Heterogeneity of late #endosome/#lysosomes shown by multiplexed DNA-PAINT imaging. Quantitative pipeline developed by Charles Bond, Melike Lakadamyali @melikel.bsky.social and colleagues: rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

Not all tissues are alike when it comes to NAD+ #metabolism, and our speaker Eija Pirinen knows all about it... This thursday, usual time and place. See you there?

One year and 3 months into the Bomba-Warczak lab… and we’re celebrating our very first PhD candidate — Tristan! Couldn’t be prouder. Congratulations!! 🎉 @tristanwrong.bsky.social

🚨 Our lab is hiring postdoctoral fellows in two different areas of research: (1) mitochondrial biology and (2) reproductive science. Postings are below, and you can visit bombawarczaklab.com to learn more about what we do! Repro: apply.interfolio.com/183045 Mito: apply.interfolio.com/183230

Travelling to the future again. This thursday, we will be nosy and learn about mitochondria and their friendships.

The MITOscience of tomorrow is back. Three short mitochats presented by Débora Santos Rocha @deborasrocha.bsky.social , Valentin L’Hôte @valentinlhote.bsky.social and Marijana Croon @marijanacroon.bsky.social Visit mitotalks.org for zoom link details. Will you time travel with us?

Really thrilled to have our work on mitochondrial presequence strength out today @jcb.org. We establish quantitative parameters to better define "strong" and "weak" presequences both in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a BBSB graduate student in my lab.

In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation. This thursday, usual time and place. See you there?

MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.

See you all Thursday at MITOchats!! @mitotalks.bsky.social @mito-news.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social

the MITOscience of tomorrow is back.

Article out by @statnews.com profiling the terminated MOSAIC K99 program even though the goals fulfilled what the NIH says are their priorities: www.statnews.com/2025/12/08/t... If you’re at #CellBio2025 coming to the MOSAIC scholar session today at 5:30pm in room 116!

First group conference for the Bomba-Warczak lab #CellBio2025 in Philadelphia! Come find us at poster session today - Molly Healey (P#0705) and tomorrow @tristanwrong.bsky.social (P#1257), and at the spotlight session on the now terminated NIH MOSAIC program tonight at 5:30pm.

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

Happy Halloween from the Barbie-Warczak lab 💪💅🎃 @tristanwrong.bsky.social

"Keeping mitochondria fit: Crosstalk between biogenesis and redox pathway" Happening now: link to join psu.zoom.us/j/95127917611 www.mitotalks.org

The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

Hello world! Today’s officially the first day of the lab! It’s an empty space currently only filled with ideas (that I don’t have card access to yet 😂) but I’m excited for the science that will happen here! -JCG

So proud to be a part of this amazing morning. Location ocean beach San Francisco #nokings

Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵 www.biorxiv.org/content/10.1...

Congratulations to Drs. Lynch, Burslem, Marmorstein, Yi-Wei, and the entire research team on the publication of your latest research article in the newest issue of Science magazine! | Science www.science.org/doi/10.1126/...

📢 New preprint alert! We watch ATP, the energy currency, in tiny compartments of brain synapses to show that synapses talk to their local mitochondria to produce energy right when needed during plasticity, required for memory formation: www.biorxiv.org/content/10.1...

Launching a new lab in today’s climate has been anything but smooth sailing—but today, we celebrate a major milestone! I’m absolutely thrilled to welcome not one, but two incredible graduate students to the lab! 🙌 Welcome Tristan and Molly! www.bombawarczaklab.com/lab-members/

Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...

My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...

The Rutter Lab is attending ASBMB! If you are interested in cell metabolism, check out Jared, @queren-alcantara.bsky.social and @luisci22.bsky.social research talks in the sessions below. See you in Chicago! @hhmi.org @uofubiochem.bsky.social @bwfund.bsky.social @cziscience.bsky.social

My quote of the day "Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less." Maria Salomea Skłodowska-Curie (Marie Curie) First female Nobelist, 1st person to win 2 Nobels, and only person to win Nobels in 2 scientific fields.

