Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines. www.biorxiv.org/content/10.6...

🚨 3 weeks to go! 🚨 Join us for the 2nd LA Mass Spec Day 🧪✨ 📅 Oct 17, 10am–5pm 📍 UCLA South Bay Campus Plenary talks • Contributed talks • Posters • Networking 👉 Register: lnkd.in/gFdW9rfG 👉 Abstracts: lnkd.in/gb-Qq7d5

Congrats to Benjamin Cravatt on receiving the 2025 Tetrahedron Prize for Creativity in Bioorganic & Medicinal Chemistry from @elsevierconnect.bsky.social, honoring his pioneering activity-based protein profiling (ABPP) to study and target disease-relevant proteins.

Excited to share our latest work developing molecular glue degraders of ZBTB11, now out in @natchembio.nature.com www.nature.com/articles/s41...

“This Executive Order is nothing short of obscene," said Ranking Member Zoe Lofgren (D-CA). "In what world does Donald Trump think that Americans want political appointees – who, need I remind the President, are unelected bureaucrats – making decisions on what science gets funded?”

The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.

35 non airport-only visits

A major NIH grant to study ways to restore hearing was terminated by the Trump administration bc it was awarded through a DEI initiative—to a researcher who qualified bc of his own hearing loss www.cnn.com/2025/07/29/h... @manorlaboratory.bsky.social

This piece in Science: *confirms that the push for multi-year funding is coming from White House, against NIH wishes *White House is deliberately slowing spending already appropriated to then cut it via rescission www.science.org/content/arti...

🧬Power your research with GlycoNet Integrated Services’ Molecular Glycobiology node at the ‪@ualberta.bsky.social‬ Offering: Custom cell & mouse models (CRISPR, transgenics) Siglec-Fc protein production Cell engineering & expert support Explore more services: canadianglycomics.ca/services/

🔥 Job alert! We are looking for an enthusiastic PhD candidate in the new Chemical Glycobiology Lab at @tudresden.bsky.social! Master in Chem or similar, experience in organic chem including chemoenzymatic, and most importantly: enthusiasm! Deadline 8th July: www.verw.tu-dresden.de/StellAus/ste...

Humans don't reproduce long enough to put evolutionary pressure against amyloids. Other animals? We find older-living animals (whales, crocs, etc.) have synuclein that is less prone to aggregation (in vitro) than shorter-lived animals, independent of evolutionary distance: shorturl.at/MtgcR

Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post. www.washingtonpost.com/opinions/202...

This should be bigger news, no? www.yahoo.com/news/trump-s...

DeLAURO: Are you planning to break the law by impounding appropriated funds? RFK Jr: If you appropriate the funds, I'm going to spend them D: We have! You're cutting the NIH by $18b. Congress appropriated those funds. How can you justify cutting billions from the biomedical research budget?

Bernie Sanders' office has put out a report this morning on Trump's NIH cuts: "Trump officials effectively cut $2.7 billion in [NIH] funding in the first three months of 2025 – including a 31 percent cut to cancer research through March, compared to the same timeframe last year."

Exclusive: National Science Foundation staff were told today that the agency’s 37 divisions—across all eight directorates—are being abolished and the number of programs within those divisions will be drastically reduced.

Amplifying this. NIH money not used by end of summer is gone. I've had a new R01 pending for months now, the award is prepared (according to ERA commons), what steps are left before the NOGA and funds released? Feel like many grants are being slow rolled before they are then not funded.

This is a great piece. Bhattacharya insisted that the reporter not "write about rumors" because "it spreads panic.” Hours later, those very leads were confirmed. www.science.org/content/arti...

The AAU, the APLU, and ACE and a bunch of named universities (including @cmu.edu) filed a challenge to the arbitrary cut of indirect costs at the National Science Foundation (As I write two NSF proposals...) #SaveNSF #SaveScience www.aau.edu/newsroom/pre...

Heard this story in person from @laurakiessling.bsky.social at a conference and glad to see it out. I really love approaches where I get to say to myself “man I wish I had thought of that”…simple and elegant.

The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n

BREAKING: NSF has frozen all grant funding, as of yesterday. It's unclear when they will resume funding awards, or why the pause has been put in place. www.nature.com/articles/d41...

The president is recommending a 40% cut to next year’s NIH budget. This would be disastrous for our nation’s health and economy. Please contact your representatives, especially if they are Republicans, and tell them why this cannot happen. An easy option: 5calls.org

FYI: The Spencer Foundation, Kapor Foundation, The William T. Grant Foundation, and the Alfred P. Sloan Foundation have collaborated to offer $25K rapid response grants. "This rapid response bridge funding opportunity is for scholars and teams whose grants have recently been cancelled by NSF."

I am late to this but @lastweektonight.com is doing better journalism on the Trump-induced crisis in American public health than most other "real" mainstream media outlets. Watch it, all of it. #RFKMustGo. youtu.be/8H34jcpEsFs?...

"So who voted for this? I personally don't remember Donald Trump's campaign promise to cut breast cancer research and to make menopause harder for American women,” says Chris Hayes on the Trump admin gutting the first and largest women’s health study.

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

Well the NIH has cancelled the Women's Health Initiative, the largest study of women in history It has been running continuously since 1991 and has provided massive key knowledge about diseases in women Unreal www.science.org/content/arti...

Nick Riley receives one of the Biochemical Society Early Career Research Awards for 2026. Congratulations to @nmriley.bsky.social www.biochemistry.org/grants-and-a...

I'm struggling...

Kudos to Seth Rogen for speaking truth to power! 🧪

The leaked Trump administration 2026 HHS budget is sickening. If enacted, it will destroy American science. NIH budget slashed by 40%. The 15% overhead for universities baked into law. Ill-conceived reorganization of NIH institutes.

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

Nature Communications is looking to hire an organic chemist – more details in the link below #Chemsky #Chemjobs 🧪

Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost. www.training.nih.gov/research-tra...

Exclusive: Weeks after President Donald Trump’s administration ordered NIH to pull $250 million in biomedical research grants to Columbia University, the agency is freezing all remaining grant money owed to the university until further notice. scim.ag/4if5Rg1

Had an excellent time hearing about awesome science from Southern California. Thanks so much for the invitation to speak.

Congrats!

NIH is the best investment there is. www.forbes.com/sites/michae...

The situation at Columbia... www.insidehighered.com/news/quick-t... 1/n

Delighted to play a small part in this comment on the potential threats of mirror-image life. Don’t forget about the glycans. #glycotime

The House Continuing Resolution budget “adjustments” for NIH are drastic. Here are some examples:

Cancer research is going to disappear in the US because apparently no one in US leadership ever took a biology class. “DOGE found $8 million grant to make mice transgender. This is real.” - Donald Trump, talking about transgenic mice to the world www.irishstar.com/news/us-news...

Any experienced peptide chemists out there looking for a new challenge? I have an opening on my team vrtx.wd5.myworkdayjobs.com/en-US/vertex...

NIH funding is frozen. @annikabarber.bsky.social is keeping score: 50%+ of study sections planned for this year (77/148) have been cancelled. I talked to Dr. Barber about why these delays are disastrous, and why scientists should be pooling info and speaking up: www.chronicle.com/article/nih-...

“Look, there's no way a Republican Senate and Republican House are going to limit what a Republican president can do.” www.politico.com/live-updates...

Trump's illegal NIH cuts mean cancer researchers would be laid off, sick kids going without treatment, and more. These cuts would be DEVASTATING for lifesaving research. Some Republicans have said they agree—but they just blocked my amendment to reverse Trump's NIH cuts anyway.