How do perceptual processes contribute to the development of psychiatric illness? @skhalsa.bsky.social and I have compiled this volume with experts from across the world to begin to answer this question.

What if many psychiatric disorders share the same hidden glitch in how the brain infers reality? In a new volume, Al Powers and I gather experts to examine how disrupted sensory inference across #vision, #touch, #proprioception and #interoception might unify our understanding.

Highly recommended reading for anyone interested in #interoception especially from a public-facing standpoint

This is an incredible tool for visualizing real-time activity of internal organ system dynamics in zebra fish - I trust it’s only a matter of time until we see a suite of “functional body connectivity” papers during various interoceptive perturbations… #interoception

🎉 Happy to share our latest paper on #Physiology&Behavior @elsevierconnect.bsky.social Together with Luigi Micillo, Nicola Cellini and Giovanna Mioni we explored the link between cardiac #interoception and time perception 🧵in the comments

Interesting molecular parallel to our human ISO findings: β-adrenergic and GABAergic modulation engage posterior insula, but using these states to guide action triggers zif268 plasticity in anterior insula. www.eneuro.org/content/12/8...

Public access to the first fly connectome that spans the whole CNS - BANC!: codex.flywire.ai?dataset=banc Different from prior connectomes - it is brain + cord (think spinal cord) We use it to ‘embody’ the system and find it resembles ‘subsumption architecture’ doi.org/10.1101/2025...

Postdoc job alert! I’m looking for someone with a PhD in neuroscience/psychology, psychiatry, biomed engineering, computational modeling or a related field to join my NIH-funded team at UCLA studying the neural & computational mechanisms of #interoception in anorexia nervosa 1/2

In the aftermath of last night’s west coast tsunami warning this article on emergency alerts rings true. Thankfully there does not appear to have been much damage theconversation.com/emergency-al...

Who needs podcasts when you have AI? Voila: the latest podcast on one of my papers, brought to you by NotebookLM! It’s not great (& gets a bit repetitive when you run several papers through it), but when you realize all they did was feed the paper into it, and generated a user-friendly output, whoa…

@peterkok.bsky.social and I wrote a book chapter on how layer specific fMRI can shine light on disorders hallmarked by perceptual disturbances. This is part of a series on Perceptual Dysregulation in Psychiatric Nosology edited by @skhalsa.bsky.social and Al Powers link.springer.com/chapter/10.1...

Latest article from our group articulating a harmonized vision for interoceptive neuroscience research, with my stellar co-authors who are also physician-scientists. It was a genuine privilege to work on this with them. More of this kind of empirical collaboration is needed!!

🚨 New paper out! Phase confusion: How inconsistent cardiac labeling obscures interoception research 🫀🧠 We unpack methodological incosistencies and propose a way forward with the HEARTS framework. In Biol. Psychol. - Open Access: 🔗 shorturl.at/YJhyn 1st paper of great @angeliacaparco.bsky.social!

What if 'gut feeling' was more than a metaphor, and the key to treating obesity and gastrointestinal disorders? This new commentary, born from the 2024 NIDDK workshop on Interoceptive Contributions to Obesity & DGBI is now out in Gastroenterology: sciencedirect.com/science/arti...

Can inflammation reveal why some individuals with depression can't feel joy? In this latest work led by Jonathan Savitz, Mike Irwin, and @mpwpaulus.bsky.social published in the American Journal of Psychiatry, we attempted to address just that: psychiatryonline.org/doi/10.1176/...

Thomas Ritz reviewing current progress in interoception research in light of Pennebaker's classic critiques, many of which still hold true

Huge congrats to @clairelavalley.bsky.social on this new paper. www.nature.com/articles/s41.... Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

In other news, the first human bladder transplant just took place at UCLA. Wild. One can't help but wonder about the impact on urinary #interoception... newsroom.ucla.edu/releases/wor...

This course is starting in T-minus 3 hours! We have a fantastic group of attendees and faculty speakers, and I’m really looking forward to the discussions with the group.

Nice paper showing a role for the HEP in antidepresssnt response to subcallosal DBS. Next question is, how does this affect cardiac and autonomic signaling? www.sciencedirect.com/science/arti...

Looks like Biological Psychology has switched over to 🦋

I’m super excited for the start of today’s first ever Keystone conference on #interoception. The speaker lineup is amazing and the Allen institute is breathtaking www.keystonesymposia.org/conferences/...

What a great tool for concretely visualizing NIH- and science-driven impacts. The contrast between conditions or processes is worth a look too: only 4 patents and 62 clinical trials on interoception vs 331 and 444 for anorexia nervosa. Be patient w/error responses - just refresh & try again.

We're hiring! The Shackman Lab is hiring a full-time postbac RA for the 2025-26 academic year. This is fabulous opportunity to learn, work, and play with us in the DMV before heading off to graduate school. shackmanlab.org/studycoordin...

Introducing a new tool from @tsbolt.bsky.social, find-viz (FMRI Interactive Navigation and Discovery Viewer)! It’s a browser-based visualization tool built with one purpose in mind: get researchers to spend more time looking at their fMRI data 🧠 @ohbmofficial.bsky.social @ohbmtrainees.bsky.social

Okay now maybe there is not so much time to attend this advanced course on #interoception, but with rolling admission, who knows? There’s a lot happening in this space these days, and attendees will be well equipped to reflect confidently on the recent progress!

Very excited to congratulate Ning Li and @clairelavalley.bsky.social on their new paper published in Molecular Psychiatry. "Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders" (nature.com/articles/s41...) 🧵👇

New paper alert! In this chapter, part of a volume led by the late Bud Craig’s colleagues Alan Simmons, Marc Wittmann, and Irina Strigo, we opine on the role of the insula in interoception and body image processing in anorexia nervosa and other health conditions. pubmed.ncbi.nlm.nih.gov/40178772/

Is interoceptive sensing unified across internal organs? 🫀🫁 Our high-powered psychophysical study (N=241) suggests not. Bayesian evidence indicates interoceptive processes are largely modality-specific—challenging the idea of a unitary interoceptive sense. 🔗 Read here: osf.io/preprints/ps...

Feeling overwhelmed by emergency alerts and nonstop breaking news? You’re not alone. In the wake of the LA wildfires & false emergency alerts my colleague Indu Subramanian and I explore how these notifications affect stress—and how to stay grounded amid the chaos: theconversation.com/emergency-al...

Pleased to be a part of this stellar team effort to consider the role of #interoception in Parkinson disease and imagine a framework for advancing progress in this area. Paul, it’s hard to believe it’s been that long, but let’s hope it continues to get better with age!

New paper alert—this is a master class on interdisciplinary collaboration updating the basic understanding and clinical outlook for neurocardiology. Led by Olu Ajijola Kalyanam Shivkumar and a cardiology dream team. #interoception physoc.onlinelibrary.wiley.com/doi/10.1113/...

If you’re attending the #ECNP meeting please consider stopping to see this, Charles is doing some amazing cutting edge work!

Can we enhance interoception by controlling the heart? Thrilled to share our new study, led by @ashleytyrer.bsky.social , where we use computational modeling to show that blockading peripheral noradrenaline uniquely alters awareness of heart rate & breathing! www.biorxiv.org/content/10.1... 🧵👇

Convergent and selective representations of pain, appetitive processes, aversive processes, and cognitive control in the insula www.biorxiv.org/content/10.1...

There’s still time to join us for this advanced course on #interoception in Venice. Individuals from all academic levels are welcome, and beyond interacting with others interested in this topic, there are ample opportunities to learn and explore!

There are now nearly 5000 papers on #interoception. And the output over the last 4 years is more than the previous 59. 🤯

📣 Come join us for the #MindBrainBody Symposium 2025! 📆 March 10-12, 2025 📍 Berlin & online 🔎 mindbrainbody.de Keynotes: - Ivan de Araujo - Nadine Gogolla - Maria Ribeiro @ribeironeuro.bsky.social - Markus Ullsperger - Tor Wager - Veronica Witte @veronicawitte.bsky.social #interoception

Another interoceptive physiology banger: "A top-down slow breathing circuit that alleviates negative affect in mice." www.nature.com/articles/s41...

Honored to coauthor this fMRI study on cardiac #interoception in FND. Disrupted insula, ACC activity during interoceptive attention underscores the neural basis of altered body-brain signaling in FND, bringing the field one step toward targeted interventions. pubmed.ncbi.nlm.nih.gov/39558709/

Want to learn more about #interoception and its role in the brain? Come join Sarah Garfinkel and me in Venice in May 2025 for the 2nd course on this topic. Beyond the sublime learning, terrific speaker lineup, amazing local attractions, and delicious Italian cuisine, we also have fun!

Thrilled to see this study officially published in eLife. Link here: elifesciences.org/articles/92820 and 🧵 below. Huge thanks to Dr. Emily Adamic, believe it or not, this study was a small part of her overall PhD thesis!

Link to videos for the recent NIH interoception investigator meeting: videocast.nih.gov/watch=52541

If you haven’t heard of Artificial Intelligence (AI) Large Language Models (LLMs) such as ChatGPT or Bard yet, this is a prime opportunity to learn about cutting edge beneficial applications—and risks—of this disruptive technology

Excited to co-chair tomorrow’s symposium on Artificial Intelligence Language Models and Psychiatry: Opportunities and Perils with Nick Obradovich at Technology in Psychiatry Summit #TIPS2023 featuring Olu Ajilore, Roy Perlis, Waqas Khan & Jina Suh, with the great Martin Paulus as discussant.

Just aired: “Body Electric" NPR podcast featuring a discussion with me on #interoception   www.npr.org/2023/10/31/1...

Hello interoception community, given the desultory mood elsewhere I thought I'd hop over here to be a part of this community as well. There are a lot of interesting things happening, not the least of which is this NIH interoception meeting on Nov 11th: www.nccih.nih.gov/news/events/... 🧠🫀 🧠🩺