64898/2026.02.25.26347009v1

Accuracy and efficiency of using artificial intelligence for data extraction in systematic reviews. A noninferiority study within reviews https://www.medrxiv.org/content/10.64898/2026.02.25.26347053v1

A norm-anchored framework for characterizing cognitive heterogeneity in schizophrenia https://www.medrxiv.org/content/10.64898/2026.02.25.26347062v1

Multimodal EHR-Based Prediction of Pediatric Asthma Exacerbations https://www.medrxiv.org/content/10.64898/2026.02.25.26347091v1

Eosinophil and eosinophil-derived novel leukocyte ratios are strong predictors of the severity of acute coronary syndrome patients https://www.medrxiv.org/content/10.64898/2026.02.20.26346670v1

Multicentre validation and update of a Legionella prediction score to guide testing and treatment in community-acquired pneumonia https://www.medrxiv.org/content/10.64898/2026.02.25.26347092v1

Growth, infection, and humoral immunity in children who are HIV exposed and uninfected https://www.medrxiv.org/content/10.64898/2026.02.25.26347096v1

Projected impact of a national Tobacco 21 policy in the Kingdom of Saudi Arabia https://www.medrxiv.org/content/10.64898/2026.02.25.26347109v1

Does the type of publisher response to integrity concerns influence subsequent citations? A cohort study. https://www.medrxiv.org/content/10.64898/2026.02.25.26346683v1

Familial medullary thyroid carcinoma secondary to an SLC30A9 intragenic deletion and translation reinitiation https://www.medrxiv.org/content/10.64898/2026.02.26.26346165v1

Statistical uncertainty explains the poor agreement in polygenic scoring for type 2 diabetes https://www.medrxiv.org/content/10.64898/2026.02.25.26347015v1

RARE CODING VARIANT ASSOCIATIONS WITH PRIMARY OPEN-ANGLE GLAUCOMA IN AFRICAN ANCESTRY:A MULTI-COHORT EXOME-WIDE META ANALYSIS https://www.medrxiv.org/content/10.64898/2026.02.25.26347141v1