Our work detailing the metabolic roles of serum for cancer cell proliferation is now out at JBC, @asbmbjournals.bsky.social! Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process. See here: www.sciencedirect.com/science/arti...

Check out this great interview with a true rising star in metabolism research (and lab alumni)! 🙌

Our paper on regulation of BCAA catabolism by mitochondrial calcium signaling is out! Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma | Science Advances www.science.org/doi/10.1126/...

Mass Spec xkcd.com/3094/

Niemi lab graduate student Hannah Pletcher recently joined @prelights.bsky.social and wrote nice highlight of recent work from @lucasbsullivan.bsky.social - check it out here!

Our latest, in Science Advances: In vivo CRISPR screen revealed sgRNAs that switch chemosensitive SCLC PDXs to become resistant.We validated KEAP1 as key hit and found KEAP1 alterations in IMpower133 trial, where active NRF2 links to reduced survival in chemo arm www.science.org/doi/10.1126/... 1/2

Overjoyed to have the opportunity to present my work orally at the Cancer Metabolism Showcase! Hope to see you there virtually!

From Nobel prize winning cancer researcher Bill Kaelin Killing the Science Golden Goose - The American Journal of Medicine www.amjmed.com/article/S000...

Obliteride registeration opens today!!! Join the @lucasbsullivan.bsky.social team and help to CURE CANCER FASTER! See you August 9th at the starting line!! @obliteride.bsky.social #Obliteride #Obliteride2025 secure.fredhutch.org/goto/sulliva...

Poster is printed! Looking forward to going to the Keystone Tumor Metabolism meeting next week in Vancouver. Come talk to me about NRF2, cysteine, and novel metabolite discovery! #KSTumorMetab25 #cancermetabolism #keystonesymposia

happy to share our forum now online @Cell_Metabolism! fun for us (Guy & myself) to collaborate with @dfazakerley.bsky.social, Joycelyn, & Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! www.cell.com/cell-metabol...

We were delighted to have @king5news.com.web.brid.gy visit us in the Termini Lab to discuss how NIH funding cuts could affect cancer research: m.youtube.com/watch?v=Szo9... We NEED indirect costs to provide funding needed complete research studies that will lead to life saving discoveries.

Next, our 2nd preprint of the week (!), this one driven by @madelouhart.bsky.social Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability. Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!

Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation.

See you next week for Oliver Newsom’s dissertation defense! Title: No Fat Chance: albumin-associated lipids are critical for culture success Lab: Sullivan Lab, FH (@lucasbsullivan.bsky.social When: Thurs, Feb. 13, 1:30pm PDT Where: FH Sze Suites, Thomas Building & Zoom (email [email protected] for link)

I’m really proud to announce the 2025 Cancer Metabolism Showcase and Workshop, May 5th and 6th, 9:30 AM - 3 PM EST. This year, our Keynote Speaker is Dr. Jeffrey Rathmell from VUMC. I'm excited to come together, talk science, and support researchers in our field. www.cancermetabolismshowcase.org

But…..ok, ok, I’m convinced. Elegant and definitive. www.science.org/doi/10.1126/...

Registration is open for #METPHYS2025! www.sablesys.com/metphys2025-...

I have curated a second "metabolism" starter pack, as the first quickly got full. Please have a look, and I am happy to add others (sorry for those who may appear in both): go.bsky.app/CH1MctZ

Updated extensive starter pack for #cancermetabolism and #mitochondrialbiology go.bsky.app/VavECSX