For #FluorescenceFriday✨ Exploring the beauty of the locus Coeruleus using IF staining: neurons🔵 surrounded by glowing astrocytes🟢 embracing delicate blood vessels🔴, alongside striking pTau signals💗. A vivid reminder of the cellular complexity shaping brain health and disease. #LC #Neuroscience

Excited to share this new work from the lab, in collaboration with @jtuscher.bsky.social & Rob Sorge! Here, we used single cell transcriptional profiling to define molecular adaptations induced by chronic pain and opioid experience, which often occur in conjunction. www.biorxiv.org/content/10.1...

A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions. Lots of updates from the preprint!

Excited to be co-chairing this @acnporg.bsky.social panel with chair @kr-maynard.bsky.social on opioid-responsive subpopulations in brain reward circuits. Special thanks to @rphillips3.bsky.social for helping to assemble the panel!

Super excited to share this work & accompanying data resources in collab with @martinowk.bsky.social @stephaniehicks.bsky.social @alexisbattle.bsky.social! Congrats to all coauthors and big shout out to @svitlana-bach.bsky.social @prashanthi-ravi.bsky.social for leading this NIDA-funded project.

For #FluorescenceFriday - image from Research Associate Kelsey Montgomery in @kr-maynard.bsky.social lab @lieberinstitute.bsky.social - RNAscope at 3 levels of the habenula in human 🧠. 🟢 is MBP, 🟣 is GPR151 (lateral habenula), 🔴 is POU4F1 (general habenula), and 🟡 is TAC3 (medial habenula) 🔬🧪👩‍🔬

These understudied neuronal populations will be the topic of a panel at the upcoming @acnporg.bsky.social meeting, which I am co-chairing with @kr-maynard.bsky.social!

We are thrilled to announce that OneNeuro Co-Director Patricia Janak, Ph.D., has been elected as the 2026-2027 President of the Society for Neuroscience (SfN). @janaklab.bsky.social View the official announcement: www.sfn.org/publications...

We are very excited to welcome @drjennkim.bsky.social as the newest addition to the Translational Neuroscience Division @lieberinstitute.bsky.social where she will be working as a postodoc with @kr-maynard.bsky.social group.

Excited to share this huge team effort collaboration supervised by Stephanie Page in Translational Neuroscience @lieberinstitute.bsky.social and @stephaniehicks.bsky.social @jhubiostat.bsky.social to generate a spatio-molecular resource of the hippocampus in human 🧠 www.nature.com/articles/s41...

1/ I am beyond thrilled to share our new paper in @CellCellPress! We explored the regulatory principles underlying pleiotropy in psychiatric disorders. www.cell.com/cell/abstrac...

🚨 New paper published in @natmethods.nature.com! We introduce SpotSweeper, the first spatially-aware QC methods for spatial transcriptomics. 📰 Paper : nature.com/articles/s41... 💻 Code: github.com/MicTott/Spot... 📈 Website: mictott.github.io/SpotSweeper/ 🧵👇

Updated from the preprint, our paper, "Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation" is now published. www.cell.com/cell-reports...

Also, Bernie will be presenting this work on Wednesday night in the poster session #ACNP2024 W189 A Two-Resolution Spatial-Molecular Atlas of the Human Ventromedial and Arcuate Hypothalamus and Its Sex Differences