Nature Reviews Chemistry
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A chemistry journal published by SpringerNature .
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Including reviews on: Transuranium organometallics Machine learning for heterogeneous catalysis Medium-sized rings with non-central chirality A Roadmap towards a potent and selective modulator for every human protein by 2035
5 months ago
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A call for chemical safety and sustainability
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00798-8The Stockholm Declaration on Chemistry for the Future, launched during the Nobel Symposium in May 2025, aims to align research, education, industry, and governance with the goal of focusing the future of chemistry on safety and sustainability.
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3 days ago
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Towards effective and ethical GenAI in chemistry education
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00799-7In 2025, chemistry education research moved towards more mature and critical uses of generative artificial intelligence (GenAI). Recent studies show how GenAI can support visualization and learning of abstract chemical concepts, while highlighting the need for strong AI literacy to manage errors, ethics and misuse.
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3 days ago
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A conversation with a chemical biology pioneer
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00803-0Ahead of his 70th birthday, Stuart Schreiber, Morris Loeb Research Professor at Harvard University, discussed his life in science.
http://dlvr.it/TQqMvX
3 days ago
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A call for chemical safety and sustainability
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00798-8The Stockholm Declaration on Chemistry for the Future, launched during the Nobel Symposium in May 2025, aims to align research, education, industry, and governance with the goal of focusing the future of chemistry on safety and sustainability.
http://dlvr.it/TQpfvt
4 days ago
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Towards effective and ethical GenAI in chemistry education
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00799-7In 2025, chemistry education research moved towards more mature and critical uses of generative artificial intelligence (GenAI). Recent studies show how GenAI can support visualization and learning of abstract chemical concepts, while highlighting the need for strong AI literacy to manage errors, ethics and misuse.
http://dlvr.it/TQpKF0
4 days ago
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A conversation with a chemical biology pioneer
Nature Reviews Chemistry, Published online: 06 February 2026; doi:10.1038/s41570-026-00803-0Ahead of his 70th birthday, Stuart Schreiber, Morris Loeb Research Professor at Harvard University, discussed his life in science.
http://dlvr.it/TQp3wx
5 days ago
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Substitution and electrochemistry in layered oxide cathode materials for sodium-ion batteries
Nature Reviews Chemistry, Published online: 29 January 2026; doi:10.1038/s41570-025-00795-3The impact of atomic substitution in sodium-layered oxides and how substitutions affect the properties and performances of battery materials are discussed, with the aim of improving sodium-layered oxides and accelerating the commercialization of sodium-ion batteries.
http://dlvr.it/TQn9wJ
5 days ago
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Stories from the scientist who changed how we visualize proteins
Nature Reviews Chemistry, Published online: 27 January 2026; doi:10.1038/s41570-026-00800-3Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D structure of proteins.
http://dlvr.it/TQkXp9
8 days ago
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Solar fuel technologies have a wide range of operating conditions, this Review from January explores what all the different approaches have in common, and how this can be used to develop the technology further.
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What solar fuel technologies can learn from each other - Nature Reviews Clean Technology
Solar fuel technologies share common working principles of light absorption and charge separation, yet their operating conditions can vary greatly. This Perspective examines key performance metrics and outlines a transversal vision of how these technologies could help to accelerate each other development.
http://dlvr.it/TQjP5L
9 days ago
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Making chemistry compute with non-steady-state chemical dynamics
Nature Reviews Chemistry, Published online: 26 January 2026; doi:10.1038/s41570-026-00796-wNon-steady-state chemical dynamics offer a powerful tool for neuromorphic computing by harnessing nonlinear, collective, and time-evolving behaviours. Coupled with frameworks such as reservoir computing, these systems enable trajectory-based information processing at the molecular scale through concepts from chemical kinetics and far-from-equilibrium dynamics.
http://dlvr.it/TQjJKk
9 days ago
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Substitution and electrochemistry in layered oxide cathode materials for sodium-ion batteries
Nature Reviews Chemistry, Published online: 29 January 2026; doi:10.1038/s41570-025-00795-3The impact of atomic substitution in sodium-layered oxides and how substitutions affect the properties and performances of battery materials are discussed, with the aim of improving sodium-layered oxides and accelerating the commercialization of sodium-ion batteries.
