"Explaining something with the wrong model can be worse than not explaining it at all." www.nature.com/articles/s41...

🎙️ Morgane THION, Collège de France, will talk about "microglia in the developing brain: from colonization to functions" on Monday, 9 February, at 11am at Paris Brain Institute. 👉 More information: https://parisbraininstitute.org/agenda/scientific-lectures-morgane-thion

What if the immune system held a key to brain health ? 🧠 Research by Aleksandra Deczkowska @adeczkowska.bsky.social at the Institut Pasteur shows constant immune–brain dialogue, and how modulating immunity could help prevent or treat neurological diseases.

Tumor-associated macrophages directly stimulate neurite outgrowth, revealing a dual role in enhancing intratumoral nerve growth and promoting neural repair after severe spinal cord injury @cp-immunity.bsky.social www.cell.com/immunity/ful...

Why do so few cancer cells manage to form metastases - and what helps the rare ones succeed? Delighted to share our first publication of 2026 🎉🎉, led by the outstanding @lbejarano.bsky.social 🤩, where we reveal some insights into this - focusing on brain metastasis 🧠🧪🔬 www.cell.com/cell-reports...

A researchers’ propensity for risky projects is passed down to their doctoral students — and stays with trainees after they leave the laboratory go.nature.com/4qvaffO

Multidisciplinary training, over time, produces the highest impact people www.science.org/doi/10.1126/...

Microbes weaponizing secondary metabolites to make rivals vulnerable to phage attack 🧪🦠 www.nature.com/articles/s41...

This #Preprint reports that B6 (but not wild mice) have a truncated PDL2, missing an active intracellular signalling domain: "Surprisingly, in C57BL/6J (B6) mice PD-L2 has only a 5-amino acid intracellular domain, and the same is true for several other laboratory mouse strains" #Immunology

When your PI presents your work

I am thrilled to share our latest work led by @zurisullivan.bsky.social in collaboration with @moffittlab.bsky.social ! We find that the brain encodes distinct, pathogen-specific sickness states across behavior, physiology, neural activity, and gene expression 1/6 www.biorxiv.org/content/10.6...

Come to be our colleague! Center of Paris, excellent facilities, research spanning the whole range of basic and biomedical life science topics, enthusiastic and collaborative colleagues, crème brûlée every Friday... What else could one want?

🔬 Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies 📅 Deadline: Feb 9, 2026 👥 2-12 years post-PhD Apply now 📝 research.pasteur.fr/en/call/crea... #JobOpportunity #Research

Evidence continues building that oxidized lipids drive inflammasome activities in health and disease.  A beautiful study shows a link to multiple sclerosis, with a role for inflammasomes and IL-1 in pathology.  Kudos to the authors on this exciting discovery. www.nature.com/articles/s41...

Excited to share our new preprint: “Local B cell maturation and mast cell regulation of choroid plexus function in early life” www.biorxiv.org/content/10.1... , initiated in the lab by Laetitia Travier and led by the one and only @fakesamir.bsky.social

These are the 10 art classroom rules of Corita Kent (artist, teacher, social justice advocate and nun). They are true for any creative process, especially Rule 8: DON’T TRY TO CREATE AND ANALYZE AT THE SAME TIME. THEY’RE DIFFERENT PROCESSES. (i.e. night science / day science).

Early-life stromal niches orchestrate B lymphopoiesis at the brain's borders https://www.biorxiv.org/content/10.1101/2025.11.27.690844v1

Nature research paper: iHALT unlocks liver functionality as a surrogate secondary lymphoid organ go.nature.com/3M7ctmb

Microglial CLEC7A restrains amyloid beta plaque pathology in a mouse model of Alzheimer's disease alz-journals.onlinelibrary.wiley.com/doi/10.1002/... @alzdemjournals.bsky.social

PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️

Our work out in @devbiol.bsky.social, PDGFra is needed for 🧠 perivascular fibroblast development... ⬇️ perivascular fibroblast = ⬇️ perivascular macrophage...cross-talk? 👀 Led by Hannah Jones @hejcell.bsky.social w/ Kelsey Abrams, Sophia Kim, excited for more projects w/ @fantauzzolab.bsky.social!

