Gina DeNicola
@ginadenicola.bsky.social
📤 2491
📥 758
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Redox biology and cancer metabolism @ Moffitt Cancer Center. Views my own.
The best compliment 😁
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about 2 months ago
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Katsu Funai
2 months ago
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
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Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
https://www.nature.com/naturecareers/job/12844064
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Suayb Üstün
3 months ago
Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for
#ECRs
working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details!
jobs.ruhr-uni-bochum.de/jobposting/f...
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W1TTW2 Professorship in Membrane Biology (m/f/d)
https://jobs.ruhr-uni-bochum.de/jobposting/ff10d2bfa479beb58d64ddf644d5b26c3263baa40?ref=homepage
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Soni Lacefield
2 months ago
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add!
apply.interfolio.com/171438
@dartmouthbcb.bsky.social
@futurepislack.bsky.social
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Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
https://apply.interfolio.com/171438
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Johanna Joyce
3 months ago
A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪 Up to 3.25 million euro in support 🤩
#GlobalTalentIreland
#Research
#Ireland
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Karolinska Institutet
3 months ago
Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions:
ki.se/en/about-ki/...
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Katsu Funai
4 months ago
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
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Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355
The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...
https://jobs.sciencecareers.org/job/674355
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Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here:
moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...
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Tenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cancer Center CareersTenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cance...
Working at Moffitt Cancer Center is both a career and a mission. All employees are dedicated to patient care, research and education to advance our fight against this disease.
https://moffitt-cancer-center-careers.hctsportals.com/jobs/1883440-tenure-earning-assistant-member-metabolism-and-physiology-faculty
3 months ago
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Brent Stockwell
3 months ago
Thanks to James Olzmann and Scott Dixon for organizing a fantastic
#faseb
#ferroptosis
meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one!
@olzmannlab.bsky.social
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Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful!
3 months ago
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Mara Sherman
4 months ago
To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨
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Elizabeth McKenna
4 months ago
It's my first
#newPI
roll call on BlueSky! Calling all new
#cancer
PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃
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Jeremy Berg
4 months ago
IMPORTANT IMPORTANT IMPORTANT IMPORTANT Please watch the workshop video and COMMENT by 5:00 Monday 7/14 This is the source of the "no more model organism only grants in NIH-funded research" decree.
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New work from
@karrethlab.bsky.social
!
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5 months ago
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bioRxiv Cancer Bio
5 months ago
FRA1 drives melanoma metastasis through an actionable transcriptional network
https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1
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Christian Frezza
6 months ago
Unravelling cysteine-deficiency-associated rapid weight loss
www.nature.com/articles/s41...
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Unravelling cysteine-deficiency-associated rapid weight loss - Nature
Conditional cysteine restriction in mice causes substantial weight loss, exceeding that seen with essential amino acid restriction, by activating the integrated stress and oxidative stress respon...
https://www.nature.com/articles/s41586-025-08996-y
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Great work by
@rushika-perera.bsky.social
!
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6 months ago
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Jeremy Berg
6 months ago
REMINDER.....REMINDER......REMINDER 3 DAYS LEFT TO COMMENT ON SCHEDULE F 1/n
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Journal of Cell Science
6 months ago
Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research.
journals.biologists.com/jcs/article/...
#JCSMitoSI
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So excited for this!
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6 months ago
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MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues.
www.nature.com/articles/s41...
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Spatial mapping of the brain metabolome lipidome and glycome - Nature Communications
Clarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed reg...
https://www.nature.com/articles/s41467-025-59487-7
6 months ago
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Journal of Cell Science
6 months ago
In their Tools & Resources article, Corey Cunningham
@cnfxc.bsky.social
Jared Rutter
@rutterlab.bsky.social
@uofubiochem.bsky.social
& team present their dual-purification system to isolate mitochondrial subpopulations.
journals.biologists.com/jcs/article/...
#JCSMitoSI
#OpenAccess
#Mitochondria
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🚨New paper alert! Led by former undergrad Amanda Sherwood
@tophinogenesis.bsky.social
(now PhD student at Northwestern), Amanda asked whether the glutathione or thioredoxin systems are necessary for NRF2's tumor-promoting effects in the lung.
www.sciencedirect.com/science/arti...
