Valentin L'Hôte (@valentinlhote.bsky.social)

The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions Abstract. The incorporation of ribonucleotides (rNMPs) into the nuclear genome leads to severe genomic instability, including strand breaks and short 2–5 b https://academic.oup.com/nar/article-abstract/doi/10.1093/nar/gkaf475/8158034?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email