Open postdoc position in immunology focusing on ILC3s and gut immunity at UMass Chan! careers-umms.icims.com/jobs/49293/p...

At what point do we simply call these cells a subset of ILC3? They are more similar to ILC3s developmentally, phenotypically, and functionally than to DCs anyways. www.science.org/doi/10.1126/...

Wow this is a seriously serious supplementary figure from @cellpress.bsky.social today. Panels A through UU. I get that Cell likes to minimize the number of supplementary figures. But is this really what is happening here? www.cell.com/cell/fulltex...

Microglial cGAS-STING-TBK1 activation in paraventricular thalamus mediates sleep and emotional disturbances in lupus mice www.sciencedirect.com/science/arti...

'We also show that LOY in T cells in the TME can affect cancer mortality in patients. Given the prevalence of LOY in healthy older men, these findings may also have implications for tumour-infiltrating T cell & chimeric antigen receptor T cell therapies.' #Immunology #Immunotherapy

'Now, a report by Gustafsson et al. in Nature Biotechnology has identified a subset of thymic mesenchymal cells (ThyMCs) that drives thymic regeneration and harnessed these cells to restore immune function in mice after hematopoietic stem cell transplantation.' www.nature.com/articles/s41...

Feel better during the day than at night during #influenza? Find out the “Role of IL-10 signaling in the #circadian control of host response to influenza infection” www.mucosalimmunology.org/article/S193...

Therapeutic VEGFC treatment protects against traumatic brain injury-driven tauopathy pathogenesis @cp-cellreports.bsky.social www.sciencedirect.com/science/arti...

A paper in Nature reports that mRNA vaccines targeting SARS-CoV-2, COVID-19, also sensitize tumours to immune checkpoint inhibitors. #medsky 🧪

Review @natimmunol.nature.com Antigen-presenting cells as arbiters of mucosal tolerance and immunity www.nature.com/articles/s41...

1/6 With recent excitement around the #NobelPrize announcements, I think it's worth thinking about what the prize will look like in the future, especially for physiology and medicine. What happens when there’s nothing left to discover in medicine? Have we already picked the low-hanging fruit?

Tregs have been one of the central pillars of the field of immunology. It was only a matter of time before these contributions won the #NobelPrize. Much deserved! www.nature.com/articles/d41...

The fact that public funds are used to publish publicly funded research in journals owned by private publishers, who then sell access to that research at ridiculous prices to entities that buy it with more public funds, is kind of insane.

"The bill approved today by the Senate Committee on Appropriations includes $47.2 billion for NIH’s base budget, or about 1% more than this year." www.science.org/content/arti...

"The U.S. Department of Health and Human Services (HHS) today announced the beginning of a coordinated wind-down of its mRNA vaccine development activities...." cc: Sen. Bill Cassidy

Genome Sciences is looking for a Director of Departmental Computing. This is a rare opportunity for someone interested in leading our excellent IT team, building and maintaining computational infrastructure, and working closely with our faculty and labs uwhires.admin.washington.edu/ENG/candidat...

Utility of transgenic hematopoietic stem cell to generate a self-renewing source of tumor-specific cellular immunotherapy in human participants @natcomms.nature.com www.nature.com/articles/s41...

🎉 New paper alert. We benchmarked Visium, GeoMx, and Chromium for FFPE tumor analysis. Thanks @estellayixingdong.bsky.social for pushing this forward, & MOSAIC collaborators! 📄 www.nature.com/articles/s41... #SpatialTranscriptomics #CancerResearch cc: @owkin.bsky.social @10xgenomics.bsky.social

Congrats to Wenqing on another wonderful paper that came out today in #Immunity! www.sciencedirect.com/science/arti...

Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz Mélanie Deschasaux Rebekka Lambrecht rdcu.be/epret

Congrats to my good friend Shruti Sharma! STING, provides essential protection against blood-brain barrier breaches and neuromotor deficits during physiological aging @cp-cellreports.bsky.social cell.com/cell-reports...

Postdoc positions available studying how niche cells drive GI diseases! robertsinstitute.weill.cornell.edu/faculty/goto...

'However, we now report that food-specific pTreg cells are exclusively induced by the recently identified RORγt APCs4–8 and not by cDCs. Instead, our data suggest that pTreg–cDC1 interactions in steady-state limit the expansion of food-specific CD8αβ T cells.' www.nature.com/articles/s41...

50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science. Scientific discoveries and training of our next generation of scientists and engineers are halved. How is that helping the US?