http://dlvr.it/TQgHZV
11 days ago
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The geopolitical future for chemistry
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-026-00797-9In an era of global transition, new frontiers in chemistry — from space mining to circular technologies — are poised to reshape global power. This Comment explores how future supply chains, strategic resources, and chemistry could define the next era of geopolitical competition.
http://dlvr.it/TQfc2g
12 days ago
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First-principles approaches and concepts to simulate electrochemical interfaces
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-025-00792-6State-of-the-art approaches for modelling electrified solid–electrolyte interfaces are critically discussed, highlighting key challenges in incorporating thermodynamic open-boundary conditions, large electrostatic potentials and their dynamic fluctuations into realistic ab initio simulations.
http://dlvr.it/TQfP9p
12 days ago
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Substitution and electrochemistry in layered oxide cathode materials for sodium-ion batteries
Nature Reviews Chemistry, Published online: 29 January 2026; doi:10.1038/s41570-025-00795-3The impact of atomic substitution in sodium-layered oxides and how substitutions affect the properties and performances of battery materials are discussed, with the aim of improving sodium-layered oxides and accelerating the commercialization of sodium-ion batteries.
http://dlvr.it/TQf3v2
12 days ago
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Stories from the scientist who changed how we visualize proteins
Nature Reviews Chemistry, Published online: 27 January 2026; doi:10.1038/s41570-026-00800-3Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D structure of proteins.
http://dlvr.it/TQd18N
13 days ago
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Ion migration in perovskite solar cells
Nature Reviews Chemistry, Published online: 21 January 2026; doi:10.1038/s41570-025-00790-8Ion migration plays a crucial role in perovskite solar cells. This Review covers its mechanisms, impact on device performance and degradation, measurement techniques, and emerging strategies towards controlling ion migration.
http://dlvr.it/TQcSpC
14 days ago
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Making chemistry compute with non-steady-state chemical dynamics
Nature Reviews Chemistry, Published online: 26 January 2026; doi:10.1038/s41570-026-00796-wNon-steady-state chemical dynamics offer a powerful tool for neuromorphic computing by harnessing nonlinear, collective, and time-evolving behaviours. Coupled with frameworks such as reservoir computing, these systems enable trajectory-based information processing at the molecular scale through concepts from chemical kinetics and far-from-equilibrium dynamics.
http://dlvr.it/TQbtc8
14 days ago
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Stories from the scientist who changed how we visualize proteins
Nature Reviews Chemistry, Published online: 27 January 2026; doi:10.1038/s41570-026-00800-3Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D structure of proteins.
http://dlvr.it/TQbgrY
14 days ago
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Programming DNA machines to move
Nature Reviews Chemistry, Published online: 19 January 2026; doi:10.1038/s41570-025-00791-7The development of DNA-based machines is transforming fields such as drug delivery and biosensing. Here, design strategies are discussed and key performance metrics — speed, force generation, efficiency and autonomy — are examined to provide insights into the future of DNA nanotechnology.
http://dlvr.it/TQZd7D
15 days ago
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Making chemistry compute with non-steady-state chemical dynamics
Nature Reviews Chemistry, Published online: 26 January 2026; doi:10.1038/s41570-026-00796-wNon-steady-state chemical dynamics offer a powerful tool for neuromorphic computing by harnessing nonlinear, collective, and time-evolving behaviours. Coupled with frameworks such as reservoir computing, these systems enable trajectory-based information processing at the molecular scale through concepts from chemical kinetics and far-from-equilibrium dynamics.
http://dlvr.it/TQZYDx
15 days ago
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The geopolitical future for chemistry
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-026-00797-9In an era of global transition, new frontiers in chemistry — from space mining to circular technologies — are poised to reshape global power. This Comment explores how future supply chains, strategic resources, and chemistry could define the next era of geopolitical competition.
http://dlvr.it/TQY12j
17 days ago
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First-principles approaches and concepts to simulate electrochemical interfaces
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-025-00792-6State-of-the-art approaches for modelling electrified solid–electrolyte interfaces are critically discussed, highlighting key challenges in incorporating thermodynamic open-boundary conditions, large electrostatic potentials and their dynamic fluctuations into realistic ab initio simulations.
http://dlvr.it/TQXwCn
17 days ago
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loading . . .