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Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression
Redox regulators are emerging as critical mediators of lung tumorigenesis. NRF2 and its negative regulator KEAP1 are commonly mutated in human lung ca…
https://www.sciencedirect.com/science/article/pii/S2213231725001661?via%3Dihub
6 months ago
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That's a wrap on the 2025 Cancer Metabolism Showcase. With everything going on it was so great to hear a fantastic career keynote from Jeff Rathmell and awesome talks and posters from students and postdocs! Hats off to
@harrislab.bsky.social
for running the show.
6 months ago
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Gina DeNicola
James Olzmann
6 months ago
Reminder: The 1st FASEB
#Ferroptosis
Meeting is this summer! Spectacular speaker lineup + short talks selected from submitted abstracts. It is going to be awesome! Trainees, newcomers & all interested are welcome! 📅 Abstract deadline: June 1, 2025.
shorturl.at/QA6T1
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David MacPherson Lab
6 months ago
Our latest, in Science Advances: In vivo CRISPR screen revealed sgRNAs that switch chemosensitive SCLC PDXs to become resistant.We validated KEAP1 as key hit and found KEAP1 alterations in IMpower133 trial, where active NRF2 links to reduced survival in chemo arm
www.science.org/doi/10.1126/...
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Aaron Quinlan (he/him)
6 months ago
The Department of Human Genetics at the University of Utah is sponsoring the Rising Stars in Genetics and Genomics symposium! - We are seeking nominations bu June 1. - September 18-19, 2025 - Please share with the star postdocs that you know.
docs.google.com/forms/d/e/1F...
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FASEB
7 months ago
#FOLSCR
is a new conference exploring all aspects of a form of cell death that results from iron accumulation and lipid peroxidation. Hear keynotes
@ginadenicola.bsky.social
and
@brentstockwell.bsky.social
with organizers Scott Dixon and
@olzmannlab.bsky.social
. Save your space:
buff.ly/MmJsYQq
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Jeremy Berg
7 months ago
ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n
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Christian Frezza
7 months ago
Targeted tumor therapy with L-cyst(e)ine-addicted bacteria-nanodrug biohybrids: Cell Metabolism
www.cell.com/cell-metabol...
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Targeted tumor therapy with L-cyst(e)ine-addicted bacteria-nanodrug biohybrids
Wang et al. advance bacteria-based metabolic therapy by developing DL@SFEc+ through dual-selection evolution. The evolved SFEc+ significantly enhances CySS uptake and desulfhydrase activity. Combined ...
https://www.cell.com/cell-metabolism/fulltext/S1550-4131%2825%2900115-9
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Eric Topol
7 months ago
Discovery of a gut-joint axis pathway and the salutary role of GLP-1 for "wear and tear" arthritis. New
@science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
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Liron Bar-Peled
8 months ago
I’m excited to share the latest work from our lab, led by a group of three amazing scientists: Junbing Zhang, Yousuf Ali and Harrison Chong, who describe @nature the discovery of a ROS sensor, VPS35, which links cytosolic H2O2 levels to regulation of mitochondrial translation and
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Oxidation of retromer complex controls mitochondrial translation - Nature
Systematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive ox...
https://www.nature.com/articles/s41586-025-08756-y
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Christian Frezza
8 months ago
The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism researchhttps://
www.nature.com/articles/s42255-025-01237-6
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The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research - Nature Metabolism
This broad group of authors summarizes the impact of circadian factors on metabolic biology and offers recommendations on how to account for and report biological, environmental and experimental facto...
https://www.nature.com/articles/s42255-025-01237-6
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Science Magazine
8 months ago
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more in this week's issue:
scim.ag/3FA3Ygq
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Abstracts are due TOMORROW! Please share!
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8 months ago
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What's better than spatial metabolomics? Spatial metabolomics in 3D! New from Ramon Sun and colleagues, a 3D map of the brain metabolome using AI, with an interactive database to explore.
www.nature.com/articles/s42...
