Cilia alert! Stoked to have the new paper from Juyeon Hong about a new domain at the extreme distal tip of motile cilia! (The EDT, y'all!) It's out now @natcomms.nature.com. Check it out! #cilia www.nature.com/articles/s41...

Compound heterozygous DAW1 variants reveal tissue-specific roles in left-right patterning and congenital heart disease without primary ciliary dyskinesia https://www.medrxiv.org/content/10.64898/2026.01.27.26344789v1

The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1–4 September 2026 will highlight the advances in the field of centrosome #research. Register now! Deadline: 1 June https://meetings.embo.org/event/26-centrosomes#Centrosomes#Lausanne#research#EMBOCentrosomes #EMBOevents #conference 🧪

Come and work with us! We're looking for a talented postdoc with interests in developmental biology, cancer and the primary cilia to join us @mortlab.bsky.social. An exciting MRC funded collaboration with Pleasantine Mill - @cilialab.bsky.social. Further details: www.jobs.ac.uk/job/DPR804/s...

Excited to be sharing our work on Togaram1 mouse knockout and brain development in this e-Symposium Tuesday, January 13, 2026! 10:00 AM EST in the US = 15:00 GMT #cilia #centrosomes #devbio 🐭🧠🧪

25 years of Xenbase. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Good start for 2026: Our work on mucociliary progenitors and how FOXI1 regulates them as well as ionocyte specification is now out and open access. tinyurl.com/Bowden-Engel... Congrats to all authors and thanks to @dfg.de @cibss.bsky.social @sfb1453.bsky.social @for5547.bsky.social for support!

Modern Xenopus research uses this system to study #devbio, genetic diseases, biomechanics, and cell biology. If you want hands-on experience, register now to the CSHL Cell & Developmental Biology of Xenopus: Gene Discovery & Disease meetings.cshl.edu/courses.aspx... Deadline: January 16, 2026

We must have been #ExtraNice this year- our #cilia & #centrosome 🧪 community- 🎅 Santa just dropped the 1st session of 2026 line-up @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposia- www.eventbrite.co.uk/e/bscb-genso... See you on the other side! Happy Holidays!

Robust ciliary flows protect early Xenopus embryos from pathogens independent of multiciliated cell patterning https://www.biorxiv.org/content/10.64898/2025.12.19.694354v1

🌍 Cilia2027 | Mar 8–12, 2027 | 📍 Stresa, Lake Maggiore, Italy Join the global cilia community for science, collaboration & discovery (+ fun!!). #Cilia2027 #CiliaBiology

CDKL5 Deficiency Disorder (CDD) leads to seizures & intellectual disability. This study shows that #Chlamydomonas CDKL5 kinase is activated by the LF2/CDK20 kinase; CDKL5 in turn regulates #intraflagellar transport via protein abundance & phosphorylation #cilia @plosbiology.org 🧪 plos.io/45490eP

We are also featuring developmental biologist K. Vijayraghavan, a @dev-journal.bsky.social Advisory Board member and a Development and @biologyopen.bsky.social author, as an extraordinary biologist this week. #100biologists @kvijayraghavan.bsky.social

How does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH

Starting in a few mins.!! #Cellbio2025

Curious about what’s new in cilia/ciliated cells? Come find out at mini-symposium: Cilia Biogenesis, Structure & Function at #CellBio2025 @ASCBiology! Organised by Karl Lechtrek, Caroline Ott, Martin Engelke & @caylajewett.bsky.social — marking 25 years of cilia-in-disease discovery.

Attending #Cellbio2025? I am presenting two posters, stop by if you are interested in epithelial dynamics. Looking forward to all the amazing conversations and feedback!!

SPEF1 mediates assembly of the central pair microtubule complexes in cilia of Tetrahymena. https://www.biorxiv.org/content/10.64898/2025.12.03.689828v1

Now out from our lab in @currentbiology.bsky.social! An mTOR-Stat3-Stathmin pathway controls #centrosome and #microtubule dynamics for #oocyte polarization www.cell.com/current-biol...

Very excited to share the latest work from our lab in @insight.jci.org, highlighting a role for the #septin #cytoskeleton in protecting against "leaky gut", by recruiting non-muscle myosin II and stabilizing the tight junction. Credit to @dominikrobak.bsky.social for the stunning cover image!

Last call! Applications for the @crg.eu International PhD Programme 2025 in beautiful Barcelona close next week! Join us and our inspiring colleagues at the CRG - an exceptional environment for discovery, creativity, and scientific growth. Apply here: www.crg.eu/en/content/t...

Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526

Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...

