Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...

@dmeremin.bsky.social Absolutely crushed it with this automated workflow! It ain’t about the size of your crystals, nor the way that they look, that matters…it’s all about how they diffract! Cheers to the whole team!

🚨Hot off the press @jacs.acspublications.org! Your TEM can now solve crystal structures on its own. Small molecules, materials, proteins—all with one platform: REyes, the first end-to-end autonomous electron diffraction suite doi.org/10.1021/jacs... @caltechcce.bsky.social @uclacb.bsky.social

🚨 3 weeks to go! 🚨 Join us for the 2nd LA Mass Spec Day 🧪✨ 📅 Oct 17, 10am–5pm 📍 UCLA South Bay Campus Plenary talks • Contributed talks • Posters • Networking 👉 Register: lnkd.in/gFdW9rfG 👉 Abstracts: lnkd.in/gb-Qq7d5

Want to know what sets Direct Electron apart? Let our satisfied customers tell you! To learn more about Apollo & our other ultra-fast cameras for Electron Microscopy & CryoEM, visit directelectron.com/products/

🚨Hot @J_A_C_S : Alkyl triflate hydrolysis at air-water interface defies pH extremes 1-13 with an unchanged rate. Diluting water with glycol slows it further. Stay tuned for our collaboration with @jahandawlaty.bsky.social exploring interfacial chemistry doi.org/10.1021/jacs... #ChemSky

Had a pleasure introducing REyes, a fully autonomous, open-source electron diffraction suite at #ACSFall2025. Many thanks to the organizers @olexandr.bsky.social and #CASFutureLeaders for the opportunity #ReciprocalEyes #chrmsky @caltechcce.bsky.social @hoseanelson.bsky.social @nsf-ccas.bsky.social

Start your morning off with a presentation by @dmeremin.bsky.social today at 8:40 AM! More information: acs.digitellinc.com/live/35/sess... #ccas #nsf #chemistry #computerscience #chemsky #ACS

Congratulations, @omarfarha.bsky.social, on your 2025 Inorganic Nanoscience Award! An outstanding achievement and a memorable symposium #chemsky

Still have goosebumps from meeting Dick Schrock at #ACSFall2025! Back in grad school I explored metal-carbene complexes and at every exam or review I was always asked, “Is it a Schrock or Fischer carbene?” Thank you, Dick, for shaping and inspiring so many of us

It's Tuesday morning at #ACSFall2025, and I'd like to thank @redbull.com for sponsoring my daily energy boost

#ACSFall2025 is in full swing. A huge shoutout to @bagphos.bsky.social, Program Chair @organicdivision.org, for putting together the program

#ACSFall2025 hasn't started yet, but chemists are flooding DC streets already. Great to bump into @profhein.bsky.social this morning

Hope is not something I feel frequently right now, so yesterday was a very special day. I had the privilege to spend the day with the #CASFutureLeaders - meeting each of these brilliant scientists who are changing the world through their leadership and outreach was so uplifting and inspiring!

One thing you can always count on in the #CASFutureLeaders program is exceptional training from THE BEST facilitators. Thank you to Christine, Bryan, and Fola from @storycollider.bsky.social and Maggie and Emily from scitrain. Great start to our week in Columbus!

Kicking off the #CASFutureLeaders 2025 program in Columbus with an awesome welcome gift from CAS curated by @petercarlton.bsky.social and Nicole! So excited to have finally met the incredible cohort and can’t wait for the week ahead starting tomorrow with @storycollider.bsky.social

🚨 Save the date! 🚨 2nd LA Mass Spec Day: Oct 17, 2025 @ UCLA South Bay 🎉 Talks, posters, networking + plenaries by Jennifer Van Eyk & Melissa Hoffman! Register 👉 forms.gle/e6A9XWxiRF6K... Submit abstracts 👉 forms.gle/RCf5v3Gab5V8... More info to follow soon

Daily Bruin article about the ~800 frozen grants at UCLA including some from my lab dailybruin.com/2025/08/02/a...

Overdue post, but heartfelt thanks to Kraig Wheeler, Trisha Russell, Michael Ruf & Brian Patrick for the outstanding Pacific Northwest Summer Crystallographic Institute at Whitworth! A deep dive into small molecule diffraction & Olex2. Highly recommended!

Check out the stunning cover featuring recent paper from @hoseanelson.bsky.social Lab, led by our one and only @daverdude.bsky.social! He discovered an entire class of natural products using microED powered by arrayED @caltech.edu @caltechcce.bsky.social @uclacb.bsky.social

On the front cover of this week's issue: "Microcrystal Electron Diffraction-Guided Discovery of Fungal Metabolites" Read it here 🔗: buff.ly/F6E8Ygs #ChemSky #JACS

Excited to share the latest work from David Anderson just accepted @angewandtechemie.bsky.social on the structure and applications of #sodium #neopentyl a donor free #organosodium #reagent soluble in #hydrocarbon solvents @unibe.ch onlinelibrary.wiley.com/doi/epdf/10....

Chem Camp aka #ORPGRC2025 reminded me why this is more than science, it's about community. Grateful to lead a stellar session with talks by @christinemle.bsky.social, Osvaldo, Lin, Antonio & Diana. Special thanks to @kuhokie42.bsky.social & Dave for inviting me!

