There hasn't previously been a treatment vs pancreatic cancer this successful. Striking improved (a doubling) survival results @nejm.org and @ascocancer.bsky.social published today with daraxonrasib, which also became available via an FDA-approved early access program nejm.org/doi/full/10....

1/3 Thrilled to see our paper led by Kirandeep Deol is out in Nature Structural & Molecular Biology! CRISPR screens to uncover a role for vitamin B2 metabolism in stabilizing FSP1 via FAD, revealing a new way vitamins regulate ferroptosis. www.nature.com/articles/s41...

Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out thttps://www.nature.com/articles/s41556-025-01856-x

Our preprint "#miR940 suppresses #ferroptosis by controlling expression of key regulatory genes" is now available. A true collaborative effort 🤩 Thanks to the team and all collaborators. Full preprint: www.biorxiv.org/content/10.6... @helmholtzmunich.bsky.social @columbiauniversity.bsky.social

Dr. Vincendeau @m-vincendeau.bsky.social von @helmholtzmunich.bsky.social untersucht in ihrem AFI-Projekt, welche Virusreste im Erbgut mit Alzheimer in Zusammenhang stehen könnten und welche Mechanismen dadurch ausgelöst werden. ▶️ Mehr Infos zum Projekt gibt es im Video

Thanks to @afi-ev.bsky.social for funding our project @helmholtzmunich.bsky.social ! Excited to delve into new aspects of Alzheimers research! www.alzheimer-forschung.de/forschung/fo...

New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @dannomura.bsky.social and huge credit to grad student superstar Sydney Tomlinson! www.biorxiv.org/content/10.1...

Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis. www.nature.com/articles/s41...

I was honored to give the L. Carroll King Memorial Lectures at Northwestern University, sponsored by the Chemistry Department. Professor King was a pioneering researcher and #teacher who joined Northwestern’s faculty in 1942. He was active in advancing ideas about chemical #education

I’m excited to lead this new journal that will focus on how cells interact with their environment. We are assembling a top tier editorial board, key partnerships, and looking to be the primary forum for the rapidly growing field of spatial biology.

Check out our new paper 🎉. Thanks to everyone who was involved 🙏🏻.

Humbled and honored to receive the 2026 Avanti Award in Lipids from ASBMB! Grateful to my exceptional lab, mentors, and collaborators for their support and inspiration. Excited to keep pushing the boundaries of lipid biology and therapeutics! www.asbmb.org/asbmb-today/...

Tenure track position alert! Assistant Professor of Molecular Therapeutics in MCB @UCBerkeley. Apply and come be our colleague! 🎉 aprecruit.berkeley.edu/JPF05098

Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV

Happy to start at Bluesky with a post on our recent manuscript at @nature.com: www.nature.com/articles/s41... Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.

📢 Our August issue is online! 🎨 The cover highlights a Feature Review from Stephanie Rosswag de Souza, @gzaffagnini.bsky.social, and @bokelab.bsky.social on how proteostasis functions in cellular dormancy across a number of examples, from yeast to adult quiescent stem cells and vertebrate oocytes.

Don't miss out on other great Review content! 📝 A Review from @angelifriedmann.bsky.social, @k-hadian.bsky.social, et al details the metabolic code of ferroptosis 📝 @damelab.bsky.social et al describe how prokaryotes and viruses possess histone-mediated chromatin organization (1/n)

🚨Preprint alert 🚨 We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants. www.biorxiv.org/content/10.1.... pls check @olzmannlab.bsky.social www.biorxiv.org/content/10.1... #ferroptosis #FSP1 #antioxidants

Fantastic lab with exciting science! Strong recommendation. Apply 👇🏻

A new postdoc position in our group will open early next year — looking for candidates with a proven track record & relevant experience. If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome. pls share 🙏

Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

We're hiring postdoctorate fellows in covalent chemical biology - pass the word. careers.dana-farber.org/job/11940/po... careers.dana-farber.org/job/11941/po...

Online now - the Review "The metabolic code of #ferroptosis: nutritional regulators of cell death" from @angelifriedmann.bsky.social @k-hadian.bsky.social and colleagues. #LipidPeroxidation #Nutrients #Metabolites #Vitamins #Lipids Read it here 👉 authors.elsevier.com/sd/article/S...

New review together with @k-hadian.bsky.social group- Have fun reading! #ferroptosis #nutrition #celldeath www.sciencedirect.com/science/arti...

Virologin Michelle Vincendeau @m-vincendeau.bsky.social hat uns ein paar Fragen zu ihrer Forschung mit #Organoiden beantwortet und beschreibt, wie sie damit den Einfluss bestimmter Viren auf die Gehirnentwicklung untersucht. 🧠 #HERVs @www.helmholtz-munich.de 👉 www.infectnet.org/web/blog-pos...

