#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software ✅ Free 🔓 Open Source 🧬 More cloning methods than SnapGene 🤖 Can be automated with python 👨‍🔬 Built by a researcher — for researchers! 👉 Check it out at opencloning.org

Researchers have manufactured organic light-emitting diodes (OLED) on a nanoscale – that’s around a hundred times smaller than a human cell. This not only enables ultra-sharp screens and microscopes, but also opens up entirely novel possibilities for wave optics applications. ethz.ch/en/news-and-...

How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)

And now we have Arabidopsis plants with 8 chromosomes instead of 10 and no obvious phenotypic differences, this week in @science.org #PlantScience Paper here: www.science.org/doi/10.1126/... Perspective here: www.science.org/doi/10.1126/...

Multimodal learning enables chat-based exploration of single-cell data - @bocklab.bsky.social @cemm.oeaw.ac.at @meduniwien.ac.at go.nature.com/3WPGJnW

Tension, suspense, or narrative arc in a story is the stuff that keeps the reader going. But how do you introduce suspense in a scientific article? That is what my latest post is all about. aboutacademicwritingandzo.substack.com/p/how-to-wri... #AcademicWriting #WritingTips #NarrativeArc #Suspense

www.nature.com/articles/s41... Really fabulous work! Animal pigments engineered in bacteria.

Agrobacterium-mediated transformation of plants and fungi is enhanced by plasmid copy number variants go.nature.com/3CdewQS rdcu.be/eNaje

Excited to see our paper online! We combined scMS and scRNA-seq from the same plant cells 🌱 — a step toward true single-cell multi-omics in plants. Overview 👇

Discovery and engineering of the biosynthesis of rotenoids www.nature.com/articles/s44... @natsynth.nature.com

Very exciting to finally see our iridoid cyclase ICYC online @natplants.nature.com! A joined effort with Robin Buell’s lab with Josh Wood generating snRNA-seq, and my student Chloée Tymen performing the initial experiment. #natprod #PlantScience @mpi-ce.bsky.social www.nature.com/articles/s41...

Our new study in Nature Plants maps how "multi-tasking" enzymes in plants transfer nitrogen, a key step toward improving crop N use efficiency. 🌱 Big thanks to our collaborators from Max Planck, Hokkaido Univ, & MSU, and for support from @NSF and @DOE. Learn more: rdcu.be/eFOFN #PlantMetabolism

Beautiful work by Yaereen and former lab member Kevin! Learn more about the anti-cancer compound homoharringtonine and its'biosynthesis in plants here 🌿https://www.biorxiv.org/content/10.1101/2025.08.26.672243v1

The multilayered regulation of aromatic amino acid biosynthesis in plants: Trends in Biochemical Sciences www.cell.com/trends/bioch...

Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.

Protein Structural Phylogenetics academic.oup.com/gbe/article/...

Into natural product biosynthesis & tailoring enzymes? Frustrated by the lack of a dedicated resource to explore their functions? Tired of endless literature searches for reaction info? Meet the MITE database, freely available at mite.bioinformatics.nl. Preprint: doi.org/10.26434/che... (1/8)

Inspired by natural molecular glues, drug hunters are chasing protein–protein interactions with next-gen small molecules tuned for enhanced tissue specificity and reduced toxicity www.nature.com/articles/s41... rdcu.be/eAC91

Couldn't have said it better! Great job @taralowensohn.bsky.social, Will, and Chun! Special thanks to the Gao lab at @stanford.edu #singlecell #plantbiology

A truly enabling new approach by @taralowensohn.bsky.social Will Cody and @sattelylab.bsky.social to probe plant genetics at scale. Single-gene-per-cell delivery coupled to an effective transcriptional selection system www.biorxiv.org/content/10.1...

Ingenane biosynthesis enzymes in @newphyt.bsky.social by @matildeflorean.bsky.social, @carstenschotte.bsky.social from @oconnorlab.bsky.social @mpi-ce.bsky.social in collaboration with Ian Graham lab members. #natprod #PlantScience doi.org/10.1111/nph....

Here, the authors @oconnorlab.bsky.social @mpi-ce.bsky.social uncover the mechanism of epimerization behind uncommon 3R-containing alkaloids in Mitragyna speciosa (Kratom) and study their inclusion in downstream biosynthesis #PlantScience #natprod www.nature.com/articles/s41...

SynBio: it’s what plants crave doi.org/10.1093/jxb/... J Exp Bot Insights article from *Dan Hong Loh* - she discusses the impacts of Rubisco SynBio tool expansions from Archer et al. 2025 (doi.org/10.1093/jxb/...).

