Louis-Marie Bobay
@lbobay.bsky.social
π€ 229
π₯ 227
π 8
Associate Professor. NC State. Microbial Genomics, Evolution, Bioinformatics.
reposted by
Louis-Marie Bobay
Olivier Borkowski
about 15 hours ago
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
doi.org/10.64898/202...
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Louis-Marie Bobay
Eduardo Rocha
3 days ago
The distinction between virulent & temperate phages gets fuzzier if one can find so many virulent phages in the sequences of bacterial genomes coming from standard lab "pure" cultures. Check Peter's thread on our work and the N&V by Carson & Hynes:
doi.org/10.1038/s415...
#phagesky
#microsky
add a skeleton here at some point
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Nandita Garud
22 days ago
If you are interested in this work and are looking for a postdoc position, please get in touch -- we are actively looking for someone to join our group at UCLA!
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Louis-Marie Bobay
Waggoner Lab
22 days ago
Recombination between strains fuels pervasive adaptive evolution among human gut commensal bacteria, and strongly implicate host diet and lifestyle as critical selection pressures
@nature.com
@nanditagarud.bsky.social
www.nature.com/articles/s41...
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Louis-Marie Bobay
Julie Meyer, PhD
26 days ago
Looking for a postdoc in 2026? The Ewel fellowship at UF provides $70K salary and $20K research support for 2 yrs. I'm happy to sponsor a postdoc interested in microbial ecology of Florida coastal ecosystems (seagrass, coral, mangroves, springs). π¦ Due 1/11/26
postdoc.aa.ufl.edu/current-post..
.
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https://postdoc.aa.ufl.edu/current-post..
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Louis-Marie Bobay
Manuel Kleiner
27 days ago
We are recruiting a Lab Manager/Research Specialist
jobs.ncsu.edu/postings/225...
Please re-post, thank you
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Research and Lab Specialist
The Kleiner Lab at North Carolina State University (www.kleinerlab.org) is seeking a Research Specialist to support ongoing research on complex microbial communities, microbial symbioses, and metaprot...
https://jobs.ncsu.edu/postings/225502
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Louis-Marie Bobay
Heather Hendrickson
29 days ago
Itβs officially happening folks! The Microbial Population Biology Gordon Research Conference is back in Andover, New Hampshire starting June 27th of 2027! See you there!!
@wcratcliff.bsky.social
@ksbakes.bsky.social
@surtlab.bsky.social
#microsky
#mevosky
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Susan Johnston
about 1 month ago
Are you a recombination researcher heading to
#SMBE2026
? Submit your abstract to our Symposium, organised by Marie Raynaud, Laurent Duret, and myself. We're excited to have Aurora Ruiz-Herrera from UAB Barcelona as our invited speaker. π§¬π¦π¦ πΏππππͺ±
@aruizherrera.bsky.social
@duret-lbbe.bsky.social
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Louis-Marie Bobay
Institut Pasteur | 130 years of biomedical research
about 1 month ago
π¬ Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies π Deadline: Feb 9, 2026 π₯ 2-12 years post-PhD Apply now π
research.pasteur.fr/en/call/crea...
#JobOpportunity
#Research
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Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
https://research.pasteur.fr/en/call/creation-of-new-junior-research-groups-at-the-institut-pasteur-call-for-applications-2026/
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sylvain Brisse
about 1 month ago
Opening of a Group Leader position in AI in genomics at Institut Pasteur
@pasteur.fr
, Paris
research.pasteur.fr/en/call/mid-...
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Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research
Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...
https://research.pasteur.fr/en/call/mid-career-group-leader-position-in-ai-in-genomics-at-institut-pasteur-paris/
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Louis-Marie Bobay
Javier del Campo
about 1 month ago
Natural and artificial variations of the standard genetic code
www.cell.com/current-biol...
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Louis-Marie Bobay
PLOS Biology
about 1 month ago
How do root
#microbes
respond to drought? This study finds that
#Streptomyces
responses are strain-specific & functionally diverse, with traits &
#plant
effects varying independently of phylogeny, stressing the need to resolve functional traits at the strain level
@plosbiology.org
π§ͺ
plos.io/4owtjIT
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Louis-Marie Bobay
Arkadiy Garber
about 1 month ago
metaTraits: a large-scale integration of microbial phenotypic trait information
academic.oup.com/nar/advance-...
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metaTraits: a large-scale integration of microbial phenotypic trait information
Abstract. Microbes differ greatly in their organismal structure, physiology, and environmental adaptation, yet information about these phenotypic traits is
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf1241/8343513
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Louis-Marie Bobay
Monica H Green
about 1 month ago
Another addition to the 2nd Plague Pandemic bibliography. Why, when this relates to the 3rd Pandemic, instead of the 2nd? B/c the science about plague we've acquired from the unfortunate experience of Madagascar informs everything we can do in
#medhist
.
www.nature.com/articles/s42...
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Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar - Communications Biology
A comprehensive phylogenetic analysis of Yersinia pestis, the causative agent of plague, provides insight into the diversity and evolution of this pathogen in Madagascar. This study provides valuable ...
https://www.nature.com/articles/s42003-025-09109-1
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Louis-Marie Bobay
Aude Bernheim
about 1 month ago
π§¬π‘οΈHow are new immune mechanisms created? We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in
@pnas.org
. π
@matthieu-haudiquet.bsky.social
, Arpita Chakravarti & all authors!
doi.org/10.1073/pnas...
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Rob Edwards
about 1 month ago
Long read Metagenomics,
#phage
and
#prophage
in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years
#phagesky
www.nature.com/articles/s41...
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Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phageβ...
https://www.nature.com/articles/s41586-025-09786-2
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Simon Roux
about 2 months ago
Some fantastic sessions being planned for ASM Microbe 2026, including "Long-term Dynamics of Environmental Microbiomes", and "Eco-evolutionary Dynamics of Phages and Their Roles in Horizontal Gene Transfer". Get your abstract(s) ready, and join us June 4β7, 2026 in D.C. !
asm.org/events/asm-m...
add a skeleton here at some point
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Louis-Marie Bobay
Ran Blekhman
about 2 months ago
Due to the shutdown, NIH cancelled >370 study sections, impacting >24,000 applications Rescheduled meetings will only discuss 30-35% of applications, have simplified summary statements (no narrative paragraph), and a new category - "competitive but not discussed"
grants.nih.gov/grants/guide...
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NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-26-012.html
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Louis-Marie Bobay
PLOS Biology
about 2 months ago
The ecological roles of bacterial
#immune
systems are poorly understood. Rafael Custodio
@ellinoralseth.bsky.social
@brockhurstlab.bsky.social
@brownlab.bsky.social
& Edze Westra explore how mobile genetic elements and bacterial defenses shape
#microbiome
structure and function π§ͺ
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Bacterial immune systems as causes and consequences of microbiome structure
Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile geneticβ¦
https://plos.io/49tAvSf
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Louis-Marie Bobay
Stephen Turner
over 1 year ago
Review: Inference and applications of ancestral recombination graphs
https://www.nature.com/articles/s41576-024-00772-4
(read free:
https://rdcu.be/dVyQH
) π§¬π₯οΈ
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Louis-Marie Bobay
Mike Barker
3 months ago
I'm recruiting PhD students for the Barker Lab
@uofa-eeb.bsky.social
We study plant evolutionary genomics - polyploidy, hybridization & machine learning for genome evolution. Work with Selaginella, Xanthisma, Brassica & more. Funding available via CAMBIUM Fellowships. Reach out if interested! π§¬π΅π€
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Louis-Marie Bobay
Michael Baym
about 2 months ago
Hot off the press! Our latest paper led by
@fernpizza.bsky.social
, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
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Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
https://www.science.org/doi/10.1126/science.adx0665
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Didier Mazel
about 2 months ago
Phenomenal! WOOOOOOOW .... speechless
www.nature.com/articles/s41...
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Semantic design of functional de novo genes from a genomic language model - Nature
By learning a semantics of gene function based on genomic context, the genomic language model Evo autocompletes DNA prompts to generate novel genes encoding protein and RNA molecules with defined acti...
https://www.nature.com/articles/s41586-025-09749-7
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Louis-Marie Bobay
Daan Speth
about 2 months ago
Our paper describing the GlobDB is now published in
@bioinfoadv.bsky.social
doi.org/10.1093/bioa...
The GlobDB is the largest species dereplicated genome database currently available, containing 306,260 species representatives. More information on
globdb.org
1/5 π₯οΈπ§¬π¦
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GlobDB: a comprehensive species-dereplicated microbial genome resource
AbstractMotivation. Over the past years, substantial numbers of microbial speciesβ genomes have been deposited outside of conventional INSDC databases.Resu
https://doi.org/10.1093/bioadv/vbaf280
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Ellinor Alseth
about 2 months ago
Very happy to see this piece out in
@plosbiology.org
, on the bacterial immune systems and microbial communities. It was a great team effort with Rafael Custodio,
@brockhurstlab.bsky.social
,
@brownlab.bsky.social
, and Edze Westra! π¦ π§«
#phagesky
#mevosky
journals.plos.org/plosbiology/...
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Bacterial immune systems as causes and consequences of microbiome structure
Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic ele...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003489
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Our latest paper is out with
@adiop.bsky.social
and
@gmdouglas.bsky.social
. We analyzed the extent of homologous recombination between bacterial species (introgression) and how it affects species borders (it can vary a lot depending on the approach used to classify species!).
rdcu.be/eQAMf
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Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy
Nature Communications - It is commonly thought that bacterial species borders tend to be fuzzy, due to frequent exchange of DNA. Here, Diop et al. quantify the patterns of gene flow between core...
https://rdcu.be/eQAMf
about 2 months ago
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Kevin Debatisse
about 2 months ago
Mechanistically, incoming ssDNA is a game changer: it promotes attC site folding, triggers integrase expression via SOS, and allows cassette excision without the need for replicative resolution. This suggests both intra- and inter-bacterial shuffling shape integron recombination dynamics. 4/5
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reposted by
Louis-Marie Bobay
Cameron Thrash
about 2 months ago
Omnipresent Allies: The Role of Temperate Phages in Microbial Adaptation Across Ecosystems
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
#jcampubs
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Omnipresent Allies: The Role of Temperate Phages in Microbial Adaptation Across Ecosystems
This review synthesises evidence from culture-dependent systems and complex environments, concluding that temperate phages drive microbial adaptation across individual, population and community level...
https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.70204?af=R
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Louis-Marie Bobay
Paula Ramiro-MartΓnez
6 months ago
We discovered a universal scaling law linking copy number and plasmid size, which can be used to predict the PCN of your favorite plasmid! 6/7
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Louis-Marie Bobay
Cameron Thrash
about 2 months ago
Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy
www.nature.com/articles/s41...
#jcampubs
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Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy - Nature Communications
It is commonly thought that bacterial species borders tend to be fuzzy, due to frequent exchange of DNA. Here, Diop et al. quantify the patterns of gene flow between core genomes across 50 major bacte...
https://www.nature.com/articles/s41467-025-64947-1
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Louis-Marie Bobay
Ben Good
about 2 months ago
Excited to share some new work led by grad student Sophie Walton (w/
@petrovadmitri.bsky.social
). We used in vitro gut communities to study how natural selection acts on strains of the same species as they compete within larger communities. Check out Sophie's thread below for details!
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Fidy Rasambainarivo
2 months ago
The Department of Biology at
@eastcarolinauniv.bsky.social
seeks to fill a tenure-track faculty at the Assistant Professor level with expertise in evolutionary Biology! Come join us!
ecu.peopleadmin.com/postings/89839
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Assistant Professor
The Department of Biology at East Carolina University (http://www.ecu.edu) seeks to fill a tenure-track faculty position (9-month appointment) at the Assistant Professor rank with expertise in evoluti...
https://ecu.peopleadmin.com/postings/89839
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After defunding science, he is now attacking the colleges and departments of Interior Design
add a skeleton here at some point
2 months ago
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Soil Microbial Ecology Group
3 months ago
π£ PhD Scholarship Opportunity for International Students! Are you looking to do a PhD in soil microbial and viral ecology? βοΈ Get in touch now!! β Requirements: Masters degree, Distinguished CV, Highly motivated β³ Application deadline: November 24
www.univ-lyon1.fr/recherche/fo...
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APPEL A PROJET
https://www.univ-lyon1.fr/recherche/formation-doctorale/appel-a-projet-bourse-eiffel-2026
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Parul Johri
2 months ago
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
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Ben J Woodcroft
3 months ago
In the meantime, we've been collecting a list of these at
tinyurl.com/mag-collecti...
. Feel free to add more you find. See also GlobDB from
@daanspeth.bsky.social
which incorporates some of these into a new MAG collection
arxiv.org/abs/2506.11896
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Public MAG datasets not available at NCBI or ENA
Some metagenome assembled genome (MAG) datasets are not available in the standard locations (NCBI / ENA / etc) for a variety of reasons. Here you can contribute new ones you come across. To be recorde...
http://tinyurl.com/mag-collections
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Louis-Marie Bobay
Carolyn Ibberson
3 months ago
Come join us in Knoxville! The Dept. of Microbiology π§«π¦ at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.). Microbial Drivers of Chronic Disease:
apply.interfolio.com/173153Quantitative
Microbe-Plant-Environment Interactions:
apply.interfolio.com/173345
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Dmitri Petrov
3 months ago
For population genetics and evolutionary biology folks in the Bay Area: the next BAPG will be hosted by Stanford CEHG and the Petrov lab at Stanford on 12/6. Registration is free but required. The deadline for talk submission is Nov. 16. Hope to see you soon! Pls RT!
docs.google.com/forms/d/e/1F...
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https://docs.google.com/forms/d/e/1FAIpQLScswsjHaX0Rr12iDXznWc06c8Ck3BJoXQLI5vOLR2HLsURSOg/viewform
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David Enard
3 months ago
Come join us in beautiful Britanny, France in May 2026 for a workshop that I am organizing with
@lucievirevolte.bsky.social
and
@psudmant.bsky.social
on Rapid host adaptations to infections:
sites.google.com/berkeley.edu...
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Louis-Marie Bobay
Simon Roux
3 months ago
Now published: EnVhogDB, a large database of viral protein family HMM profiles to help functional annotation of new phage genomes -
peercommunityjournal.org/articles/10....
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EnVhogDB: an extended view of the viral protein families on Earth through a vast collection of HMM profiles
https://peercommunityjournal.org/articles/10.24072/pcjournal.627/
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Louis-Marie Bobay
Christina Burch
3 months ago
#microsky
#mevosky
The UNC Chapel Hill Biology Department is hiring 2 Teaching Assistant/Associate Professors with expertise from any area of biology. Individuals with expertise in microbiology are particularly encouraged to apply. Read more and apply at
unc.peopleadmin.com/postings/307...
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Two (2) Open Rank Teaching Faculty
The Department of Biology at the University of North Carolina at Chapel Hill seeks applicants for two (2) Teaching Faculty positions to be effective July 1, 2026. These positions will be fixed-term 9-...
https://unc.peopleadmin.com/postings/307445
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Louis-Marie Bobay
Leslie Rissler
3 months ago
NSFβs doors will be closed at 1:30 pm today. While you may be able to submit things, there will be no staff to process anything. In fact it is illegal for us to even open our work computers or email during a shutdown. A very few rotators may be able to communicate, so check out of office responses.
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Navigating A Government Shutdown: One-Stop Resource Page
As of 12:01 AM on October 1, Donald Trump and Republicans in Congress have shut down the government.
https://raskin.house.gov/2025/10/navigating-a-government-shutdown-one-stop-resource-page
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Louis-Marie Bobay
Megan Behringer
3 months ago
Our lab is hiring!! We are looking for a research assistant who will be involved with our experimental evolution studies on how stress affects population dynamics in E. coli. Great opportunity for recent grads! E-mail for more info and apply here:
ecsr.fa.us2.oraclecloud.com/hcmUI/Candid...
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Louis-Marie Bobay
Seema Sheth
3 months ago
Tenure-track Assistant Professor position in Bioinformatics in the Department of Biology at the University of San Francisco
usfca.wd5.myworkdayjobs.com/en-US/USF_Fu...
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Assistant Professor, Tenure-Track, Department of Biology, University of San Francisco
Job Title: Assistant Professor, Tenure-Track, Department of Biology, University of San Francisco Job Summary: The Department of Biology at the University of San Francisco invites applications for a fu...
https://usfca.wd5.myworkdayjobs.com/en-US/USF_Full-Time_Faculty/job/USF-Hilltop-Campus/Assistant-Professor--Tenure-Track--Department-of-Biology--University-of-San-Francisco_R0011691
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Lecuit Lab
4 months ago
We are hiring a postdoc in bacterial genomics and evolution.
research.pasteur.fr/wp-content/u...
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https://research.pasteur.fr/wp-content/uploads/2024/09/research_pasteur-funded-postdoctoral-position-in-the-lecuit-lab-at-institut-pasteur-postdoc.biu2025.pdf
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Louis-Marie Bobay
Benjamin Wolfe
4 months ago
Such a delight to share our work on the evolution of a cheese rind fungus in
@currentbiology.bsky.social
. This is the fantastic PhD work of
@nicolasleonlouw.bsky.social
and resulted from amazing collaborations, a wedding proposal(!), an undergrad course, & more! π§΅
www.cell.com/current-biol...
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Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation
Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...
https://www.cell.com/current-biology/fulltext/S0960-9822%2825%2901119-4
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Eduardo Rocha
4 months ago
Willing to join us
@pasteur.fr
for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check
www.pasteur.fr/en/education...
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Eduardo Rocha
4 months ago
Very happy to see this one out:
doi.org/10.1093/molbev/msaf192
Here, we assessed the contribution of natural transformation to the acquisition of novel genes. See preprint thread.
@molbioevol.bsky.social
#microsky
#evobio
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Molecular Biology and Evolution
5 months ago
@swstkm.bsky.social
&
@martinlercher.bsky.social
evaluate HGT inference methods, showing that those analyzing gene family presence/absence patterns across species trees outperform approaches based on gene tree-species tree reconciliation. π
doi.org/10.1093/molbev/msaf166
#evobio
#molbio
#HGT
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Horizontal Gene Transfer Inference: Gene PresenceβAbsence Outperforms Gene Trees
Abstract. Horizontal gene transfer is a fundamental driver of prokaryotic evolution, facilitating the acquisition of novel traits and adaptation to new env
https://doi.org/10.1093/molbev/msaf166
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Eduardo Rocha
5 months ago
Great to see this out. The impact of antibiotics on the gut phages and what it tells us of the disruption associated with antibiotics .
www.cell.com/cell-reports...
Check
@eugenpfeifer.bsky.social
thread
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