⚕️Ein Team der Pathologie der Uniklinik Köln hat das agentenbasierte KI-System SPARK entwickelt. Es verknüpft mehrere spezialisierte Algorithmen zu einem koordinierten System, das eigenständig biologische Hypothesen generieren, verfeinern und in analytische Werkzeuge umsetzen kann. ➡️ uni.koeln/BSZ8B

New preprint from the lab! Close collaboration with Silvia von Karstedt @vonkarstedtlab.bsky.social and her lab. We find that #SCLC cells are strikingly dependent on exogenous cysteine #LungCancer #CancerMetabolism #Ferroptosis 🧵 biorxiv.org/content/10.64898/2026.03.27.714827v1

Ever wondered how cellular #metabolism, #ROS, cellular confluence and #Ferroptosis are connected? Read our new study with theoretical physicist Johannes Berg @unicologne.bsky.social @cecad.bsky.social @uniklinikkoeln.bsky.social @dtg-cologne.bsky.social www.frontiersin.org/journals/cel...

🫁 Was macht das kleinzellige Lungenkarzinom (SCLC) so aggressiv? Forscher unter Leitung von @vonkarstedtlab.bsky.social vom @cecad.bsky.social / @unicologne.bsky.social haben einen neuen Mechanismus entdeckt, der dem #Lungenkrebs bei seiner Ausbreitung im Körper hilft. #SCLC

Inflammation fuels one of the most aggressive forms of cancer www.idw-online.de/-DS52AA

A caspase 8 deletion #SCLC mouse model promotes a neuronal progenitor-like cell state and pre-tumoral immunosuppression triggered by #necroptosis that promotes metastasis @vonkarstedtlab.bsky.social @unicologne.bsky.social @dtg-cologne.bsky.social @cecad.bsky.social doi.org/10.1038/s414...

What a nice way to end 2025: absence of caspase 8 in #sclc leads to neuronal-like reprogramming and promotes #metastasis via #necroptosis driven #inflammatory response. Congratulations to Ariadne and collaborateurs @unicologne.bsky.social @dtg-cologne.bsky.social ! www.nature.com/articles/s41...

Happy to share an incredibly efficient collaboration with @gianmaria-liccardi.bsky.social : Ibrutinib cooperates with #ferroptosis induction to kill #dlbcl www.nature.com/articles/s41...

The study titled “Functional synapses between neurons and small-cell lung cancer” was published in @nature.com 👇 www.nature.com/articles/s41... #unicologne #uniklöln @cecad.bsky.social #sclc #lungcancer #cancerresearch

Signalling between neurons and tumour cells in the lung and brain promotes the growth of small-cell lung cancer go.nature.com/4gzoMmI

Happy to start at Bluesky with a post on our recent manuscript at @nature.com: www.nature.com/articles/s41... Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.

Hot topic in a hot environment! #FASEB @faseborg.bsky.social #Ferroptosis meeting organized by @olzmannlab.bsky.social and Scott Dixon is the place to be!

Come join us at this year's #FASEB conference on #Ferroptosis ! events.faseb.org/event/ferrop...

Today back to work from #maternityleave I found this left by my lovely team in my office @cecad.bsky.social

👏 Congratulations to Professor Aleksandra Trifunovic on receiving the Max Delbrück Research Prize 2025 from the University of Cologne for her groundbreaking work on #mitochondria, #aging, and cellular stress responses. A proud moment for #CECAD! ➡️ uni.koeln/Y6WSC @unicologne.bsky.social

What do cells undergoing #ferroptosis #celldeath release? Read all about it in our atlas on ferroptosis #secretomes out now in Cell Death and Differentiation #CDDpress Great collaboration with @cecad.bsky.social @frezzalab.bsky.social @kreuzaler.bsky.social @almutschulze.bsky.social rdcu.be/ejp9C

And this paper is coming to you live from #maternityleave with the right supportive network! Just wanted to encourage #womeninscience #youngparents

Ever wondered how #mitochondria fragmentation comes about during #ferroptosis ? Read our new paper on Drp1-mediated promotion of ferroptotic #celldeath. Great @cecad.bsky.social collaboration with Ana Garcia Saez! rdcu.be/d7L66

Very pleased to see our latest study published at CDDpress. We show that #Seratrodast, an approved drug, is a suppressor of #ferroptosis by inihibiting lipid peroxidation. Thanks to Jule, Wulf, and the rest of the team! www.nature.com/articles/s41...

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

Something always suspected now out in @natureportfolio.bsky.social Take home mesage: eat and be merry for life is too short to outsmarten #epigeneticmemory

Very interesting read for #SCLC aficionados!