The geopolitical future for chemistry
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-026-00797-9In an era of global transition, new frontiers in chemistry — from space mining to circular technologies — are poised to reshape global power. This Comment explores how future supply chains, strategic resources, and chemistry could define the next era of geopolitical competition.
http://dlvr.it/TQWzlG
18 days ago
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First-principles approaches and concepts to simulate electrochemical interfaces
Nature Reviews Chemistry, Published online: 23 January 2026; doi:10.1038/s41570-025-00792-6State-of-the-art approaches for modelling electrified solid–electrolyte interfaces are critically discussed, highlighting key challenges in incorporating thermodynamic open-boundary conditions, large electrostatic potentials and their dynamic fluctuations into realistic ab initio simulations.
http://dlvr.it/TQWlm2
18 days ago
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Ion migration in perovskite solar cells
Nature Reviews Chemistry, Published online: 21 January 2026; doi:10.1038/s41570-025-00790-8Ion migration plays a crucial role in perovskite solar cells. This Review covers its mechanisms, impact on device performance and degradation, measurement techniques, and emerging strategies towards controlling ion migration.
http://dlvr.it/TQW9PB
19 days ago
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Ion migration in perovskite solar cells
Nature Reviews Chemistry, Published online: 21 January 2026; doi:10.1038/s41570-025-00790-8Ion migration plays a crucial role in perovskite solar cells. This Review covers its mechanisms, impact on device performance and degradation, measurement techniques, and emerging strategies towards controlling ion migration.
http://dlvr.it/TQTqmk
20 days ago
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Programming DNA machines to move
Nature Reviews Chemistry, Published online: 19 January 2026; doi:10.1038/s41570-025-00791-7The development of DNA-based machines is transforming fields such as drug delivery and biosensing. Here, design strategies are discussed and key performance metrics — speed, force generation, efficiency and autonomy — are examined to provide insights into the future of DNA nanotechnology.
http://dlvr.it/TQT7YD
21 days ago
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Programming DNA machines to move
Nature Reviews Chemistry, Published online: 19 January 2026; doi:10.1038/s41570-025-00791-7The development of DNA-based machines is transforming fields such as drug delivery and biosensing. Here, design strategies are discussed and key performance metrics — speed, force generation, efficiency and autonomy — are examined to provide insights into the future of DNA nanotechnology.
http://dlvr.it/TQRpfj
22 days ago
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reposted by
Nature Reviews Chemistry
Nature Reviews Clean Technology
22 days ago
This Review explores different thermal treatment methods for removing PFAS from waste streams
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PFAS thermal treatment approaches and enhancement - Nature Reviews Clean Technology
Thermal treatment approaches can remediate solids contaminated by per- and polyfluoroalkyl substances (PFAS), but are energy-intensive and create products of incomplete destruction. This Review discusses these approaches and the use of additives to lower reaction temperatures and drive complete destruction of PFAS.
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Tin, Sn!
Nature Reviews Chemistry, Published online: 08 January 2026; doi:10.1038/s41570-025-00794-4Time flies when you’re having fun, they say. And so it is that we welcome you to the 10th volume of Nature Reviews Chemistry.
http://dlvr.it/TQMRRH
27 days ago
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Tin, Sn!
Nature Reviews Chemistry, Published online: 08 January 2026; doi:10.1038/s41570-025-00794-4Time flies when you’re having fun, they say. And so it is that we welcome you to the 10th volume of Nature Reviews Chemistry.
http://dlvr.it/TQG5xn
about 1 month ago
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Strengthening school–university collaborations
Nature Reviews Chemistry, Published online: 02 January 2026; doi:10.1038/s41570-025-00788-2Chemistry is an experimental science that for many learners only comes alive in the laboratory. But specialized equipment is increasingly out of reach of school budgets. Strengthening school–university collaborations can help to bridge the gap.
http://dlvr.it/TQF3Jd
about 1 month ago
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Tin, Sn!
Nature Reviews Chemistry, Published online: 08 January 2026; doi:10.1038/s41570-025-00794-4Time flies when you’re having fun, they say. And so it is that we welcome you to the 10th volume of Nature Reviews Chemistry.
http://dlvr.it/TQDmTM
about 1 month ago
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loading . . .
Strengthening school–university collaborations
Nature Reviews Chemistry, Published online: 02 January 2026; doi:10.1038/s41570-025-00788-2Chemistry is an experimental science that for many learners only comes alive in the laboratory. But specialized equipment is increasingly out of reach of school budgets. Strengthening school–university collaborations can help to bridge the gap.
https://bit.ly/4jlGYBn
about 1 month ago
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loading . . .
Strengthening school–university collaborations
Nature Reviews Chemistry, Published online: 02 January 2026; doi:10.1038/s41570-025-00788-2Chemistry is an experimental science that for many learners only comes alive in the laboratory. But specialized equipment is increasingly out of reach of school budgets. Strengthening school–university collaborations can help to bridge the gap.
https://bit.ly/4jsvXi0
about 1 month ago
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Biomolecular coronas govern the environmental fate of metal–organic frameworks
Nature Reviews Chemistry, Published online: 02 January 2026; doi:10.1038/s41570-025-00789-1Metal–organic frameworks are increasingly used in environmental technologies, whereby their biomolecular coronas determine their identity, transport, persistence and ecosystem effects. We argue that further research is needed to embed corona considerations into framework systems design and regulation, and we outline the minimal, actionable steps needed to achieve this.
https://bit.ly/3YYy9nD
about 1 month ago
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The role of ionizing radiation-initiated reactions in targeted activation of chemotherapeutics
Nature Reviews Chemistry, Published online: 15 December 2025; doi:10.1038/s41570-025-00779-3This Review explores how ionizing radiation triggers drug release via water radiolysis, detailing reactive species, drug activation mechanisms and strategies for designing radiation-sensitive prodrugs and nanocarriers to enhance chemoradiation therapy with reduced systemic toxicity.
https://bit.ly/4qlsgfY
about 2 months ago
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Lessons learned in linking PROTACs from discovery to the clinic
Nature Reviews Chemistry, Published online: 12 December 2025; doi:10.1038/s41570-025-00784-6Proteolysis targeting chimeras (PROTACs) are an emerging platform in drug discovery with the potential to unlock novel pharmacology and tackle undruggable targets. This Review highlights learnings from the first cohort of clinical-stage PROTACs, which use short, ring-rich linkers, often complemented with one basic centre, to achieve good bioavailability and metabolic stability.
https://bit.ly/4j60u4V
about 2 months ago
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From earlier this year, a Review discussing the effects of the low-carbon energy transition on air pollution and health
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Effects of the low-carbon energy transition on air pollution and health - Nature Reviews Clean Technology
The transition to a low-carbon energy system is expected to have both pollution and health impacts, across multiple scales. This Perspective provides an overview of the factors that determine the scale and distribution of these impacts and outlines potential approaches to including health benefits in decision-making about energy transitions.
https://bit.ly/4aUHUdQ
about 2 months ago
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A career with a natural interest in total synthesis
Nature Reviews Chemistry, Published online: 10 December 2025; doi:10.1038/s41570-025-00787-3Ahead of his 80th birthday, Steven V. Ley, Professor of Chemistry at the University of Cambridge, discussed his career from drawing chemicals by hand to his work generating complex natural product architectures using machines.
https://bit.ly/49eH22m
about 2 months ago
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The role of ionizing radiation-initiated reactions in targeted activation of chemotherapeutics
Nature Reviews Chemistry, Published online: 15 December 2025; doi:10.1038/s41570-025-00779-3This Review explores how ionizing radiation triggers drug release via water radiolysis, detailing reactive species, drug activation mechanisms and strategies for designing radiation-sensitive prodrugs and nanocarriers to enhance chemoradiation therapy with reduced systemic toxicity.
https://bit.ly/4qdbWxW
about 2 months ago
0
3
2
loading . . .
