Revealing lysine-specific histone demethylase 1a as a new target for kidney diseases Tobias B. Huber & team show LSD1 regulates kidney development, and its dysfunction disrupts key kidney cells, leading to cyst formation in mouse and organoid models: doi.org/10.1172/jci....

Today we are celebrating #WorldKidneyDay20Years 🎉 #WorldKidneyDay

Together with four other Freiburg CRCs, @sfb1453.bsky.social joined the @friasunifreiburg.bsky.social workshop to discuss "What it takes to build and lead successful interdisciplinary research initiatives" If you want to know more check out the great summary by our CRC 1597 colleagues t1p.de/wlkqd

Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1. ⬇️ www.sciencedirect.com/science/arti...

Good start for 2026: Our work on mucociliary progenitors and how FOXI1 regulates them as well as ionocyte specification is now out and open access. tinyurl.com/Bowden-Engel... Congrats to all authors and thanks to @dfg.de @cibss.bsky.social @sfb1453.bsky.social @for5547.bsky.social for support!

Congratulations to NephGen PIs Melanie Börries and Sven Diederichs and their groups on their practise changing publication in @natgenet.nature.com 👏👏 #MedSky #OncoSky rdcu.be/eUbf3

NephGen speaker Anna Köttgen attendend the first ERA Science Meeting in November to further improve precision medicine in genetic kidney diseases #NephSky #MedSky See link for more details 👇 www.linkedin.com/posts/europe...

A new exciting and highly collaborative @sfb1453.bsky.social paper by NephGen groups Börries, Schell, and Kühn in @pnas.org Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease | PNAS www.pnas.org/doi/10.1073/...

Pascal Schlosser and Matthias Wuttke, our @sfb1453.bsky.social representation and speakers at this year's #kidneywk

Congratulations to @sfb1453.bsky.social PI Tobias Hermle and his team for their groundbreaking work on slit diaphragm architecture. Go check it out 👇 rdcu.be/eOzXF

Our study on the genetic determinants of kidney structure is available online in Kidney International as a pre-proof! We used a CNN to derive kidney sub-volumes from MRIs and performed a GWAS to uncover their genetic determinants. Thanks to all involved! #CKD #Imaging #DeepLearning #GWAS

A massive shoutout to our @sfb1453.bsky.social colleague Nora Scherer from Anna Köttgen's group for receiving the @dgfn.bsky.social Rainer-Greger-Award for her outstanding dissertation! Congratulations and so well deserved!!! 🎉👏

We are delighted that our external advisory board member @ksusztak.bsky.social will be receiving this year’s Homer Smith Award at Kidney Week 2025. www.kidneynews.org/view/journal... Congratulations Katalin, so well deserved! 👏👏💐

Brilliant presentations by our NephGen PIs Anna Köttgen, Ulla Schultheiss, Michael Köttgen and Sven Diederichs in the @sfb1453.bsky.social session at this year's Annual Meeting of the @dgfn.bsky.social #Nephrologie #dgfn

Association of Serum Afamin Concentrations With Kidney Failure in Patients With CKD: Findings From the German CKD Cohort Study bit.ly/4fWGYES #OpenAccess #VisualAbstract

Super cool project! Maybe it's time for a NephGen comic? 🤔

Thank you to everyone who joined this years' EUKISS Summer School!!! 🎉🙏 It was an amazing meeting with lovely people, impressive science and hopefully many future collaborations and projects. 😍 See you next year in Aachen! #EUKISS25 #EUKISS

Huge congratulations to Dr. Magdalena Brislinger-Engelhardt for defending her PhD thesis today 👏👏👏🥳🥳🥳

Registration for this year’s EUKISS summer school in Freiburg, Germany, is now open! Join us in July for two days of discussions around the basis of kidney functions and their relevance for kidney disease! Registration & program ➡️ www.eukiss.org

🧬 Looking forward to presenting at the #ESHG2025! Our GWAS & EWAS studies of 10,000+ individuals reveal how genetics & epigenetics regulate trace element metabolism. Visit our poster P18.057.D today at 4pm! Huge thanks to @sfb1453.bsky.social, @zkutalik.bsky.social, and all collaborators involved!