Such fun week! So great to meet you irl at last. I feel it is a quest now: get a photo all 4 of us with @bagphos.bsky.social and @kuhokie42.bsky.social 🤣

Less than a decade ago, reactions for adding, deleting, and swapping single atoms in complex organic molecules were almost unheard of. Now there’s a growing community of researchers working on them. cen.acs.org/synthesis/Sk... #chemsky 🧪

Give a follow to @ananikovlab.bsky.social for cutting-edge chemistry, catalysis, AI in science, and molecular complexity

Hi! I’m giving a talk about the collaboration I got to work on with @dmeremin.bsky.social at the #CSC2025 conference. If anyone will be there - let me know - and also come see my talk! 😈🤠🇨🇦

One of the unspoken frustrations for many chemists, finally unpacked by my PhD advisor Valentine Ananikov and his team in JACS Au. Reproducibility is everything in science, and this shows why yesterday’s reaction doesn’t always work today A must read: doi.org/10.1021/jacs...

This is just awesome! Congratulations Michael and team!

Congrats Professor Laskin @lablaskin.bsky.social‬ on the review in @natrevchem.nature.com Read more: www.chem.purdue.edu/media/news/2...

Where will you be a year from now? How about the beautiful Lake Michigan beach town - Holland, MI for the 40th Reaction Mechanisms Conference June 7-10, 2026 at Hope College? Our honoree is Peter Chen (ETH Zurich). Come for great science and company! zurl.co/lX2WS

🚀🪐 And it’s a wrap for #ASMS2025! Absolutely fantastic plenary by Melissa Trainer on the NASA Goddard Space Flight Center Dragonfly Mission to Titan. We need more mass specs to explore space. Thank you @asms.org and #TeamMassSpec for a wonderful week and see you next year in San Diego

🚨Hot off the press from @hoseanelson.bsky.social and @yitangucla.bsky.social in @jacs.acspublications.org! Congratulations @daverdude.bsky.social and team! MicroED is a discovery tool and it has just revealed a whole new class of fungal metabolites pubs.acs.org/doi/10.1021/...

Great to see so many new faces at the 2025 C-CAS in person meeting! Special thanks to @cmuscience.bsky.social for hosting us! #ccas #nsf #cmu #chemistry #collaboration

Huge congratulations Livia on the Biemann Medal! So incredibly well deserved. You’ve shown us how far taking risks in mass spectrometry can go. I continue to learn so much from you and your fearless path. #ASMS2025

Happy 20th anniversary of Orbitrap! Congratulations Alexander and @thermofishersci.bsky.social! And of course huge shoutout to Dominique for organizing #ASMS2025

👏🏼 Huge applause to all the speakers today! The Unconventional Approaches in MS session at #ASMS2025 was absolutely phenomenal. We heard cutting-edge updates on reaction monitoring, microdroplet reactivity, acoustic manipulation, and the synergy of MS and microED

Hey #ASMS2025! Are you ready for Day 3? Come join me for the Unconventional Approaches in MS session this morning

The elusive @iondoctor.bsky.social caught me! #ASMS2025

Left-handed or right-handed? D or L? R or S? While mass spec is still working on how to tell enantiomers apart, none of that matters when you’re reuniting with friends at #ASMS2025

Fun starts on Day 0 at #ASMS2025! Warming up with @chopralab.bsky.social on a breezy boat tour of Baltimore Harbor. Big thanks to Agilent for the invite #TeamMassSpec

It’s that time of year again! #ASMS2025 kicks off today. Starting Day 1 with now traditional selfie with @garcialabms.bsky.social 🤳 #TeamMassSpec

Our latest is a serendipitously discovered pair of reactions that can pull either the C2 or C3 carbon out of quinolines by choice of an amine scavenger. A deep mechanistic dive took us some surprising places, in @chemiejisoo.bsky.social's latest. pubs.acs.org/doi/full/10....

Excited to share new work from our customer @dmeremin.bsky.social at Nelson Lab & @caltechcce.bsky.social : REyes enables fully autonomous microED—real-time mapping, crystal ID, and ab initio solutions with no human input using DE’s Apollo camera. Read more: chemrxiv.org/engage/chemr...

What if your TEM could run #microED and solve structures on its own? Just insert your sample—watch the structure appear. No human picks. No manual tweaks. Meet REyes! doi.org/10.26434/che... @caltechcce.bsky.social @caltech.edu @uclacb.bsky.social

A great evening of science for #TeamMassSpec. Many thanks to @amgen.bsky.social for hosting LAMMS Spring Meeting featuring talks by Pavel Bondarenko and @j-my-sci.bsky.social @cedarssinai.bsky.social

Two generations of #CASFutureLeaders ‘18 and ‘25 at #ACSSpring2025! Always great to catch up with you @gabegomes.bsky.social!

Hey #ACSSpring2025! Proud chemists and #CASFutureLeaders @olgaeremina.bsky.social and me are ready to dive into a week of amazing chemistry

Grateful for the incredible mentorship from Hosea, support of the Nelson lab, and the inspiring environment @caltechcce.bsky.social that turns curiosity into discovery and the impossible into reality. Excited for the journey ahead with #CASFutureLeaders ’25!