Alone in lab (this is why you don’t work alone) as a summer worker in a coatings factory. Dropped (and broke) a 2L bottle of Freon-122 Grabbed towels to try and wipe up. Freon vapor is heavier than air. Realized this when I stood up and the room spun Got out ASAP and let the hoods do their job

Introduce yourself with what almost killed you. Freon-122

“Eeyore, pull over, I’m feeling a bit woozle-ly”

President Zelenskyy on Maduro: What can I say here? If this can be done to dictators, like that, then the United States of America know what they should do next.

The next @organicdivision.org Virtual Symposium on Jan 14 @ 12 noon ET ft. Prof. Christian Malapit @camalapit.bsky.social & Dr. Kaid Harper #AbbVieChemistry #Electrochem Free to watch YouTube: orgn.link/watch Zoom: emory.zoom.us/j/18563507 #ChemSky #ChemChat

Pet Peeves: Self checkout at that one store Holding everyone up to back into a spot that you can’t fit into anyway Invading countries to steal oil

4’33” by John Cage You can play it over and over and nobody would ever notice

Chemists in the Wild - a photographic journey #ChemSky 21: Chemist seeing a Texas Carbon in a public artwork

If pasta was data

Welcome 2026. Be better.

N-N coupling through Fe-catalyzed N-H dehydrocoupling! Check out our latest V2 on chemrxiv where we show you can catalyze PCET reactions using mild reagents below the thermodynamic limit of initial H• abstraction, make hard-to-access 2H-indazoles, and even skeletal edit! chemrxiv.org/engage/chemr...

For some excellent timeline cleanse follow my good friend Parag @parag.bsky.social for some amazing astrophotography

A couple of comets made appearances in October. I could capture only Comet Lemon. Its tail kept changing very quickly and can be seen in these two photos taken over 2 days. #astro #astrophotography

My favorite photo from February is of one of my most favorite target - the horsehead and flame nebulae #astro #astrophotography

Forget insults, what’s the most unhinged *compliment* you’ve ever received?

Just in time for the new year - we show that you can make either isomer of N-aryl pyrazole selectively from a single TDSO. We really believe in the power of these wacky heterocycles. chemrxiv.org/engage/chemr... Excellent work by superstar Alex Fanourakis, in collab with Osvaldo Gutierrez and J&J

Thanks ABC - I’m not really interested - I was there - we all were

Paper out today with a transformation a colleague published >10y ago…it is referenced but the new paper has the EXACT same reagents etc - the only diff is a change in solvent and smaller scope. Just poor referee/editor work The same reaction (but missing a key mechanism step) #ChemSky #ChemChat

You've just opened a chemistry themed pub, what are you calling it? Jack’s #chemsky

Now that you have a Chemistry-themed pub, what’s your signature #ChemSky cocktail? Reviewer’s Revenge (Bourbon with way too much bitters)

You’ve just opened a Chemistry themed pub. What are you calling it? The Flask and Column #ChemSky #ChemChat

make a Bond movie academic On The Dean’s Secret Service

I think I know where it’s snowing 🌨️

Jake: Dr. No Thank You

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 12b: I’m so excited how this one turned out with the @sarponggroup.bsky.social led by Philip Speiß. A one-pot fusion of 2 heterocycles - a whole new way in to key 6/5 and 6/6 pharmacophores @jacs.acspublications.org #ChemSky #ChemChat

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 12a: What a pleasure it was to work with the @uwyoongroup.bsky.social and @tehshik.bsky.social on this sp3 skeletal rearrangement paper - wonderful job by Caitlin, Cade and all - I’m still floored by this rxn #ChemSky #ChemChat

The Official Face of Socks at Christmas™

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 11/n: A super cross line/site collaboration among Groton and La Jolla medchem teams with our Process chemists comes this fantastic het synthesis w/ innovative BOCNMe2 zincate coupling #JOC #ChemSky #ChemChat