Congratulations to the CIBSS team for this outstanding achievement! So well deserved!!! 🎉👏👏

Wondering whether you should read the great kidney disease genetic scorecard paper by @hongbo919.bsky.social @ksusztak.bsky.social on 2.2Mio people? Here 👇 rdcu.be/eejuB Matthias Wuttke at @sfb1453.bsky.social and I report some highlights for you (and recommend reading the original work) #nephgen

please re-post! we are looking for a PhD candidate: www.uniklinik-freiburg.de/en/career/jo...

Today is #WorldKidneyDay! #MedSky #NephSky #StandUpforScience

#RareDiseaseDay #NephSky #MedSky

🚨2 fully funded postdoc positions for 6 years 🚨 Are you interested in gene regulation, cardiovascular diseases or aging? Join our team in beautiful Graz, Austria! Postdoc in Bioinformatics 🖥️ tinyurl.com/3ufv767b Postdoc in functional genomics and models (e.g. organoids) 🧪 tinyurl.com/4ucahvzn

Freiburger Forschende zeigen, wie seltene „Nonstop-Mutationen“ die Proteinbildung stören und die Entstehung von #Nierenkrebs fördern können. Erkenntnisse bieten Potenzial für bessere Diagnosen und Therapien. Link zur Studie: t1p.de/ytfs3 #Medizin #Forschung

This study challenges the idea that KDM5D in male cells functions equivalently to the second KDM5C allele in female cells, implicating an interplay between KDM5C mutation and Y chromosome loss in ccRCC development in men. @sfb1453.bsky.social www.nature.com/articles/s42...

Congratulations to @sfb1453.bsky.social PIs Athina Ganner, Elke Neumann-Haefelin, Ian Frew, and Sven Diedierichs and their teams! 👏👏👏 Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation www.science.org/doi/10.1126/...

For NephGen every day is International #WomenInScienceDay 🔬👩‍🔬🎉 #WomenInScience #WomenInSTEM #February11

Join us for the fantastic annual @cshlnews.bsky.social #Xenopus cell & developmental Biology course. Deadline for application is Jan 31st. meetings.cshl.edu/courses.aspx...

And another brand new publication for @sfb1453.bsky.social: Published by Ian Frew and his group in collaboration with Anna Köttgen, Melanie Börries and Natalie Köhler in @kidneyint.bsky.social 🎉🎉🎉 #NephSky www.kidney-international.org/article/S008...

What a nice way to start the new year! Check out our article on the influence of rare #genetic variants on human #metabolism in the current issue of Nature Genetics rdcu.be/d5ov1 Thanks to all collaborators and funders, @dfgpublic.bsky.social

Our amazing @sfb1453.bsky.social speaker and leading PI of #nakogesundheitsstudie Freiburg Anna Köttgen gave an interview to the #BadischeZeitung 👏 👏 www.badische-zeitung.de/diese-frau-l...

While we're at it: We are looking for 2 postdocs. One with experience in dev. Biol (pref. With mouse experience) and one with bioinformatics / modeling / multi-omics experience. Exceptional PhD candidates will be also considered for the project via IMPRS @mpi-ie.bsky.social recruitment.

Check out our newest joint publication by @sfb1453.bsky.social PIs Anke Schumann, Christoph Schell @nephpath.bsky.social, Oliver Schilling and Michael Köttgen in #ScientificReports‍ 👩‍🔬👨‍🔬🔬🎉. #NephSky @uniklinik-fr.bsky.social @uni-freiburg.de rdcu.be/d3UXF

NephGen follows the blue butterfly now! Looking forward to sharing and discussing all the latest news about nephrology, kidney physiology and pathology, cilia, epidemiology and much more 🥳🧐