Henceforth, I will be describing the way that U.S. men’s hockey spectacularly squandered good will, brand recognition, and fan loyalty as “pulled a Target.” They pulled a Target.

It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines. apnews.com/article/mode...

After being held in two of them as a boy, I fought for decades urging America to never again build concentration camps and put human beings in them. It breaks my heart to watch this happen twice now in my own lifetime.

A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.

Abolish ICE. Arrest and try them all, starting with Noem

Special Counsel Jack Smith in his Opening Remarks:

Jack Smith: "My fear is that we have seen the rule of law function in our country for so long that many of us have come to take it for granted. The rule of law is not self-executing. It depends on our collective commitment to apply it."

I just woke up from a nap and somehow while I was asleep, everyone on the bus has figured out we are not going to the right place

Prime numbers 2-4999, animated with ggplot2+gganimate. #Rstats code: gist.github.com/stephenturne...

If I was the commander in chief of the Imperial hegemon I would simply not dismantle the network of military and diplomatic alliances, favourable trade deals, and broad cultural paramountcy that had made my nation the most wealthy and powerful the world has ever seen.

Going to tell my kids this is Heat Miser #TheTraitors

Me casting resurrection magic to get up for work this morning

Iran has been under communications blackout for over 60 hours now. Several thousand people have been killed (numbers vary by source, I have seen between 2 and 5000 this morning). Iranians abroad don't know if their loved ones are alive or dead, have absolutely no way to communicate 1/

The sensible thing to do next week would be to return to work with a can-do attitude, value teamwork and leverage synergies to contribute to the value stream, but fucking hell there must be a better way to spend this limited time on earth

Something a little different for this pre-holiday weekend, as we roll towards the end of the year. I did this as part of my MSc thesis, to add a little variety to my hobby of "staring at molecules." #compchem Code is on GitHub at: github.com/amacbride/sk... Enjoy! Have a great holiday.

The cultural impact of Rob Reiner cannot be understated. Legend isn't big enough a word. It goes to 11. You can't handle the truth. As you wish. I'll have what she's having. I'm your number one fan. You guys wanna see a dead body? The very idea of a bucket list. The West Wing. All from his movies.

Steve isn’t here anymore, but he always posted this picture on Hanukkah so I thought we could carry on his tradition and remember him.

imagine trying to convince me that I should "get used" to AI bc it's "here to stay." honey mitch mcconnell has been my senator since before i was born, do you think i don't know how to lock in and hate for the long haul

I guess it's fitting that it's a reimagined, worse version of someone else's artwork

What’s the difference is between an astronomer and an astrophysicist? If you’re on a long-haul flight and the person in the next seat asks what you do, you tell them you’re an astronomer if you want to spend the next 4 hours talking to them, or an astrophysicist if you want to get some sleep. 🔭

It still boggles my mind that AWS took a perfectly useful batteries-included distro like Amazon Linux (1/2) and completely neutered it.

A bit of personal news: I found out this morning that my MSc dissertation was accepted!

Being curious in a universe that seems indifferent to our existence is such a cosmic flex. Laughing, loving, and learning as ephemeral beings in the void, in open rebellion to a world that wants us dead, is so beautifully human. Science as gallows humor, lol.

Perfect Tom Stoppard story from DTel obituary: His response to a letter from Harold Pinter canvassing support for a proposal to have the Comedy Theatre in London rechristened the Pinter Theatre, “Have you thought, instead, of changing your name to Harold Comedy?”

The day after Thanksgiving break. Time to take stock. Am I really going to make a dent in this to-do list before leaving for Christmas/New Year vacation? What do you say, 8-ball?

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n

The 2025 Atlantic Hurricane Season officially ends today. Overall, it was a slightly above-average season with some strange characteristics. [1/4]

That's the story. Nothing else matters.

words, what do they mean www.washingtonpost.com/health/2025/...

Prof. Laura Dassama (Stanford Chem) is developing a small-molecule therapy for sickle cell disease that removes BCL11A, restoring fetal hemoglobin without gene editing. Her goal is a simpler, more affordable sickle cell therapy. brnw.ch/21wXP8k

When there was that *one year* long ago when we forgot to get the turkey bag…

Rate your score on Factor Fexcectorn. Well done, Scientific Reports. pubpeer.com/publications...

TorchSim continues its growth aiming to be the high-performance engine for MLIP-powered atomistic simulation. With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.

Can’t believe the whole country has to suffer through the return of Dickensian childhood diseases because the worst, most ignorant attention-demanders decided other people’s expertise makes them feel bad

Complex de novo structural variants are an underestimated cause of rare disorders www.nature.com/articles/s41...

I can’t believe this monumental paper has finally been published! Congrats to all the very many brilliant researchers involved, including @molecularxtal.bsky.social and @jrkermode.co.uk 😃 What an exciting step in computational chemistry this represents! pubs.aip.org/aip/jcp/arti...

I had the option of getting this comp chem book as a physical book or an eBook. Normally I read pdfs on Kindle, and the eBook cost less, so I went with that. They have now sent me a link to an awkward, locked-down platform called VitalSource. I have regrets 😂 I'll know for next time...

That fable about the scorpion and the frog comes to mind right now...

Rep. Yassamin Ansari has set up a table and this sign outside Speaker Johnson’s office.

Work published today in @natbiotech.nature.com from Arc’s Luke Gilbert and Patrick Hsu labs presents a new way to insert large DNA sequences into the genome using engineered recombinases that don’t require DNA cutting or rely on the cell's repair machinery.

A thread about keeping one’s head above water under the current conditions and not being incapacitated by rage, fear, despair or some mixture of those (1/11)

I have been loudly, persistently anti-Trump since the beginning. And tonight's election results just make me more sure: *there are more of us than there are of them* A good hard look at Trumpism in action has made that impossible to ignore. Let's take this country back, and let's make it better.

And another one is out: a crystallographic and fundamental solid-state study of size-dependent properties in porous materials. A fun adventure that required quite a bit of coding - learned a lot in the process! pubs.acs.org/doi/10.1021/...

About a strange and whimsical form of... art? www.skeptophilia.com/2025/11/chas...

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