👩‍🔬 Die Münchner Virologin Dr. Michelle Vincendeau @m-vincendeau.bsky.social erforscht mit Gehirn-Organoiden die Rolle von Humanen Endogenen Retroviren ( #HERVs ) bei der Gehirnentwicklung und der Entstehung von neurodegenerativen Erkrankungen. 🧠 👉 www.helmholtz-munich.de/en/viro/rese...

Bei unserem neuen Life Science Institut #AITHYRA gibt es den nächsten Meilenstein: Georg Winter wird neben @mmbronstein.bsky.social Direktor. Damit ist das Führungsteam komplett. Welcome on Board, Georg! www.oeaw.ac.at/news/oeaw-ge...

Kaiserschmarrn is enjoyable at any altitude and in any season

Something that qualifies as big news from my side: I am very happy and excited to announce that I have been appointed as Life Science Director at AITHYRA, a new Research Institute for Biomedical Artificial Intelligence. Find out more in the link and 🧵 below lnkd.in/d_HaGuSE

@georgwinter.bsky.social wird neuer Life Science Direktor des #AITHYRA-Instituts 🥳 Der international ausgezeichnete Biochemiker verstärkt somit das Team rund um KI-Direktor @mmbronstein.bsky.social und Administrative Direktorin Anita Ender. Mehr dazu ⤵️ www.oeaw.ac.at/news/oeaw-ge...

Only a few days left to register. We are loving the abstracts you are submitting!

We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...

A few more days left to register!

Curious about the interplay between #apoptosis and #ferroptosis and their role in cytotoxic stress, whether induced by drugs or serum depletion? Check out our latest paper in #NatureCommunications. rdcu.be/ebbYX @unigraz #CellDeath #LipidMetabolism

Herzlichen Glückwunsch, Matthias Tschöp. Der derzeitige CEO des Helmholtz Zentrums München wurde heute zum neuen Präsidenten der LMU gewählt. Seine sechsjährige Amtszeit beginnt am 1. Oktober 2025. www.lmu.de/de/newsroom/...

I am excited to share our latest paper @Nature where we construct a hi-res spatial map of the human hypothalamus, the brain region central in appetite control. It is a collaboration between @IMS_MRL @Cambridge_Uni & @MPI_Metabolism www.nature.com/articles/s41...

Look forward to welcoming all participants in Frankfurt for some exciting science, building networks and having a good time 🤗🍀

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

Tour de force! @metorrespadilla.bsky.social & team develop Smart-seq+5′ to map TSS in single embryos with unprecedented res revealing plethora of TE-driven transcripts in 5 mammal species. Some surprisingly old & conserved. Treasure trove of new biology for yrs to come! www.cell.com/cell/fulltex...

It is great to see #NatureReviewsDrugDiscovery highlighting our work on Hi-Q brain #organoids and their application in disease modeling and drug screening, which we recently published in #NatureCommunications. www.nature.com/articles/d41... @naturerevdrugdisc.bsky.social @www.helmholtz-munich.de

It is great to see #NatureReviewsDrugDiscovery highlighting our work on Hi-Q brain #organoids and their application in disease modeling and drug screening, which we recently published in #NatureCommunications. www.nature.com/articles/d41... @naturerevdrugdisc.bsky.social @www.helmholtz-munich.de

🥹 So true

Great to see our paper in #NatureComm — a study co-led by Jay Gopalakrishnan’s lab and my lab: “Reliability of high-quantity human brain #organoids for modeling microcephaly, glioma invasion and drug screening” www.nature.com/articles/s41... @naturecomms.bsky.social @www.helmholtz-munich.de

Excited to share our new preprint! Exceptional work by @mikelangelipid.bsky.social identifies the first #LipidDroplet lipid quality control pathway! LD-localized FSP1 safeguards neutral lipids from peroxidation and prevents #ferroptosis. 🤩https://www.biorxiv.org/content/10.1101/2025.01.06.631537v1

"Patient-derived Hi-Q brain organoids can recapitulate distinct forms of genetic brain disorders" and "Hi-Q brain organoids model glioma invasion and are amenable to medium-throughput compound screening"👇

Great to see our paper in #NatureComm — a study co-led by Jay Gopalakrishnan’s lab and my lab: “Reliability of high-quantity human brain #organoids for modeling microcephaly, glioma invasion and drug screening” www.nature.com/articles/s41... @naturecomms.bsky.social @www.helmholtz-munich.de

Don’t miss it: Our 2024 Highlights Are Here!✨ From groundbreaking research to innovative breakthroughs, it’s been an incredible year at #HelmholtzMunich! 🚀 As our CEO Prof. Matthias Tschöp says: "It’s a must-see!" 👉 Watch now: t1p.de/8h5s3 #DiscoveringFutureHealth @fabiantheis.bsky.social

1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.1101/2024.12.11.627935v1

The Dept. of Biological Sciences at Columbia is searching for an #AssistantProfessor in the area of #biochemistry — submit a one-page anonymized statement of research w/app. Apply here: : apply.interfolio.com/160181

Wow! This is pretty cool. Congrats! 🥂