Open letter calling for the reinstatement of the National Science Board. This letter is from leaders of the National Academies Note: This does not refer to the leaders on paper such as presidents of the NAS, NAM, and NAE. www.standupforscience.net/nasem-letter... @standupforscience.net

I don't know who needs to hear this, but girl, if you are unhappy where you are, with who you became, you can change. You can start again. You need no man, no family support, just yourself. And remember, you’ll never feel ready because being ready isn’t a feeling, it’s a decision.

Breaking news: Indiana University plant microbiologist Roger Innes has been locked out of his laboratory by the school in response to a request by one of his federal funders. The move comes after Innes complained about the government’s prosecution of Chinese postdocs. https://scim.ag/4tsDqRr

#RIP Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor

Updates on the hantavirus situation from WHO (which we, beyond belief, are no longer part of). Seven suspected cases, three deaths. Case 1 boarded Apr 1, got sick Apr 6, died Apr 11. Likely Andes virus, given Argentina link. Consistent with infection before boarding. www.who.int/emergencies/...

Hello all, our lab is recruiting a PhD candidate to study how 3D genome folding impacts gene regulation in development. We're located at the Center for Integrative Genomics department of the University of Lausanne, Switzerland. Please email me if interested. #PhDPosition, #PhDOpportunity

The FDA approval of vepdegestrant for ESR1-mutant ER+/HER2− advanced breast cancer marks an important milestone for PROTACs! Beyond its importance for patients, this is a landmark validation of targeted protein degradation as a therapeutic modality 👏🏻 www.fda.gov/drugs/resour...

Bryn Nelson @seattlebryn.bsky.social This graph confirms what multiple cancer researchers told me: the NIH cut cancer research grants by 23% last year. And it had the $$ from Congress! The NIH simply failed to dole out many of the awards...

At the end of 2024, the National Academies put out a report concluding the NIH has woefully underfunded women’s health research, and they suggested $15 B should be invested over the next 5 years. Here’s what’s happened instead. Hard to study women’s health if you can’t say “women.” wapo.st/4euUt1c

Need a bit of advice from colleagues in Germany, especially MPI. I have a former student who moved to Germany from Russia for his Masters. We have a preprint, which was not yet published. MPI/his Uni made him sign a statement that he would not publish with Russian institutes 1/n

The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."

Just a reminder that 1yr ago today many dedicated NIH employees received RIF notices and started the process where many others were told they must leave their positions/ICs after years of service. The pain felt across the scientific community in the last year is also felt by those serving it.

Hollywood has gone too far this time.

Lab Leakers: "SARS-CoV-2 can't infect bats, so it must have been made in a lab". Science: "Let's do the experiment". SARS-CoV-2 behaves exactly like one would expect in a reservoir species - low-level infection, no overt disease, etc. Elegant study from Sato Lab: www.biorxiv.org/content/10.6...

Today's Official #NoKings 3 #Accessible & #Virtual Rally will include ASL interpretation, live captions, visual descriptions, & Spanish audio interpretation. Because resistance must be accessible, inclusive, & open to all & our rally will be for everyone, everywhere. Details: zurl.co/GHgs7

One of my favourite facts is that the spiky tail of a stegosaurus didn't used to have a specific name, until Gary Larson published this Far Side cartoon, at which point "thagomizer" was adopted by paleontologists.

This Nowruz, we set the table with tears for the many innocent lives lost. But we also hold onto to the message that no winter lasts forever. That spring will arrive, and the light returns. Wishing you peace from our lab !

Sad to hear that Pat Jacob has died aged 91. Pat was a seminal figure in the early days of human genetics. She co-discovered the 1st human chromosome abnormality - XXY Kleinfelter's syndrome in 1959, published contemporaneously with the discovery of trisomy 21 in Down’s syndrome by a French group.

In the last two weeks, 1% of new NSF awards were in biology. Just one grant of 97. One. Biology in the US is on hold until there’s a regime change.

Thank you for sharing this. We have a couple of students here who are going through not knowing if their families in Iran are ok. We keep checking on them but it is hard to know what comfort we can actually provide.

1/ Apply for an inter-disciplinary postdoc position in Heidelberg with the Health & Life Science Alliance Deadline: **31 March** Project proposals can be self-designed or adapt one of the outlines on the website ("List of project outlines for download") www.health-life-sciences.de/opportunitie...

