Jonathan Friedman
@labfriedman.bsky.social
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Associate Professor in Cell Biology at UTSW, studying how organelles are shaped and organized
reposted by
Jonathan Friedman
Nils Burger
3 months ago
Excited to share that we are hiring a research assistant for my lab at UTSW in Dallas (www.nils-burger-lab.com). Please share with your mentees.
utsw.taleo.net/careersectio...
We are also looking for motivated, curious, and enthusiastic postdoctoral fellows!
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Research Assistant I, Pharmacology
Click the link provided to see the complete job description.
https://utsw.taleo.net/careersection/2/jobdetail.ftl?job=901577
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Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!
5 months ago
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Does anyone have a favorite mNeonGreen antibody that works well for western and IPs?
5 months ago
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reposted by
Jonathan Friedman
Natalie Niemi
8 months ago
Finally, we find that presequence strength influences yeast metabolism in a model of COX4 deletion. When fused to a leaderless COX4, only presequences that promote “strong” import behavior restore respiratory growth to wild-type levels. 8/n
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reposted by
Jonathan Friedman
Natalie Niemi
8 months ago
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented
@washubbsb.bsky.social
graduate student Youmian Yan. A đź§µ
www.biorxiv.org/content/10.1...
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Mitochondrial presequences harbor variable strengths to maintain organellar function
Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...
https://www.biorxiv.org/content/10.1101/2025.05.26.655807v1
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reposted by
Jonathan Friedman
Natalie Niemi
9 months ago
Niemi lab and
@washubbsb.bsky.social
graduate student Youmian Yan gave a fantastic presentation on her work at the
@asbmb.bsky.social
meeting in Chicago!
#ProudPI
(photo credit to
@kerikozul.bsky.social
)
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reposted by
Jonathan Friedman
Michael Lazarou
10 months ago
This is a very sad day. Shock, despair, disappointment, disbelief... These only scratch the surface in describing this decision and how I feel. I began my career in Parkinson's research in Richard's lab. What happens now to all the trainees still there?
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reposted by
Jonathan Friedman
Natalie Niemi
10 months ago
Come to St. Louis this summer for the United Mitochondrial Disease Foundation MitoMed 2025 Conference! We have a fantastic line up with lots of opportunities for short talks. We're also running a Masterclass for Early Career Investigators. More info here:
www.umdfconference.org
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UMDF Conference
https://www.umdfconference.org/
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Reminder to join us tomorrow at 12pm ET!
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10 months ago
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Join us March 26th at 12pm ET -
@asbmb.bsky.social
LRD seminar series. We have two great mitochondria-focused lipid talks planned from
@jasoncasler.bsky.social
from
@lllackner.bsky.social
's lab and Kailash Venkatraman from
@ibudin.bsky.social
's lab. Register here!
www.asbmb.org/meetings-eve...
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Lipid Research Division Seminar Series
March 26, 2025 | 12 p.m. Eastern
https://www.asbmb.org/meetings-events/lrd-seminar-series
10 months ago
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Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now
@currentbiology.bsky.social
! Led by fantastic
@madeleinempavey.bsky.social
!
www.cell.com/current-biol...
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Compositionally unique mitochondria in filopodia support cellular migration
Marlar-Pavey et al. determine that a subpopulation of compositionally unique mitochondria, METEORs, dynamically localize to filopodia. Loss of mitochondrial targeting to filopodia correlates with a re...
https://www.cell.com/current-biology/fulltext/S0960-9822(25)00125-3
11 months ago
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An excellent opportunity!
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11 months ago
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reposted by
Jonathan Friedman
12 months ago
It’s so nice to be able to celebrate something this week. Newest work from the group! How are nuclear contents delivered to the cytosolic autophagy machinery while maintaining nuclear integrity? Nuclear envelope gymnastics! Cool role for Dnm1/Drp1.
www.nature.com/articles/s41...
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A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope - Nature Cell Biology
Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for d...
https://www.nature.com/articles/s41556-025-01612-1
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reposted by
Jonathan Friedman
Beck Laboratory
about 1 year ago
In a great collaboration with
@hummerlab.bsky.social
and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell:
authors.elsevier.com/sd/article/S...
@mpibp.bsky.social
@uniheidelberg.bsky.social
A thread below:
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A big congrats to Alia on a successful thesis defense!
@themitotracker.bsky.social
gave an excellent talk and did the lab proud! 🥳🎉🍾
about 1 year ago
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reposted by
Jonathan Friedman
Journal of Cell Biology
about 1 year ago
New:
@themitotracker.bsky.social
et al. from
@labfriedman.bsky.social
identify a mitochondrial inner membrane protein that marks and facilitates a subset of sites of mitochondrial fission in human cells.
rupress.org/jcb/article/...
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Looking for some holiday reading material? Our latest paper identifying a new player in mitochondrial fission is now out
@jcellbiol.bsky.social
! A wonderful early present to see this now online!
rupress.org/jcb/article/...
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Functionally conserved inner mitochondrial membrane proteins CCDC51 and Mdm33 demarcate a subset of fission events | Journal of Cell Biology | Rockefeller University Press
Edington et al. determine that Mdm33 and CCDC51 are functionally conserved mitochondrial inner membrane proteins that are required for normal mitochondrial
https://rupress.org/jcb/article/224/3/e202403140/277181/Functionally-conserved-inner-mitochondrial
about 1 year ago
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reposted by
Jonathan Friedman
Suliana Manley
about 1 year ago
I’m ultra excited about our preprints on mitochondrial pearling. In two concurrent collaborative studies with
@wallaceucsf.bsky.social
, we investigated its consequences on mtDNA nucleoids (led by
@jclandoni.bsky.social
) & its biophysical causes (led by
@gavsturm.bsky.social
). Funders HFSP, ERC, SNSF
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reposted by
Jonathan Friedman
Journal of Cell Biology
about 1 year ago
Our executive editor with Alia Edington
@themitotracker.bsky.social
from
@labfriedman.bsky.social
, winner of the 2024 Alan Hall Travel Award! 👉 Be sure to catch Alia's talk today at
#CellBio2024
! Read about his year's winners:
https://buff.ly/4gtpqRk
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reposted by
Jonathan Friedman
Alia Edington
about 1 year ago
Excited to announce that I was awarded the Alan Hall Travel Award from
@jcellbiol.bsky.social
to attend
#CellBio2024
this weekend! If you're attending this year, please join me at my poster or my talk (details below) to learn about my story on novel mediators of mitochondrial dynamics!
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Congrats Alia! 🎉🎉 Well deserved!
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about 1 year ago
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So proud of Alia Edington
@themitotracker.bsky.social
for winning the JCB Alan Hall Travel award to attend ASCB! Thank you
@jcellbiol.bsky.social
for recognizing the hard work of our trainees! Be sure to check out Alia's talk 5pm Mon. in the organelle subgroup or at poster B143 Sun. 11:15!
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about 1 year ago
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As you're planning out your ASCB schedule be sure to attend the organelle-focused special interest group hosted by
@nieminm.bsky.social
and myself Mon. 12/16 at 5pm Come hear a fantastic lineup of speakers including
@walterwchen.bsky.social
@themitotracker.bsky.social
@lianjiejerrywei.bsky.social
about 1 year ago
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Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!
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about 1 year ago
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