Marius Lemberg (@marius-lemberg.bsky.social)

Reactive oxygen species control protein degradation at the mitochondrial import gate This work identifies reactive oxygen species released by the electron transport chain as sentinel molecules that regulate localized protein degradation at mitochondrial TOM complexes, a mechanism that controls mitochondrial protein import and adjusts the abundance of the electron transport chain to cellular needs. https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00909-2