Genetic Drivers of Sensitivity or Resistance to RAS(ON) Multi-Selective Inhibitors in NRAS-Mutated Melanoma https://www.biorxiv.org/content/10.64898/2025.12.18.695203v1

From the biology on melanocytes to pigmentation conditions and melanoma - we have it all! Join us in Tampa in March 2026 to learn the latest in the pigment cell field (and escape the cold) at the Annual Meeting of the Pan-American Society for Pigment Cell Research

Interested in anti sense #RNA functions and their contribution to #melanoma formation? Check out our latest paper: CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma: Cell Reports www.cell.com/cell-reports...

Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!

My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...

With the NCI payline lowered to 4th percentile, this unfortunately did not age well

Fundable R01 score 🥳

Another preprint from our group. Here we show that FRA1 is a potent driver of #melanoma metastasis and inhibiting some of FRA1's transcriptional targets diminishes dissemination

Preprint alert: check out our new genetically engineered mouse model of uveal melanoma, which recapitulates many aspects of the human disease including phenotypic plasticity

Indeed, fucked we are

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

Gave a talk at the University of Louisville a few weeks ago and received this thank you gift in the mail today. My first Louisville Slugger - so cool!

We wrapped up our final day of #AMC25 on Saturday! Four days of insightful discussions, collaboration, & cutting-edge research. Grateful to everyone who joined us in DR to share insights, engage in conversations & foster collaborations. Until next time!🐭☀️🌴

I’ll be in DC March 7th at the StandUpForScience rally. See you there! If you can’t make it to DC there will be a StandUpForScience rally in a city near you. @standupforscience.bsky.social

Anyone else use 'please' and 'thank you' when entering AI prompts? I hope my life will be spared when AI takes over...

Some study sections seemed to have happened this week - one ND (R01) and a 7%ile (R21). But are June council meetings going to be on?

Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify Sign the Petition: chng.it/kK2HMP5pGk "Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."

Massive work from Jess Spinelli's lab at UMASS demonstrating a SECOND electron carrier in the mammalian ETC: www.cell.com/cell/fulltex...

4 papers submitted - a busy start to the year. Let's hope 2025 won't be the year of rejections 😁

New preprint from the lab just posted to bioRxiv. Our first foray into antisense RNAs, led by postdoc Manon Chadourne, with implications for mRNA translation. Great collab with Alex Jaeger and his lab!

We are recruiting a postdoc to join our team (myself, Boris Bastian, and Iwei Yeh) at UCSF to develop a pre-cancer atlas of skin cancer -- part of the Human Tumor Atlas Network (#HTAN). #CancerEvolution #Bioinformatics. Interested? Email resume and cover letter to me.

November has been busy, but I'm pleased to finally share our recent paper in Cancer Research: PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability aacrjournals.org/cancerres/ar... Congrats to grad student Neel! A short 🧵 of what we found.

We are hiring! We are looking for a Project Scientist to be in charge of the day-to-day operation of our tumor organoid pipeline. Come join our team of rare cancer aficionados looking to leverage organoids for functional precision medicine. Apply by November 24th! recruit.apo.ucla.edu/JPF09960

We're looking to recruit a postdoc with expertise in RNA biology to join our glyco-RNA team. Please share. moffitt-cancer-center-careers.hctsportals.com/jobs/1808511...

hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...

🚨 Update for #RNA science fans: I checked on #Bsky registry, and here is a 'condensate' (😆) of all #RNA #RNAsky starter packs so far: 1. General RNA biology #1 go.bsky.app/RN6HnZp

Thought all would be better here but alas, proofs are still due back in 48hrs

Here's the #Cancer #Research #2 starter pack 🤩 Researchers, oncologists, patient advocates & more -working across all aspects of cancer research and treatment 🧪🔬⚕️ I also tried to give some exposure to #PhD #students & #postdocs - randomly picked from followers of me or my lab! go.bsky.app/6EcjWNA