The Crunchometer is a low-cost, open-source technology that uses bite sound to democratize the microstructural analysis of feeding bouts on solid food: 🧪 The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure. doi.org/10.7554/eLif...

New essay in @currentbiology.bsky.social special brain-body issue! Fly lab meets psychiatrist: how bodily signals shape cognition and mental health. Great collaboration with Albino Oliveira-Maia showing @champalimaudf.bsky.social discovery ↔️ clinic at its best. www.cell.com/current-biol...

I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island. doi.org/10.1126/sci... With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others

www.nature.com/articles/s41... Emiliani Lab

All-optical experiments are great but @neurorussell.bsky.social found that opsin desensitization due to cross-talk between the imaging laser and the opsin causes major issues. These can be ameleorated with long inter-stimulus intervals & short imaging doses. All here: www.biorxiv.org/content/10.1...

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

they also don't have to be for fruit fly neurobiology to be interesting and worthy of study, so desperately trying to make flies = people is unnecessary and annoying.

🎇 Excited to finally share JL Romero Sosa’s publication! Results are from single-cell imaging in different subregions of rat frontal cortex during ✨de novo learning. Spoiler: everything is not everywhere all at once www.nature.com/articles/s41...

Congratulations to @betleylab.bsky.social and team on this beautiful study! www.nature.com/articles/s41...

Ever wonder if there are spatial maps in the brain outside the hippocampal-entorhinal regions? In this preprint, we describe a novel spatial map in the orbitofrontal cortex (OFC) that preserves the topological arrangements and distance between locations. However, ... www.biorxiv.org/cgi/content/...

Important and exciting work!

Even after recovery, relapse is heartbreakingly common in anorexia nervosa. Could the answer lie in the gut’s hidden signals? 🧵

The #FKNE Leadership Training Course for the Starting PI is open! Don't miss the opportunity to enhance your abilities and learn to tackle challenging moments as an early group leader! Application deadline: 15 Oct. 2025 fenskavlinetwork.org/fkne-leaders... @fens.org

What if many psychiatric disorders share the same hidden glitch in how the brain infers reality? In a new volume, Al Powers and I gather experts to examine how disrupted sensory inference across #vision, #touch, #proprioception and #interoception might unify our understanding.

Just published in World Psychiatry our study "Trauma under psychedelics: how psychoactive substances impact trauma processing" . Amazing work led by @ophirnetzer.bsky.social with the brave survivors of the Nova festival attack. Huge team effort, thx to all! 👉 doi.org/10.1002/wps....

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

❄️ Common shrews shrink their brains in winter. 🧠 The process is reversible and occurs because brain cells shrink, rather than die off. As a result, neuronal numbers stay constant and preserve brain function. I can defo relate to seasonal brain shrinkage. 🧪🦊🌍 Paper: www.cell.com/current-biol...

Nature research paper: Neural networks of the mouse visceromotor cortex go.nature.com/47N2hYP

I rarely dive into circuit-mapping papers, but this blockbuster from @ribeirocarlitos.bsky.social lab is a doozy! Check it out. www.biorxiv.org/content/10.1...

This is an exquisite demonstration of using intracranial recordings in humans to validate our findings that amygdala neurons encode the value of exploring in NHPs. www.nature.com/articles/s41...

Important insightful thread!

📅 Next week, we are excited to welcome Dr. @yoavlivneh.bsky.social from Weizmann Institute of Science. He will share his research on the #insular #cortex. 🥳 As always, everyone is welcome to join us at our Institute, and registration is not necessary! All info here: www.psych.mpg.de/events/40140...

Our brains use prediction in two seemingly contradictory ways. Our latest paper, just published in @natureneuro.bsky.social, investigates how we do it. 1/n www.nature.com/articles/s41...

Interpreting every comment as positive feedback

I am incredibly proud to share my first, first-author paper as a postdoc with @benhayden.bsky.social . How does the human hippocampus, known for encoding concepts, represent the meanings of words while listening to narrative speech? www.biorxiv.org/content/10.1...

www.nature.com/articles/s41... awesome new work out today! From the Lee lab in the intramural research program at NIMH!