Start your week off with the latest episode of the Mucosal Immunology Podcast @societymucosalimm.bsky.social featuring @priyadevarajan.bsky.social with @marionbrunck.bsky.social @ashu-mangalam.bsky.social and more: open.spotify.com/episode/3dJF...

Article in Press AND Open Access! "Cell therapy with human IL-10-producing ILC2s enhances islet function and inhibits allograft rejection" by Colpitts et al. doi.org/10.1016/j.aj... @sarahcolpitts.bsky.social @sarahcrome.bsky.social #celltherapy #islettransplantation

I’m a dentist from India. The fluoride debate in the U.S. horrifies me I’ve seen what happens when children grow up with unfluoridated water buff.ly/25koX2u

Our paper @hakonjon.bsky.social (missing other colleagues from Bluesky!), Sequence diversity lost in early pregnancy, was published in Nature (@nature.com) today www.nature.com/articles/s41...

Targeting symbionts by apolipoprotein L proteins modulates gut immunity @nature.com www.nature.com/articles/s41...

'CD8 T cells reactive to mis-splicing-derived neoantigens exist in the per. blood of patients w spliceosomal mutant leukemias. However, these T cells have defective NFκB proinflammatory pathways, which might explain why these cells are unable to mount effective antigen-reactive immune responses'

1/ Truly excited to share our new study that I had to privilege to co-lead during my PhD alongside great friends and collaborators @masashi-nomura.bsky.social, @kevin-johnson.bsky.social and Luciano Garofano, published at Nature Genetics @natureportfolio.nature.com! www.nature.com/articles/s41...

Dear mucosal immunologists! Registration for the European Mucosal Immunology Group (EMIG) meeting in Aachen, Germany is now open. Register and see you this July in Aachen! 👇🏼 emig2025.de @petterbrodin.bsky.social @wiag.bsky.social @mucosalimmunol.bsky.social @societymucosalimm.bsky.social

Important message. Also important to remember that federal funding for science isn’t “given” to university laboratories - it is awarded based on highly competitive process, profs spend months/years on proposals that are reviewed by experts, most are rejected. www.young.senate.gov/newsroom/pre...

Amped to share this masterclass of a paper spearheaded by @waisenberg.bsky.social, out today in Immunity. Will et al. provide a deeply detailed look into microglia dysfunction in Krabbe disease & show that microglia replacement therapeutically improves disease outcomes! www.cell.com/immunity/ful...

👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease? 🤰🏽 By vaccination in #pregnancy! Here we review… 💉 Established campaigns vs whooping cough, flu, COVID 💡 New approaches to RSV, GBS 🌈 Future challenges, opportunities #ReproSky #ImmunoSky #IDSky

#pregnancy #microbiome #health Prenatal amoxicillin antibiotic significantly disrupts gut microbiota in offspring, leading to M1 microglial polarization and depressive behavior. Lachnospira (increased by UVB/sunlight) reverses these neurotoxic effects. . www.sciencedirect.com/science/arti...

B cells modulate lung antiviral inflammatory responses via the neurotransmitter acetylcholine www.nature.com/articles/s41...

NIH freezes funds to Harvard and four other universities, but can’t tell them | Science | AAAS www.science.org/content/arti...

Researchers at Columbia will now have to receive prior approval from the NIH before spending their grant money. This will cause significant disruptions, but it seems like it's still just the beginning. Many more institutions will likely be targeted. www.science.org/content/arti...

I could literally quote every single sentence of this commentary, so I'm not going to - just read the whole thing. And thanks, Dr. Bieniasz, for saying it as it is and showing true leadership. We need that from more scientists and scientific leaders. www.theguardian.com/commentisfre...

I love paying TurboTax a few hundred bucks every year to figure out how much money I owe the government, which the government already knows, but won't tell me because TurboTax pays legislators to keep the government from telling me. 😻

Check out this new & exciting #postdoc program from Max Planck Society 🤩 - My lab is thrilled to move to MPI MB in Muenster - positions available in #chromatin #mechanobiology #cancer #stemcells #transcription join us!

A paper in Nature Medicine describes a potential new biomarker for predicting future cognitive resilience versus decline among people with early Alzheimer’s disease. #Alzsky 🧪

>1900 members of the National Academies of Science, Engineering & Medicine issued a statement supporting science for the benefit of all citizens, and ... 1/2 docs.google.com/document/d/1...

The economists get it, maybe someone listen to them if not to us scientists? www.nytimes.com/2025/03/31/b...