The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease. If you or someone you know might be interested, please share or reach out! 🧠✨ #Neuroscience #Cilia #Postdoc #neuro #SFN neurojobs.sfn.org/job/39311/po...

Amanda Smith, Lawrence Ostrowski and colleagues find that lipid nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models. #JCSciliaSI journals.biologists.com/jcs/article/...

I am excited to share our preprint on the use of machine learning to identify abnormal cilia function. I am proud of Nicholas Hadas, a talented PhD candidate, for his hard work in compiling the code and preparing this manuscript. www.biorxiv.org/content/10.1...

🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio

Yongli Zhang, Xuecheng Li, Zhengmao Wang and Junmin Pan find that SAXO proteins stabilise axonemal microtubules by reducing tubulin turnover to regulate ciliary length and assembly, without affecting ciliary motility. #JCSciliaSI journals.biologists.com/jcs/article/...

Taiju Fujii, Norihito Murai, Kazuhisa Nakayama and colleagues find that β-arrestin connects the BBSome and GPR161, mediating the export of GPR161 from cilia upon Hedgehog signalling activation. #JCSciliaSI journals.biologists.com/jcs/article/...

We have PhD and Postdoc positions open in our group. Join us in Lausanne to explore how cells pull off extreme shape changes and how cilia drive biological flows. You can find more details on the projects available and how to apply in our website: www.epfl.ch/labs/lpl/joi...

Cold Spring Harbor Laboratory Course - Cell & Developmental Biology of Xenopus: Gene Discovery & Disease, April 7 - 21, 2026. Application Deadline: January 16, 2026 xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Singh, A., Thale, S., Leibner, T., Lamparter, L., Ricker, A., Nüsse, H., Klingauf, J., Galic, M., Ohlberger, M., & Matis, M. (2024). Dynamic interplay of microtubule and actomyosin forces drive tissue extension. Nature communications, 15(1), 3198. #EpithelialMechanics buff.ly/Nwi5TVv

PAK4 dynamics at actively remodeling vertices 🌟 ⚡👀 Check out our recent preprint www.biorxiv.org/content/10.1...

Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells

A new platform enables the creation of customizable, cilia-powered biobots from human lung cells, offering potential for precise therapeutic delivery and disease modeling in complex biological environments. doi.org/g9462c

Beautiful drawing of ciliogenesis in airway cells from Sorokin, 1968: journals.biologists.com/jcs/article/.... Just shown on stage by @mahjoublab.bsky.social at #GEF25

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary

Cilia and aECM, what more could you want? www.biorxiv.org/content/10.1...

Our new preprint 😅 ! We show cytokinetic abscission completion is important to maintain polarized epithelial structure, and p53-mediated apoptosis guards the structure when there are failures of abscission. In vivo in brain. #cellbio #abscission #devbio #cilia www.biorxiv.org/content/10.1...

I am delighted to see this amazing collaborative paper out in press. Using gene edited human ES cells differentiated into airway epithelium to uncover a novel role for MCIDAS in multiciliogenesis. www.cell.com/cell-reports...

Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation. https://www.biorxiv.org/content/10.1101/2025.09.17.676780v1

Functionally Essential and Structurally Diverse: Insights into the zebrafish Left-Right Organizers Cilia via Optogenetic IFT88 Perturbation and Volume Electron Microscopy https://www.biorxiv.org/content/10.1101/2025.09.08.674930v1

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

Now that the 20th International Xenopus conference is over it is time to rest my geeky earrings. I had a great time catching up with people and discussing welfare research priorities. Interested in the amphibian welfare webinars I mentioned? Here’s the link: nc3rs.org.uk/3rs-resource... #IXC25

🚨 New in The EMBO Journal! Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins. 🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social 📄 www.embopress.org/doi/full/10....

Super excited to share my PhD work! How do different subunits of the Outer Dynein Arm (ODA) complex navigate the crowded cytosol and find each other to assemble into functional motors that power motile cilia? Check out this preprint- #cilia#axonemaldyneins#proteincomplexassembly#trypanosomes

New from Verhey lab @kjverhey1.bsky.social: "a renewable source of antibodies with high specificity and affinity towards tubulin glutamylation and acetylation" recombinant rMAb-GT335 and rMAb-611B1 #microtubule #cilia #tubulin onlinelibrary.wiley.com/doi/10.1002/...

Save the date! March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳 Stay tuned for more info!

ICYMI: Air pollution PM2.5 harms airways and lungs, largely by impairing mucociliary clearance. Yasutaka Okabe & team now link aldehyde metabolism with cilia regeneration—and mitigate pollution effects in mice using the small compound Alda-1: buff.ly/BtE3Pyd