Thrilled to announce that the registration for the EMBO workshop „Mitochondria in the Nervous System“ is now open. Join us from Sep 29th to Oct 2nd in beautiful Engelberg, Switzerland! meetings.embo.org/event/25-mit...

NIH MOSAIC program’s termination is a massive loss for the next generation of scientists, threatening the research workforce’s future and human health. We remain committed to supporting MOSAIC Scholars with critical resources for the remainder of the award and beyond. Full statement: buff.ly/TSMrvXq

The termination of the NIH MOSAIC program is a critical loss. As one of the 5 societies supporting MOSAIC scholars, ASCB remains dedicated to supporting early-career scientists & broadening the biomedical workforce. We'll continue our mentorship & development efforts through the end of the grant.

regarding Columbia University, I just learned about this (anonymous) account of negotiations of the Hitler regime in the 1930s with Frankfurt University -- Germany's most prestigious university at the time:

Still optimizing further, but so far I'm blown away by the images we can get of an entire intact cochlea in just ~15 minutes with lightsheet microscopy. Sample prep and imaging by Xiaobo Wang and Julien Cicero.

REGISTRATION OPEN for @faseborg.bsky.social Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair | June 1 - 5, 2025 | Nashville, Tennessee. Apply before it is too late: events.faseb.org/event/mitoch... Please re-post!

More white coats, less white robes! @eddpasquier.bsky.social #standupforscience #standupforscience2025

Thank you! I, too, am shocked that so many are so quiet as if they think it will protect them from the worst of this. I don't think it will.

We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country. This Friday, where will you be? standupforscience2025.org

Although we are not federally funded for this summer, WE WILL STILL RUN The National Summer Undergraduate Research Project (NSURP) in 2025. We remain committed to the work that needs to be done and will continue to meet people where they are. 1/4 nsurp.org

Time for some mito-business. Or should we say methyl-business?? Let's ask our speaker Thomas MacVicar. This thursday, usual time and place.

The nanodrop said I had no DNA, but I did the cloning anyway and it woooOoOooorked

I’m celebrating tonight with my father in law, Jack Strominger, who is about to enjoy his 100th New Years! He wants to know whether any other scientist has published in their 100th year. He’s proud to have a paper in the works. I told him you all would know! Please RT

I’m honored and thrilled to join the Keystone Fellows Class of 2025! No better way to kick start the new year in the new lab I get to call my own 🤩 #KSfellows https:// keypoint.keystonesymposia.org/home/keypoint-newsletter-introducing-the-new-fellows-class-of-2025

🧪 Join us for a lesson in how to look at your spectra from Sue Weintraub! Using examples from her research, Sue will highlight the importance of looking at mass spectra and teach you how to get started. You won't want to miss it! Register now: ow.ly/P8fw50UrX6m

It's time 🙃!! The soon-to-be-open Bomba-Warczak Lab at UPenn is HIRING postdocs! If you're interested in mitochondria, proteomics, neurons and/or oocytes, and want to join a young & vibrant lab in a vibrant city - apply 👉 www.bombawarczaklab.com/people/now-h... #TeamMassSpec #mitochondria

Doing 3D-EM in the Lab. can someone please tell me what these structures are? We are imaging the deep cerebellar nuclei here. Please share, I would really like to know.

📣Thursday 1700 CET / 1100 ET Link at www.mitotalks.org

T - 23 days !! @uofpenn.bsky.social

As you're planning out your ASCB schedule be sure to attend the organelle-focused special interest group hosted by @nieminm.bsky.social and myself Mon. 12/16 at 5pm Come hear a fantastic lineup of speakers including @walterwchen.bsky.social @themitotracker.bsky.social @lianjiejerrywei.bsky.social

Mark your calendars: Still finalizing details but I’m putting together an “EVERYBODY’S IN SAN DIEGO!” pre-ASCB workshop at UC San Diego on Friday December 13th from ~10-5:30. This workshop will highlight leaders in cryoEM/ET, mass spec, and light microscopy and AI. Registration link to follow soon.

2025!!