Our paper @dulaclab.bsky.social on social homeostasis is online today! We characterized “social rebound” behavior after social isolation in multiple mouse strains and revealed its neural basis. Intriguingly, soft touch plays a key role in satisfying social need! www.nature.com/articles/s41...

In our new preprint, we show that microglia can prune astrocyte processes to regulate synaptic transmission and hypothalamic neuron activity. This work represents a huge team effort spanning ~10 years, and we are very excited to finally share it with the world!

🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

2024 marked the 10-year anniversary of the FENS-Kavli Network of Excellence. We warmly invite you to explore the 10-Year Report, showcasing its impact on science, mentoring, outreach, advocacy, and personal achievements. @fens.org @kavlifoundation.bsky.social fenskavlinetwork.org/fkne-10-year...

Check out these exciting findings! So happy that we could contribute to this fantastic story!

(1/11) Today I preprinted a lot of work from my postdoc with @dudman.bsky.social, which started with a question of how the nervous system balances flexibility with efficiency of learning. The thread below gives some background.... www.biorxiv.org/content/10.1...

To the tune 🎶 of Murder on the Dancefloor 🕺: Chaos in the Brickyard www.science.org/doi/10.1126/... - we're so busy making bricks, we forgot to assemble them into useful edifices, and now all the loose bricks are in the way!

Excited to share our new paper in Nature! 'Transcriptomic neuron types vary topographically in function and morphology' explores how neurons in the zebrafish optic tectum exhibit diverse functions and shapes despite similar transcriptional profiles. 🔗 rdcu.be/d9GVM

Great article by @kordinglab.bsky.social‬ on "why causal knowledge is pragmatically possible". The best arguments for causation--& only one we need--is pragmatic. Here pragmatic isn't weak/subjective, but connected to actual goals, utility & outcomes in the world. medium.com/@kording/why...

Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪

Innovative flavoring behavior in cockatoos! www.cell.com/current-biol...

How exercise during pregnancy can improve metabolic health of offspring: a key mediator (Serpina3c) from mother's white adipose tissue gets into fetal circulation, suppresses inflammation, as demonstrated in the mouse model www.nature.com/articles/s42... www.nature.com/articles/s42...

𝗜𝗻𝘀𝘂𝗹𝗮 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝗶𝗻𝘃𝗼𝗹𝘃𝗲𝗱 𝗶𝗻 𝗶𝗺𝗺𝘂𝗻𝗲 𝗵𝗼𝗺𝗲𝗼𝘀𝘁𝗮𝘀𝗶𝘀 The insula is the place of magic in the brain... (one of them at least) www.nature.com/articles/s41... (h/t @jrbneuropsiq.bsky.social ) #neuroskyence

New paper out in @currentbiology.bsky.social with the inestimable @kurtfraser.bsky.social and @janaklab.bsky.social. We think this work illuminates an important way the brain dynamically orchestrates motivation, and look forward to testing new hypotheses this inspires in disease models.

I’m thrilled to share our preprint presenting MORSE: a new way to simultaneously & quantitatively track patterns of neuromodulators/neuropeptides in vitro & in vivo using spatially multiplexed 3D imaging of 10+ green optical sensors on a microendoscope biorxiv.org/content/10.1101/2025.01.26.634931v1

Coming from an electrophys systems neuroscience background, it took me a long time to appreciate the importance of cell types in the brain. What's your favorite example where granular cell types (i.e. more than just E/I or subtypes of I cells) matter for systems neuro? Could be a fun substack post!

Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro Apply by: February 16th!

A gut bacterium behind sugar preference www.nature.com/articles/s41...

Excited to share this perspective with @yaelniv.bsky.social about how schemas might be learned and instantiated via reinforcement learning, latent cause inference, and dimensionality reduction, and what's the medial prefrontal cortex might be doing for all of these www.nature.com/articles/s41...

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social! academic.oup.com/endo/article... 🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

Beautiful work! Congrats Sonu, Meital and team!

An exciting approach to the "everything is everywhere(?)" discussion!