Meanwhile, on the apparatus at the chemistry olympics. #chemsky #chemchat

Six month exposure in a pinhole camera tracking the Sun's movement from summer to winter solstice. This is so cool - you can spot stretches of cloudy days. Have to redo this to catch the summer sun better. This image was taken using #solarcan

Master of Poutine 🎼Taste me and you will see More is all you need Dedicated to How I'm killing you Master Master of Poutine I'm covered with cheese Gravy and fries, smashing your dreams Looking at me, you can't taste a thing Just call my name, 'cause I'll make you scream Master Poutine 🎵

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 10/n: Alkylation of R-SO2F with carbon nucleophiles out in @chemicalscience.rsc.org - a collaboration with the awesome @ballnchemist.bsky.social and his amazing undergrads at @pomonacollege.bsky.social #ChemSky #Chemchat

Three days till Christmas and if you haven’t managed to find chemistry themed Xmas cards then I have your back. Some labels too🙂 These printable downloads will see you right! #chemsky #chemchat thechemscrapesshop.etsy.com/listing/4389...

🎶there's gonna be a rumble toniiiiiight🎶

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 9/n: An industry collab with our Pfizer La Jolla colleagues (w/BMS+BioGen) and @BaranLabReads comes this wonderful medchem look at sulfonyl hydrazides as powerful sp2-sp3 coupling agents #ChemSky #ChemChat

A Lord of the Rings Cover Band called Helms Deep Purple with their smash hit Smaug on the Water

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 8/n: Room temp catalytic amide formation with this ingenious bifunctional B-P reagent from our process chem in collab with the Sandford Lab @ UTSA #ChemSky #ChemChat

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 7/n: From my colleague Jun Xiao and our MedChem teams in collab with our WuXi partners this is a facile sp2-sp3 Suzuki with tons of het scope using alkyl gem-(bis)boronates #ChemSky #ChemChat

Finally! My kind of health study!

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 6/n: This wonderful review of desulfinative coupling in med chem as an alternative to traditional Suzuki - esp effective for heterocycles - collab with the Willis lab @rhpdcu.bsky.social Uses in PMC to scale up #ChemSky #ChemChat

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 5/n: From Pfizer Boulder-this #OPRD has it all-enablement, sp2/sp3 hets, cross electrophile couplings, SnAr and more - nice work from @ronhinklin.bsky.social and all #ChemSky #ChemChat

I’m not over that Suzuki lost to Grignard By. One. Vote.

#facultychemjobs weather report: stabilizing at 25% off Today (12/16/25), there are 349 tenure-track research/teaching positions and 58 teaching positions for the 2026 Chemistry Faculty Jobs List. 12/17/24: 449 tenure-track, 69 teaching 12/19/23: 481 tenure-track, 60 teaching

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 4a/n: The Copper Crew from our Process chem department teamed up again for another #OPRD paper on Cu-catalyzed coupling this time enabling 2° amines with very mild conditions #ChemSky #ChemChat

Interrupting #12DaysOfPapers to share this beauty from #PfizerChemistry, @mykhailiukchem.bsky.social Enamine, @pengliugroup.bsky.social and a host of Scripps La Jolla folks now out in @natsynth.nature.com - stereocontrolled cyclopropanes from Alkyl-SO2F & olefins with a Pd (II-IV) catalytic cycle

My favorite 2025 #PfizerChemistry publications #12daysOfPapers 4/n: From our Process chem colleagues comes this wonderful #OPRD paper on Cu-catalyzed ammonia/small amine couplings - tons of het scope, easy set up (even worked for me!) #ChemSky #ChemChat

Another one from the boy 🙃 Eddie Van Halogen #chemsky

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My favorite 2025 #PfizerChemistry publications #12daysOfPapers 3/n: MedChem and Process working together to enable chiral cyclopropanes for pre-clinical scaleup - route scouting and development with great teamwork #OPRD #ChemSky #ChemChat