Andreas Linkermann
@linkermannlab.bsky.social
š¤ 117
š„ 146
š 10
Chair 5th Med Dept UMM, Heidelberg University Kidney Transplantation and Cell Death Biology
pinned post!
Happy to start at Bluesky with a post on our recent manuscript at
@nature.com
:
www.nature.com/articles/s41...
Great collaboration with cool scientists such as
@theprattgroup.bsky.social
,
@fedorovalab.bsky.social
and many who do not (yet) have a Bluesky account.
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Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature
17Ī²-oestradiol establishes an anti-ferroptotic state in female kidney tubules.
https://www.nature.com/articles/s41586-025-09389-x
5 months ago
4
36
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reposted by
Andreas Linkermann
Nature
17 days ago
Nature research paper: Erythropoietin receptor on cDC1s dictates immune tolerance
go.nature.com/496nEob
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Erythropoietin receptor on cDC1s dictates immune tolerance - Nature
The tolerogenic activityĀ of type 1 conventional dendritic cells (cDC1s) is determined by EPOR, which is preferentially expressed in cDC1s and inducesĀ antigen-specificĀ FOXP3-expressing regulatory T cells.
https://go.nature.com/496nEob
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reposted by
Andreas Linkermann
Nature
about 1 month ago
Obituary: David Baltimore (1938-2025) virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
go.nature.com/443Vojo
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David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.
https://go.nature.com/443Vojo
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Secondary Necrosis Following CaspaseāActivation can Occur Independently of Gasdermin E - Gavali - Advanced Science - Wiley Online Library
advanced.onlinelibrary.wiley.com/doi/10.1002/...
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Secondary Necrosis Following CaspaseāActivation can Occur Independently of Gasdermin E
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202507381
2 months ago
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Congrats to the wonderful Sid Balachandran and team!
www.nature.com/articles/s41...
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Host cell Z-RNAs activate ZBP1 during virus infections - Nature
Nature - Host cell Z-RNAs activate ZBP1 during virus infections
https://www.nature.com/articles/s41586-025-09705-5
3 months ago
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reposted by
Andreas Linkermann
Molecular Medicine Partnership Unit
4 months ago
Registration is open: register for the first
#MMPUResearchDay
taking place in
#Mannheim
at
#CubexOne
on Oct 13, 2025. A great line-up of scientists from
#MMPU
,
#EMBL
,
#UMM
,
#UKHD
.
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Very pleased to share this "spotlight" in Trends in Endocrinology and Metabolism which refers to our recent work.
www.sciencedirect.com/science/arti...
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Hydroxyestradiol alleviates acute kidney injury via blockade of ferroptosis
The molecular mechanisms underlying sex differences in acute kidney injury (AKI) remain incompletely understood. In a study recently published in Natuā¦
https://www.sciencedirect.com/science/article/abs/pii/S1043276025001936
4 months ago
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Here is a "highlight" on our recent work written by Boyi Gan for Cell Death and Differentiation:
www.nature.com/articles/s41...
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Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury - Cell Death & Differentiation
Cell Death & Differentiation - Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury
https://www.nature.com/articles/s41418-025-01573-w
4 months ago
2
5
0
www.aerzteblatt.de/news/warum-f...
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Warum Frauen seltener ein akutes Nierenversagen erleiden ā Deutsches Ćrzteblatt
https://www.aerzteblatt.de/news/warum-frauen-seltener-ein-akutes-nierenversagen-erleiden-a027d07e-8183-42a3-940e-07f0837d97fe
4 months ago
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This refers to our recent manuscript. Estrogen-powered kidney protection | Science Signaling
www.science.org/doi/10.1126/...
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Estrogen-powered kidney protection
Estrogen protects against kidney injury through both genomic and nongenomic mechanisms.
https://www.science.org/doi/10.1126/scisignal.aeb6175
4 months ago
1
4
1
STING drives
#necroptosis
, and hereās how it does it! Congratulations to
@gianmaria-liccardi.bsky.social
and his amazing team!
www.nature.com/articles/s41...
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STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD - Nature
Nature - STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD
https://www.nature.com/articles/s41586-025-09536-4
5 months ago
1
3
2
Happy to start at Bluesky with a post on our recent manuscript at
@nature.com
:
www.nature.com/articles/s41...
Great collaboration with cool scientists such as
@theprattgroup.bsky.social
,
@fedorovalab.bsky.social
and many who do not (yet) have a Bluesky account.
loading . . .
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature
17Ī²-oestradiol establishes an anti-ferroptotic state in female kidney tubules.
https://www.nature.com/articles/s41586-025-09389-x
5 months ago
4
36
17
reposted by
Andreas Linkermann
Ubellacker Lab
5 months ago
Hot off the presses! Was an honor to team up with Scott Dixon
@stanforduniversity.bsky.social
on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic.
rdcu.be/eBbqV
add a skeleton here at some point
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