We have come a long way. #Pinks

A study with data from ~14 million children shows that COVID19 infection is significantly more harmful to kids’ hearts than the vaccine. Marty Makary falsely alleged that “children died” because from COVID19 vaccine. Whomever told him that failed to account for SARS-CoV-2 infections. Link below.

You and the text you need to trim in order to meet the word limit

Evidence continues to accumulate that mRNA can deliver immunostimulatory innate proteins. www.pnas.org/doi/suppl/10...

Happy to share STORIES out now on Nature Methods STORIES learns cell fate landscapes from spatial tramscripromics data profiled at several time points, thus allowing prediction of future cell states. Led by Geert-Jan Huizing and Jules Samaran www.nature.com/articles/s41... @pasteur.fr

During Alzheimer’s Disease Awareness Month, we honor the millions of individuals & families affected by Alzheimer’s, and the scientists working tirelessly to change its course. Each new finding increases our understanding of Alzheimer’s and brings us closer to a cure. #AlzheimersAwarenessMonth

Just a regular thing at @pasteur.fr cantine.

Immunology as a guide to human relationships #immunology

« … Un Français consomme en moyenne plus de 10 000 animaux au cours de sa vie alors qu’il en utilise indirectement seulement 2,5 en moyenne pour la recherche scientifique et biomédicale … »

💚 Last night, the Institut Pasteur lit up its historic building in green: the color of Phelan‑McDermid syndrome. This rare genetic disorder is linked to developmental & language challenges and autism. It was here that researchers identified SHANK3, the gene behind the syndrome 🧬✨

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

Fwd: Fwd: “I hope this email finds you well”

SHERLOCK4HAT: a CRISPR-RNA test rapidly spots animal trypanosomes, boosting sleeping-sickness surveillance and protecting herds. Led by Institut Pasteur & partners, study in eLife. Details: www.pasteur.fr/en/home/rese...

#PressRelease 🗞️ The oldest workshop for making shell jewellery has been unearthed at the Palaeolithic site of La Roche-à-Pierrot. 🐚 👉 www.cnrs.fr/en/press/old...

“WHERE IS THE SOUL” by Aline Zalko, a set of paintings by a fantastic Parisian painter and illustrator, and a product of some hours of discussion about the brain, mind, soul, brain borders, determinism and so much more. Now displayed @pasteur.fr

Some thoughts on meningeal mast cells inspired by Xinzhong Dong and @jonykipnis.bsky.social recent (and AWESOME) papers. Lead: @fakesamir.bsky.social www.cell.com/trends/immun...

Keep your neutrophils close, but your mast cells closer #immunology

Really interesting study showing learning of tool use in carrion crows! www.cell.com/current-biol...

🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance

Another great paper adding to our understanding of macrophage-neuron interactions shaping myeloid and nerve identity (here via TGFb signalling). Led by @philipp359.bsky.social from Freiburg. Out now open access in @cp-immunity.bsky.social:

I started research for this story, which came out today, more than a year ago. Thanks to all who stuck with me, and shared their thoughts. www.science.org/content/arti...

The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part go.nature.com/45Y9aUQ

So what I though was another catalog of antibodies was actually an issue of NRI with a cover inspired by our article!

France faces unprecedented chikungunya outbreak with first locally acquired cases detected in June - earliest on record. #chikungunya ↘️

🦟 From tropical islands to urban Europe, mosquitoes are adapting - and spreading diseases. Of 3,500 species, only ~100 bite humans, but some, like Aedes albopictus, can transmit dengue, chikungunya or Zika. Understanding vector competence is key to stopping outbreaks. ↘️

the destiny spoke - this summer at @aleksdelab.bsky.social we are preparing some awesome manuscripts! can’t wait to share the data in the fall 😎

"our results indicate that academia pays a price by focusing attention and resources on superstars" Nice to see this supported by data analysis, now. H/T: @cxdig.bsky.social www.nature.com/articles/s41...

29 scholars reflect on their participation in adversarial collaborations: “Rather than producing a clear 'winner,' the most common outcome was a deeper understanding of the problem space through the integration of opposing perspectives” Open Access: doi.org/10.1007/s111... #MetaSci #Methodology 🧪

A timely, argument on why we still animal research now when AI can write songs: