Lecuit Lab
@biupasteur.bsky.social
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Biology on Infection Unit at Institut Pasteur and Inserm
We are hiring a postdoc in bacterial genomics and evolution.
research.pasteur.fr/wp-content/u...
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https://research.pasteur.fr/wp-content/uploads/2024/09/research_pasteur-funded-postdoctoral-position-in-the-lecuit-lab-at-institut-pasteur-postdoc.biu2025.pdf
9 days ago
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reposted by
Lecuit Lab
Institut Pasteur | 130 years of biomedical research
3 months ago
🏆 Congratulations to Simonetta Gribaldo
@sgribaldo.bsky.social
and Marc Lecuit
@biupasteur.bsky.social
! Our two researchers have been awarded prestigious ANR Chairs of Excellence in Biology/Health for their innovative projects.
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"Chairs of Excellence in Biology/Health": two new Institut Pasteur laureates
The Institut Pasteur is delighted that two of the winners of the new "Chairs of Excellence in Biology/Health" call for proposals round launched by the French National Research Agency (ANR) are its own...
https://www.pasteur.fr/en/research-journal/news/chairs-excellence-biologyhealth-two-new-institut-pasteur-laureates
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Lecuit Lab
Nature Reviews Microbiology
5 months ago
New online! Chikungunya virus and other emerging arthritogenic alphaviruses
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Chikungunya virus and other emerging arthritogenic alphaviruses
Nature Reviews Microbiology, Published online: 07 May 2025; doi:10.1038/s41579-025-01177-8In this Review, Weaver and colleagues discuss the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology, transmission dynamics, evolution, pathophysiology and immune responses. They also outline strategies and countermeasures to anticipate and mitigate the impact of arthritogenic alphaviruses on human health.
https://www.nature.com/articles/s41579-025-01177-8?utm_source=bluesky&utm_medium=social&utm_campaign=nrmicro
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Lecuit Lab
Thelonevirologist
5 months ago
Chikungunya virus and other emerging arthritogenic alphaviruses
www.nature.com/articles/s41...
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Chikungunya virus and other emerging arthritogenic alphaviruses - Nature Reviews Microbiology
In this Review, Weaver and colleagues discuss the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology, transmission dynamics, evolution, pathophysiology and immune responses...
https://www.nature.com/articles/s41579-025-01177-8
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We are hiring! Interested in infection biology, immunology, microbiology? Funded postdoctoral position in our lab at Institut Pasteur
research.pasteur.fr/en/team/biol...
@inserm.fr
Contact us at
[email protected]
research.pasteur.fr/en/job/funde...
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Funded postdoctoral position in the Lecuit lab at Institut Pasteur - Research
https://research.pasteur.fr/en/job/funded-postdoctoral-position-in-the-lecuit-lab-at-institut-pasteur/
7 months ago
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Lecuit Lab
Louis-Jeantet Foundation
10 months ago
📢NOMINATIONS for the 2026
#LouisJeantetPrize
and
#CollenJeantetPrize
are open. Support great
#EuropeanResearch
and submit your nomination by February 21, 2025. 🙏Please share!
jeantet.ch/en/nominatio...
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Nominations | Fondation Louis-Jeantet |
https://jeantet.ch/en/nominations/
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6/6 Thanks to everybody involved, including Enzo Gadin, Arthur Frouin, Olivier Disson, Lei Huang, Charlotte Gaultier, Afonso Vieira,
@clairemaudet.bsky.social
,
@epcrocha.bsky.social
, Hugues Aschard,
@pasteur.fr
,
@inserm.bsky.social
10 months ago
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1/6 Excited to share our new findings published today in
@naturemicrobiol.bsky.social
, explaining what drives virulence heterogeneity in Listeria monocytogenes!
@lukashafner.bsky.social
@biupasteur.bsky.social
www.nature.com/articles/s41...
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Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes - Nature Microbiology
Differences in virulence across the Listeria monocytogenes species are determined by the fine-tuning of SigB pathway responsiveness and reflect host adaptation.
https://www.nature.com/articles/s41564-024-01859-8
10 months ago
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2/6 Previously, bacterial virulence was thought to reflect the content of core virulence genes as well as the presence of accessory virulence genes, which account for virulence heterogeneity.
www.youtube.com/watch?v=liJm...
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Differential stress responsiveness determines virulence heterogeneity in Listeria monocytogenes
YouTube video by Lukas Hafner
https://www.youtube.com/watch?v=liJmZ51_Oxg&ab_channel=LukasHafner
10 months ago
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The Listeria National Reference Center and WHO Collaborating Center, and many more!
10 months ago
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5/6 It also sheds light on the mechanism by which certain Listeria monocytogenes clonal complexes are more virulent, host associated, and clinically associated than others, as we also reported
www.nature.com/articles/s41...
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Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence - Nature
Studies in a mouse model of neurolisteriosis show that the effector protein InlB produced by Listeria monocytogenes protects infected monocytes in the host from T cell-mediated cell death, and thereby...
https://www.nature.com/articles/s41586-022-04505-7
10 months ago
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4/6 This unique overarching mechanism, which is unexpected, explains the overall virulence heterogeneity of Listeria monocytogenes species - from isolates to lineages, as we had reported
www.nature.com/articles/ng....
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Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity - Nature Genetics
Marc Lecuit, Sylvain Brisse and colleagues combine Listeria monocytogenes population genomic data with human epidemiological and clinical data to study human listeriosis. They report new putative viru...
https://www.nature.com/articles/ng.3501
10 months ago
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3/6 Here, we have identified a new mechanism that explains virulence heterogeneity, not by gene content but by the differential regulation of core virulence genes, driven by differential stress response.
10 months ago
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👏👏👏Congratulations to Lukas & all co-authors
10 months ago
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