Tal Laviv
@lavivtal.bsky.social
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Neuroscientists, microscopy, biosensors www.lavivlab.com
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in
@naturemethods.bsky.social
www.nature.com/articles/s41...
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Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain - Nature Methods
A first-in-class fluorescence lifetime-based FRET sensor for phosphatase and tensin homolog (PTEN) enables the dynamic monitoring of PTEN activity in cultured cells and in vivo with high spatiotempora...
https://www.nature.com/articles/s41592-025-02610-9
7 months ago
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Inna Slutsky
8 months ago
Yesterday, we held the 2024 Sieratzki Prizes Ceremony at the ISFN meeting in Eilat. We are so proud of our 2024 winners:
@yoavlivneh.bsky.social
, Arseny Finkelstein, David Omer,
@lavivtal.bsky.social
, and Inbal Ben-Ami Bartal!
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Eric Topol
9 months ago
How to improve memory and cognitive function in aged mice Fix the mitochondrial EC (excitation-coupling)
@science.org
representing a new potential path for replenishing neuronal energy reserves to counter brain aging
www.science.org/doi/10.1126/...
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Beautiful work by my the lab of Huan Ma, which I had the pleasure to contribute to. A fascinating link between neuronal activity, and transcription-excitation coupling in mitochodria to brain function and ageing
www.science.org/doi/10.1126/...
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Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice
Deciphering the complex interplay between neuronal activity and mitochondrial function is pivotal in understanding brain aging, a multifaceted process marked by declines in synaptic function and mitoc...
https://www.science.org/doi/10.1126/science.adp6547
9 months ago
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Hello there! My first try here: Sharing an in vivo image of a beautiful dendrite with a GFP knock-in to endogenous CaMKIIa
10 months ago
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Michael Ward
11 months ago
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
www.science.org/doi/10.1126/...
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Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...
https://www.science.org/doi/10.1126/science.adi5295
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Danielle Beckman
11 months ago
I'm very happy with how this image turned out and can't even wait for
#FluorescenceFriday
! I'm trying to detect Tau protein phosphorylation before forming full fibrillary tangles in
#Alzheimer
disease. Healthy neurons: (🟠NeuN), Dying neurons: pTau ( 🟣422), (🔵AT8). More info in the Alt tex! 🧠🔬
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