Thank you to all the organizers at the American Cancer Society Relay for Life event this weekend in Niagara Falls for all of their hard work on behalf of patients to help fund critical cancer research! @americancancersoc.bsky.social @roswellpark.bsky.social secure.acsevents.org/site/STR?pg=...

Scientific figures can strongly influence how research findings are interpreted. This ‘How to’ Comment article in Nature Human Behaviour outlines a practical strategy for creating figures that communicate clearly across audiences and scientific contexts. go.nature.com/3R00b1t #Academicsky 🧪

The May issue of Cancer Discovery @aacrjournals.bsky.social is online! The cover features work by @jeremynigri.bsky.social, Dave Tuveson, & colleagues showing myofibroblasts induce neuroplasticity to promote pancreatic inflammation & cancer progression. That & more: aacrjournals.org/cancerdiscov...

Distinct Tumor-Immune Ecologies in Patients with Lung Cancer Predict Progression and Define a Clinical Biomarker of Therapy Response

Nature research paper: The integrated stress response promotes immune evasion through lipocalin 2 go.nature.com/3MR7cQv

New FeiginLab paper is OUT! A commonly prescribed anti-anxiety drug reduces inflammatory signaling in pancreatic cancer through regulation of cancer-associated fibroblast activity! aacrjournals.org/cancerrescom...

Don’t miss our featured posters for Monday, April 20—highlighting even more critical discoveries from Roswell Park. See you at AACR! #AACR26

Repeated cloning cannot be sustained indefinitely in mammals, according to a 20-year study in mice published in Nature Communications. The results suggest that sexual reproduction is necessary to eliminate large-scale genetic mutations that can accumulate in mammalian clones. 🧬 🧪

WATCH: Emese Zsiros, MD, PhD, FACOG, of @roswellpark.bsky.social, discusses the @fda.gov approval of pembrolizumab plus paclitaxel with or without pembrolizumab for PD-L1–positive ovarian cancer. #gyncsm #oncology www.onclive.com/view/dr-zsir...

AI for cancer treatment information: Can academia stay in the game?

For readers interested in drug repurposing, this review summarizes the approaches, evaluates available in silico resources and presents case studies www.nature.com/articles/s41... rdcu.be/e60em

Thank you to the Sinclair Cancer Research Institute at Queens University for hosting my visit this week. It was fantastic to share our science from Roswell Park and to meet with so many investigators and trainees. @sinclaircri.bsky.social @queensuresearch.bsky.social @roswellpark.bsky.social

Review @natrevdrugdiscov.nature.com Therapeutic targeting of neuroimmune mechanisms in neurodegeneration www.nature.com/articles/s41...

Follow up to Doug Hanahan’s visionary article about the stages of cancer development from back in the 1990s www.cell.com/cell/fulltex...

Thank you to the American Cancer Society for highlighting our lab, this means a great deal. Please join the Making Strides Against Breast Cancer Fundraiser October 17, 2026 www.facebook.com/groups/makin...

In muscle-invasive bladder cancer, ctDNA-guided atezolizumab led to longer disease-free survival (9.9 vs. 4.8 months), as well as to longer overall survival (32.8 vs. 21.1 months), than placebo among ctDNA-positive patients. Full IMvigor011 phase 3 trial results and Research Summary: nej.md/3WIRtEg

🌅 Several studies have suggested checkpoint inhibitors dosed AM may be assoc w/ improved outcomes- but strong risk of confounding. Out now in #JCOOP: review of literature & discussion of how practices could actually implement this. Suspect will be very dependent on local AM traffic!

#Review 🕯️🕯️🕯️ The ability of #macrophages to eliminate cancer cells is controlled by phagocytic checkpoints. Veillette&Co discuss targeting these checkpoints for cancer therapy and outline strategies to address therapeutic efficacy concerns. 📖⬇️

Review: Linking tumour angiogenesis and tumour immunity

How can senescent cells, which are damaged and growth arrested, both block tumor initiation as well as fuel its growth? A recent study published in Cancer Discovery @aacrjournals.bsky.social from Lin Zhou in the lab uncovered some new insights into this puzzle. aacrjournals.org/cancerdiscov...

For readers interested in cancer therapies, this Review in the October issue discusses how metabolic modulators and dietary nutrients can improve the anticancer immune response and overcome drug resistance mechanisms rdcu.be/eLS8A www.nature.com/articles/s41...

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

Review: Targeting the peripheral neural-tumour microenvironment for cancer therapy

Endothelial-like cancer-associated fibroblasts facilitate pancreatic cancer metastasis via vasculogenic mimicry and paracrine signalling 🧪 #PancreaticCancer gut.bmj.com/content/74/9...

Happy to share our @bio-protocol.bsky.social describing an ex vivo method to measure CD8+ T-cell function. This was used in our recent papers in @emboreports.org (2025) and Molecular Cancer Therapeutics (2024). Thanks to Melissa Dolan for leading this effort - Congratulations to the whole team!

TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation @cp-cellrepmed.bsky.social @mklevings.bsky.social cell.com/cell-reports...

It’s out!!!!! We hope our review on aging, immunity, and cancer is helpful. Such a rewarding group effort led by Melissa Dolan, with Kendra Libby, Alison Ringle, and @vangalenlab.bsky.social So grateful to @gabriellebrewer.bsky.social @natrevcancer.nature.com for her efforts and support

The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. Learn more:

Editorial: Immune modulation and angiogenesis in regenerative and developmental processes.

How multispecific molecules are transforming pharmacotherapy www.nature.com/articles/s41... rdcu.be/ezbK0 This new article by Raymond Deshaies discusses how a wave of drugs designed to engage two or more entities are overcoming development barriers such as toxicity, rapid clearance and redundancy

Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors

Two common forms of cancer therapy can (in some cases) lead to further metastatic cancer themselves. What to do to fix that: