📺 Esta noche, a las 22:30 y en TPA (canal autonómico del Principado de Asturias), se estrena «Tamos Guapxs», un programa de divulgación científica en el que he tenido el grandísimo honor de participar en varios de sus episodios. Cada martes, un tema nuevo. ¡No os lo perdáis! 😃

✨Nueva edición de la «Noche Europea de los Investigadores e Investigadoras» de @uodivulga.bsky.social (@universidadoviedo.bsky.social) 🎲Estaremos en Gijón (18:00 - 22:00), donde podréis jugar a «La Oca Científica» del @iuopa.bsky.social y aprender sobre la investigación en cáncer. ¡Animaos! 😃

💪 We are back! 🥼 And it is our pleasure to welcome another student from the Bachelor's Degree in Biotechnology: Mariana Álvarez Cuetos, an undergraduate who is full of curiosity and enthusiasm. Welcome! 😃

And thus, the academic year ends. The most challenging and demanding one for me ever, perhaps, given the public examination (along with more than 200 teaching hours, grants, experiments, etc.). Fortunately, @ausisgroup.bsky.social keeps taking exciting small steps forward. See you in a few weeks!

And kudos to Alejandra Piedra Macías for her Master's Thesis, which has launched our search for autotic markers. She will now remain in AU·SIS, where she will continue this project during her PhD! 🥳 Congratulations to both of you! 😀

Once again, it is time to congratulate the students who have successfully completed their Bachelor's and Master's Theses with us! We applaud Miguel Rodríguez Monjardín, who was brave enough to conduct a conceptual study on autosis, proposing new hypotheses for his Bachelor’s Thesis. Well done! 👏

🥼 We continue to stay busy in July! This month, Pablo Jiménez, another student from the Bachelor's Degree in Biotechnology, has also joined our group. He is becoming familiar with our projects in preparation for working on his dissertation in the upcoming academic year. Welcome!

Aquí tenéis el divertido pero divulgativo #HiloTesis de @andres-autofagia.bsky.social, investigador predoctoral de nuestro grupo. ¡Bienvenidas/os al mundo de la autofagia! 🙂 (¡Gran trabajo, Andrés! 👏)

And for an update on autophagy and sleep, check out our review here: www.sciencedirect.com/science/arti... @charlotteboccara.bsky.social @arcticautophagy.bsky.social @cancelluio.bsky.social

www.sciencedirect.com/science/arti... Have a look at our views on the recent paper about fumarate and mitophagy.

🥼 In June we are joined by Paula (left), who is studying for a Bachelor's Degree in Medicine, and Víctor (right), pursuing a Bachelor's Degree in Biotechnology. They will be learning basic molecular biology techniques, and we truly appreciate their curiosity! Welcome! 🙂

📣 ¡Arranca #Pint25ES! 📰 Esta noche estaré en el Mala Noche, a las 19 h, para hablar del cáncer, y de cómo se informa sobre él en los medios de comunicación. ¿Son ciertos los titulares que nos llegan? ¡Nos vemos! #Pint25OVD

¡Gracias a todas las personas que os habéis pasado por la Feria! 🔵🟡 Especialmente a las/os peques que se acercaron a jugar y aprender en nuestro espacio. 😃

📣 ¡Nueva edición de la Feria de la Ciencia y la Innovación de Asturias! 🧬 Ahí estaremos, por tercer año, para acercar a la gente el mundo de la biología molecular del cáncer y de la investigación. De 10:00 a 14:30 (estudiantes) y de 16:30 en adelante (público general). 🔵🟡

The first milestone of our collaboration with Dr. Vega-Rubín-de-Celis's lab has been completed! Time has flown by, as Dr. Larafa finished her stay with us last week. She has now returned to Germany, along with our own María, to continue our collaboration there. Great initial steps! 🙂

Fun fact: alternative options, such as "trinity", "triplet" and "trio", were also considered at some point. 😅

Our PKA-autophagy story by outstanding graduate student Ashley Segura (co-led with Rose Citron) published in @embojournal.org, dissects a deep connection between autophagy and PKA in neuronal signaling, with implications for neurological disease. Great collaboration with @manciaslab.bsky.social!

The Lab Coat Rack 🥼

Happy to announce a new paper on a very promising monomeric red fluorescent protein (mScarlet3-H) from the Wu, Zheng, Piatkevich, and Fu labs. mScarlet3-H is bright, photostable, and physically stable, making it versatile for advanced bioimaging. www.nature.com/articles/s41...

Hace 25  años que el IUOPA abrió una ventana a la formación de nuevos investigadores. Desde aquel curso 2000 hasta ahora, más de 400 estudiantes han pasado por el Doctorado o el Máster en Biomedicina y Oncología Molecular de la Universidad de Oviedo.

I am extremely pleased to share our latest work on the efficacy of the NDP52GE variant in combating the accumulation of pathological forms of Tau and which is emerging as a protective factor against #AlzheimerDisease. #autophagy rdcu.be/ehPVj Kudos to Anna who drove this project! « Ad maiora ... »

Job ad is here! Check it out :)

C'mon guys, don't notify grant rejections on Friday afternoon!

Check out our latest Comment in Nature Cell Biology on #autophagy (the mechanism that cells of your body use to recycle damaged material and slow ageing). While declining autophagy is often seen as a hallmark of #ageing, we explore emerging exceptions to this idea. www.nature.com/articles/s41...

My postdoctoral work on the non-canonical role of an autophagy-related protein at the spindle pole body (SPB) is now out in @plosbiology.org (doi.org/10.1371/jour...).

🧵 Oferta de trabajo en el @IUOPA: 📌 Postdoctoral senior para el Instituto Universitario de Oncología de Asturias. 🗓️ Fecha límite de presentación de solicitudes: 1 de mayo de 2025 📍 Ubicación: Área de #Microbiología, Facultad de Medicina, Universidad de Oviedo. Más info👉

I’ve always liked Tom Pollard’s framing of biological research: genetics gives you the parts list, biochemistry the functions/reactions and rates, cell biology the localisations and dynamics, and structural biology the fine detail. Put it all together and you get a mechanistic picture. 🤩

🚨 PhD Opportunity @INRAE/NUMEA lab 🚨 Passionate about cellular stress responses? Join the Seiliez team to investigate how chaperone-mediated autophagy (CMA) helps fish combat hypoxic stress 🐟 🐠 🐡 Please help spread the word 😉 More details here 👉 jobs.inrae.fr/en/ot-25516

🚀Our latest work reveals how RAB5c orchestrates LC3-associated phagocytosis (LAP) to boost macrophage defense against A. fumigatus! 🦠🔬 🧵 Dive into the mechanisms linking endosomal traffic to innate immunity! #Immunology #Autophagy #Phagocytosis #Macrophage #Preprint doi.org/10.1101/2025...

Walking speed vs. Professors

And the figure everyone wants to see - more new posts on new science now happening on bsky.

THREAD The numbers are in. @bsky.app research sharing volumes vs X Formerly Twitter In March 2024, on most days, Bluesky hosts more posts linked to research published in 2025 than X. By quite a lot. Release the Kraken... #AcademicSky #HigherEd #Altmetrics 1/11

Happy to see our invited review on "Advances in mitophagy initiation mechanisms" is now online! We summarised the recent important discoveries in understanding how our cells trigger the formation of "cellular garbage bags" to clean up their unwanted mitochondria. doi.org/10.1016/j.ce...

New preprint drop! Check out work from @jimmy-ly.bsky.social et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. "Blue-tutorial" thread below. www.biorxiv.org/content/10.1...

Submit your abstracts/scholarship applications by 3/27 (11:59pm MST) to present at the Autophagosomes and Endolysosomes meeting. Join Christina Towers & other leading experts! Dive in: keysym.us/KSAutophagy25. #KSAutophagy25 #autophagosome #endolysosomes youtu.be/zTfeKZSGF9Y @bealelab.bsky.social

Happy to share the latest work from the lab @crick.ac.uk. Outstanding work from Di Chen and Tony Fearns showing the link between Mtb membrane damage, calcium leakage and ATG8/LC3 lipidation in macrophages. Congratulations Di and Tony! www.science.org/doi/10.1126/...

I am looking for a post/doc! Are you motivated to study the fundamental questions in autophagy? Have a look!

A few favorite images:

In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment https://www.biorxiv.org/content/10.1101/2025.03.24.645001v1

New preprint alert! In this study, we show that ATG2A engages Rab1 membranes, which are essential to autophagy. These membranes are recruited to the PAS at an early stage during autophagosome biogenesis. Tutorial to come! www.biorxiv.org/content/10.1...

🚨 Call for Submissions! 🚨 We're thrilled to announce the opening of the Beth Levine PhD Prize! 🎓🏆 If you’ve completed an outstanding thesis in #Autophagy, this is your chance to get recognized. 📅 Deadline: May 19th, 2025 🔗 Apply now: cfatg.org/bourses/prix...

Research suggests that contrary to scientists' worries, there is no reputational penalty for shared first authorships, even for the person named second ― at least under experimental conditions1. https://go.nature.com/4c46IPm

Green card holders detained. A French researcher denied entry for anti-Trump messages. A new travel ban on 40+ countries coming. Given all these encroachments on travelers' civil liberties, we've updated our guide to digital privacy while crossing US borders. www.wired.com/2017/02/guid...

Super excited to share our latest work on deciphering the #Ubiquitin Code “𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀” @cp-molcell.bsky.social 1/8 www.cell.com/molecular-ce...

Excited that this is finally out! Great work by Jared Field for his PhD. @chrimanitoba.bsky.social @dream-diabetes.bsky.social www.tandfonline.com/doi/full/10....

Important feature on animal models and alternatives in @nature.com www.nature.com/articles/d41...

We just opened the @cfatg.bsky.social starter pack! If you are new on Bluesky and want to follow the labs/scientists affiliated to CFATG, join us !! go.bsky.app/JGcpKbB

🚨 Final Reminder – 1 Week Left to Apply! 🚨 Time is running out! ⏳ There’s only one week left until the application deadline for the MENTOR PhD Program. 📅 Deadline: March 28, 2025 🔬 Fully funded PhD positions in cutting-edge research 🌍 International secondments & top-tier training

We published an update of our excellence mapping at www.excellencemapping.net

In-cell architecture of the mitochondrial respiratory chain | Science www.science.org/doi/10.1126/...