We couldn’t agree more. Queen guitarist/astronomer Brian May and astrophysicist Derek Ward-Thompson talked with us about their new stereoscopic book of galaxies, that combines art and science to give people a 3D perspective of the universe. Listen to the full podcast episode now: buff.ly/LkdXS62

Apply now for the Signaling by Adhesion Receptors GRC June 7 - 12, 2026! The meeting has a terrific program that balances developmental biology, cell polarity, and adhesion and signaling. Please share! www.grc.org/signaling-by...

Nature Publishing Group finding more dastardly ways to lock us in, well beyond what I complained about in my letter declining reviewing for them

I'd like to see this problem analysed at the single cell multi-omics level 'Advances in research technolo- gies are crucial for the scientific enterprise but have an unintended consequence: when pow- erful techniques become widely available, they tend to be applied without a good question in mind.'

🌱 🚨Postdoc position – Plant Chromatin Biology (Strasbourg) Grob and Jullien Lab - details attached 📅 Apply by March 30, 2026 📩 [email protected] Please share with anyone who might be interested! #Postdoc #PlantScience #Epigenetics #Chromatin

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

🚨 New paper from our lab just published in Nature🚨 www.nature.com/articles/s41... Discover how 🌱 tumour formation is shaped by tissue context from the very beginning. Cancer is not driven by genetics alone ✨Fantastic team led by Greta Skrupskelyte, Eduardo Rojo, @hariajith.bsky.social

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD. www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

Afting, C., Walther, T., Drozdowski, O. M., Schlagheck, C., Schwarz, U. S., Wittbrodt, J., & Göpfrich, K. (2024). DNA microbeads for spatio-temporally controlled morphogen release within organoids. Nature Nanotechnology www.nature.com/articles/s41... #EpithelialMechanics

Look at this 🙂 #CryoEM Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org www.biorxiv.org/content/10.6...

How do compartmentalization & loop extrusion organize eukaryotic genomes beyond classical model organisms? Hi-C analysis of silkworm chromosomes by Drinnenberg, Muller, Mirny et al reveals new combination of these mechanisms, and a new, secluded “S” compartment link.springer.com/article/10.1...

If you are a student whose NSF GRFP application was returned without review for vague 'eligibility' reasons: 1) Let your department chair & Graduate School know. Encourage them to contact NSF & congress 2) Write to your congressional reps. 3) Write to [email protected] to request re-consideration;

Cool thread with examples of the role of cell junctions in collective cell migration! 🧪

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free

One of the best things I’ve read in a while:

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him. White. Hot. Rage.

FACETS Journal is looking for a Co-Editor-in-Chief to curate content, support diverse voices in research, and collaborate with our editorial team. Expertise in ecology, conservation biology, biodiversity, or environmental sciences is ideal. Learn more ▶️ https://ow.ly/Gbzv50Xo3Ks

Thank you so much for the great talk and wonderful science conversations! @takakulab.bsky.social and our students and other faculty really appreciated your sharing your science with us!

🥁 #FragileNucleosome is back on Jan 28! We are very excited to host @au-ho-yu.bsky.social and @gcloner.bsky.social as our first speakers of 2026! 📋Please don't forget to register for our 2026 seminar series: us06web.zoom.us/webinar/regi...

This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again. www.nature.com/immersive/d4...

⚠️ The final work of two former PhD students Till @tschwammle.bsky.social and Verena @verenamutzel.bsky.social is out! ➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...

Loved this from @simonmaechling.bsky.social - chemistry FTW… @dereklowe.bsky.social @carolynbertozzi.bskyverified.social

I wrote about this for Nature last July - good advice here from some award-winning academic mentors around the world: www.nature.com/articles/d41...

Some joy in this crazy world.

Janssen, V., & Huveneers, S. (2024). Cell–cell junctions in focus–imaging junctional architectures and dynamics at high resolution. Journal of Cell Science, #EpithelialMechanicsReview doi.org/10.1242/jcs....

Read the full story in our preprint! 👇 biorxiv.org/content/10.6... Excited to share this work with my co-first author Kevin Sabath - a fantastic collaboration between the @alex-stark.bsky.social and @plaschkalab.bsky.social labs! 🤝🧪