Heron is a new intuitive software tool that helps researchers design complex experiments even if they don’t have in-depth technical expertise. 🔗

July Issue. Read FREE: Sequencing historical RNA: unrealized potential to increase understanding of the plant tree of life (see cover); Decoding the evolution of C4 photosynthesis; Transcellular regulation of ETI-induced cell death; & much more www.cell.com/trends/plant... #plantscience

Researchers @emoryuniversity.bsky.social observe #longevity benefit of #psilocybin #psychedelic mushroom news.emory.edu/stories/2025... — extended human skin & lung cell lifespan by 50% — increase aged mice survival by 30% — reduces oxidative stress — improves DNA repair 🧪 #health #science #aging

Want to become a cloning wizard? 🪄 Our latest blog post is packed with hands-on tips for mastering Modular Cloning — advice on how to prepare for the process, handle reagents, high-throughput methods, and more. Start your MoClo quest here: https://twp.ai/4io9Rn

Yes when I was on the board of @cornelluniversity.bsky.social the women profs told us exactly this..and even moreso for the minority profs: minority students flocked to them as role models to ask for mentoring and advice, taking time away from the Prof's own research #womeninscience #womeninstem

SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in Nature Chemical Biology presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/46fMIZd 🧪

'Night science' is what you do when you're not sure what's the question.

Defining and benchmarking open problems in single-cell analysis - @krishnaswamylab.bsky.social @fabiantheis.bsky.social bit.ly/4l8dsiF

Broad application of the ALFA tagging technology for in planta nanobody-based imaging and biochemical characterization of plant proteins #resource #PlantCommunications cell.com/plant-commun...

www.science.org/doi/10.1126/... Robots for precision agroinfiltration. Really cool engineering effort with the biology in mind 👍🏾

A composite universal DNA signature for the tree of life. #DNAbarcoes #DNAsignatures #GenomeSequencing @natecoevo.nature.com www.nature.com/articles/s41...

A catalytically inactive enzyme enables the formation of free indole for plant defense + communication, researchers from @oconnorlab.bsky.social from @mpi-ce.bsky.social report in @natchembio.nature.com ‬ DOI: 10.1038/s41589-025-01943-y www.ice.mpg.de/496511/PR_Fl...

I'm very pleased to present the @cp-devcell.bsky.social Voices on plant model organism: www.sciencedirect.com/science/arti.... While we appreciate the diversity of plant models, one often questions which model is the "best"?

We have developed an entirely new mechanism of action for gene knockdown -> trafficking of targeted mRNAs to the lysosomal, using lysosomal trafficking oligonucleotides (LyTONs)! Published in @chemicalscience.rsc.org Led by Disha Kashyap #chemsky 🧪 pubs.rsc.org/en/content/a...

Next preprint out from my work @oconnorlab.bsky.social @mpi-ce.bsky.social : the discovery or iridoid cyclase in asterids! Thread below. #PlantScience #natprod www.biorxiv.org/content/10.1...

Our latest paper is out in its final form in @theplantcell.bsky.social We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context. Read the full paper at: doi.org/10.1093/plce...

Must read for all who use Nicotiana benthamiana as a platform: “Causes and consequences of experimental variation in Nicotiana benthamiana transient expression” #plantscience www.biorxiv.org/content/10.1...

🔬📊 Comment: A checklist for designing and improving the visualization of scientific data @natcellbio.nature.com www.nature.com/articles/s41...

90% of doing science is being open to new ideas.

Today in Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III & deBz-deoxy-Taxol #SingleCell #secmet 🧬🧪🌾

Finally online and open access! This revised version has a slightly different title and contains a number of additional supplementary figures, mainly in vitro enzyme assays. Kept me quite busy in the lab at the end of last year! #PlantScience #natprod www.nature.com/articles/s41...

Excited to share my new Tansley Review @newphyt.bsky.social on emerging single-cell and spatial omics technologies, many of which are just beginning to be applied in plant biology! Big opportunities lie ahead for the field. [1/n]  nph.onlinelibrary.wiley.com/doi/10.1111/...

Metabolic profiling of Iron Age residues from the oasis of Qurayyah reveals the earliest material evidence for the fumigation of the drug plant Peganum harmala, used for medicinal and hygienic purposes, according to a paper in Communications Biology. go.nature.com/3HhFV6D 🏺 🧪

One more week to apply for a postdoc in the Patron lab, Cambridge. This is a 3-year position to investigate regulatory sequences and engineer gene expression in plants with the aim of optimising yields from metabolic pathways. Read more & apply: tinyurl.com/yvk6dhr9 #PlantSciJobs #PlantScience 🧪

Success in academia often has more to do with luck, patronage and the job market than “hard work”. Good academics acknowledge this. I worked hard, but I was in the right place at the right time on occasion. Historians far more talented than I have fallen between the cracks.

Self-supervised learning of molecular representations from millions of tandem mass spectra using DreaMS - @pluskal-lab.org @iocbprague.bsky.social go.nature.com/4k1n5iC