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AI-driven framework to map the brain metabolome in three dimensions - Nature Metabolism
This study presents MetaVision3D, a pipeline to integrate mass spectrometry imaging sections into 3D reconstructions of metabolomic maps. The authors also provide a comprehensive 3D metabolome atlas o...
https://www.nature.com/articles/s42255-025-01242-9
8 months ago
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DeBerardinis Lab at UT Southwestern Medical Center
8 months ago
1/Happy to share a new paper reporting a metabolic approach to radiosensitization in lung cancer, from Rachel Chiang, Faith Zhang and colleagues at UT Southwestern Radiation Oncology and
@cri-utsw.bsky.social
www.science.org/doi/10.1126/...
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Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair
Genetic screen finds lipoylation as a target to improve radiation success in lung cancer by blocking DNA damage repair.
https://www.science.org/doi/10.1126/sciadv.adt1241?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
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Fascinating work from MALDI master Ramon Sun and collaborators on glycogen metabolism in NSCLC. A real tour de force and such beautiful images 😍
www.nature.com/articles/s42...
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Glycogen drives tumour initiation and progression in lung adenocarcinoma - Nature Metabolism
Clarke, Hawkinson and colleagues study the contribution of glycogen accumulation in the onset and progression of lung cancer.
https://www.nature.com/articles/s42255-025-01243-8
8 months ago
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New toy installed and everyone trained this week!
8 months ago
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Gina DeNicola
Valerie Horsley
9 months ago
Please share:
@delauro.house.gov
is cochair of the US House Congressional Rapid Response Task Force and Litigation Working Group. They are looking for instances where the impoundment and restriction of NIH/NSF funds is having a negative impact. Submit examples here
delauro.house.gov/constituent-...
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2025 Federal Financial Assistance Freeze
On Monday, January 27th, 2025, President Trump issued an order to freeze virtually all of approved and legally required federal funding.
https://delauro.house.gov/constituent-services/2025-federal-financial-assistance-freeze
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Scott Delaney
9 months ago
NIH indirects case update: Hearing ongoing now, and I'll try to live tweet some notable exchanges. Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides: (I'm paraphrasing here)
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Lucas Sullivan
9 months ago
Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation.
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"Here, using 18 single, double and triple whole-body and tissue-specific knockout and mutant mice..."
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9 months ago
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Josh Gerstein
9 months ago
BREAKING: Federal judge in Boston broadens block on Trump's NIH grant 15% overhead limit (indirect cost rates) to all recipients nationwide. Doc:
www.documentcloud.org/documents/25...
#TROpalooza
ain't done
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AAMCOrd021025
https://www.documentcloud.org/documents/25518135-aamcord021025/
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STAT
9 months ago
#BREAKING
- 22 states sue to block Trump administration cuts to NIH research payments
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22 states sue to block Trump administration cuts to NIH research payments
Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead
https://buff.ly/3WOW4VV
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Aidan Milliff
9 months ago
Here's a good infographic from AAUP on what indirect costs fund. It's a lot of important things!
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Study sections are back on this week
9 months ago
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Fendt Lab
9 months ago
We are looking for PhD students and/or postdocs that want to join us to study the metabolism of metastasizing cancer cells with cutting-edge spatial and single cell technologies.
fendtlab.sites.vib.be/en
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Isaac Harris
10 months ago
I’m really proud to announce the 2025 Cancer Metabolism Showcase and Workshop, May 5th and 6th, 9:30 AM - 3 PM EST. This year, our Keynote Speaker is Dr. Jeffrey Rathmell from VUMC. I'm excited to come together, talk science, and support researchers in our field.
www.cancermetabolismshowcase.org
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9:30 AM - 3 PM EST, May 5th and 6th, 2025
https://www.cancermetabolismshowcase.org
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Our lab's first paper of 2025. With
@christhechang.bsky.social
we find that NRF2 active lung cancer cell lines suppress labile copper and are vulnerable to copper chelation (1/3).
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10 months ago
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