The role of ionizing radiation-initiated reactions in targeted activation of chemotherapeutics
Nature Reviews Chemistry, Published online: 15 December 2025; doi:10.1038/s41570-025-00779-3This Review explores how ionizing radiation triggers drug release via water radiolysis, detailing reactive species, drug activation mechanisms and strategies for designing radiation-sensitive prodrugs and nanocarriers to enhance chemoradiation therapy with reduced systemic toxicity.
https://bit.ly/454QlPV
about 2 months ago
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1
loading . . .
Lessons learned in linking PROTACs from discovery to the clinic
Nature Reviews Chemistry, Published online: 12 December 2025; doi:10.1038/s41570-025-00784-6Proteolysis targeting chimeras (PROTACs) are an emerging platform in drug discovery with the potential to unlock novel pharmacology and tackle undruggable targets. This Review highlights learnings from the first cohort of clinical-stage PROTACs, which use short, ring-rich linkers, often complemented with one basic centre, to achieve good bioavailability and metabolic stability.
https://bit.ly/4aOzJQe
about 2 months ago
0
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1
loading . . .
Lessons learned in linking PROTACs from discovery to the clinic
Nature Reviews Chemistry, Published online: 12 December 2025; doi:10.1038/s41570-025-00784-6Proteolysis targeting chimeras (PROTACs) are an emerging platform in drug discovery with the potential to unlock novel pharmacology and tackle undruggable targets. This Review highlights learnings from the first cohort of clinical-stage PROTACs, which use short, ring-rich linkers, often complemented with one basic centre, to achieve good bioavailability and metabolic stability.
https://bit.ly/4rRyK80
2 months ago
0
3
0
loading . . .
A career with a natural interest in total synthesis
Nature Reviews Chemistry, Published online: 10 December 2025; doi:10.1038/s41570-025-00787-3Ahead of his 80th birthday, Steven V. Ley, Professor of Chemistry at the University of Cambridge, discussed his career from drawing chemicals by hand to his work generating complex natural product architectures using machines.
https://bit.ly/4iRj3K1
2 months ago
0
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0
loading . . .
A career with a natural interest in total synthesis
Nature Reviews Chemistry, Published online: 10 December 2025; doi:10.1038/s41570-025-00787-3Ahead of his 80th birthday, Steven V. Ley, Professor of Chemistry at the University of Cambridge, discussed his career from drawing chemicals by hand to his work generating complex natural product architectures using machines.
https://bit.ly/4aIfdRh
2 months ago
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Redefining peptide chemistry beyond accumulating analogues
Nature Reviews Chemistry, Published online: 01 December 2025; doi:10.1038/s41570-025-00786-4In 2025, peptide research saw the convergence of chemical synthesis and computational modelling. Advances in artificial intelligence-guided design and new macrocyclic and covalent frameworks expanded structural creativity, transforming peptides into programmable molecules with functions beyond traditional design.
https://bit.ly/4pozZd8
2 months ago
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Methods and applications for epoxide C–C bond cleavage reactions
Nature Reviews Chemistry, Published online: 01 December 2025; doi:10.1038/s41570-025-00773-9Epoxides, which readily undergo C–O bond cleavage, also undergo skeletal rearrangements via C–C bond activation. This Review discusses modes of epoxide C–C bond cleavage and their applications, highlighting the mechanistic features which lead to selective bond scission.
https://bit.ly/4oHM7VB
2 months ago
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Organic A-cations in metal halide perovskite photovoltaics
Nature Reviews Chemistry, Published online: 28 November 2025; doi:10.1038/s41570-025-00774-8The roles of organic A-cations in halide perovskite photovoltaics are discussed from a molecular point of view by considering their chemical, lattice and electronic interactions. Prospects for future research directions, opportunities and challenges are also presented.
https://bit.ly/48TQTKO
2 months ago
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Unsymmetric bimetallic centres in metalloproteins and synthetic models
Nature Reviews Chemistry, Published online: 27 November 2025; doi:10.1038/s41570-025-00781-9Unsymmetric coordination environments are prevalent in metalloenzymes. By contrast, most synthetic homogeneous catalysts rely on symmetric ligand frameworks. This Review highlights biological unsymmetric bimetallic centres along with their roles in catalysis and illustrates how intentionally incorporated unsymmetry in synthetic systems mimics nature’s strategies for achieving cooperative and complementary reactivity.
https://bit.ly/4rDn8Fz
2 months ago
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