Pedro Friedmann Angeli
@angelifriedmann.bsky.social
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🇧🇷 expat living in 🇩🇪 Tweets in English sometimes in Portuguese - Impressum:
http://bit.ly/14S4Z8k
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Pedro Friedmann Angeli
Brent Stockwell
6 days ago
EXO Chat w/ Prof. Norbert Perrimon (Harvard/HHMI) and 1st author Dr. Myeonghoon Han, from his lab, about their EXO review on deorphanizing the secretome: where biochemistry, genetics, and AI meet.
www.sciexplor.com/exo/podcast/3
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EXO - Beyond the Cell | Science Exploration Press
https://www.sciexplor.com/exo/podcast/3
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Mathias Munschauer
7 days ago
One of the best parts of leading a department is the opportunity to recruit exceptional people who will shape its future. Today, I'm thrilled to share that we are recruiting a W3 Professor of Translational Hepatitis Virus Research at Heidelberg University.
www.nature.com/naturecareer...
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W3 Professorship in Translational Hepatitis Virus Research (m/f/d) - Heidelberg, Baden-Württemberg (DE) job with WESTPRESS GmbH & Co. KG | 12861212
The Heidelberg Medical Faculty of the University of Excellence Heidelberg is an outstanding location for innovative research, both nationally and i...
https://www.nature.com/naturecareers/job/12861212/w3-professorship-in-translational-hepatitis-virus-research-m-f-d-/?LinkSource=PremiumListing
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Pedro Friedmann Angeli
www.MitoWorld.org
21 days ago
Explore
#mitocancer
insights from
@angelifriedmann.bsky.social
&
@veraskafar.bsky.social
on how
#riboflavin
influences
#mitochondrialfunction
#ferroptosis
& strategies to block
#mitochondria
driven resistance mechanisms in cancer!
@nature.com
mitoworld.org/riboflavin-m...
#UMDF
#mitoscientists
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Riboflavin Modulates Lipid Peroxidation and Ferroptosis - MitoWorld
A multi-institute research team, led by Prof. José Pedro Friedmann Angeli, examined the activity of ferroptosis suppressor protein 1 (FSP1) in protecting against phospholipid peroxidation and ferropto...
https://mitoworld.org/riboflavin-modulates-lipid-peroxidation-and-ferroptosis/
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Pedro Friedmann Angeli
Jean-Ehrland RICCI
28 days ago
happy to share our review collection “Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities”
@oncogenesisnature.bsky.social
. A big thank you to all contributing authors. If you are interested in cancer metabolism, I encourage you to read these expert reviews. enjoy!!
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Pedro Friedmann Angeli
Julius-Maximilians-Universität Würzburg
about 1 month ago
New Paper in Science Advances: Researchers at JMU discovered that a molecule can act as a biological “double agent”: while blocking one important
#cell
process, it also disables a key protective mechanism.
#CellBiology
#Pharmakology
📸 generated with AI ➡️
go.uniwue.de/gohla-cp1
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Pedro Friedmann Angeli
Cell Chemical Biology
about 1 month ago
Online now! Online now! The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue
#chembiol
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The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue
Hinshaw et al. determine the molecular basis for TRIM21 recruitment to the nuclear pore protein NUP98, showing that an induced protein-protein interface drives the potency and selectivity of the molecular glue mechanism.
http://dlvr.it/TSlHBf
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Pedro Friedmann Angeli
about 1 month ago
“Fatty acid channelling into triglycerides and oxylipins drives ferroptosis resistance during oncogenic BRAF-induced senescence” An interesting link between lipid metabolism in OIS cells and their resistance to ferroptosis and oxidative stress ⤵️
www.nature.com/articles/s41...
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Pedro Friedmann Angeli
Jean-Ehrland RICCI
about 2 months ago
Excellent and highly insightful review - A must-read for researchers interested in lymphoma and cancer metabolism. Thank you Chris for contributing to our special issue in
@oncogenesisnature.bsky.social
on « metabolism and cancer »
www.nature.com/articles/s41...
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Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma - Oncogenesis
Oncogenesis - Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma
https://www.nature.com/articles/s41389-026-00629-x
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Pedro Friedmann Angeli
Helena Cocheme
about 2 months ago
📍 Registration is now open for this
#Redox
#BiochemicalSociety
Meeting! Excellent invited speakers, plus many slots for elevated talks from abstracts, including
#ECRs
🫵 🌍 Cambridge, UK 🗓️ 16-18 Nov 2026 ⏳ Super early bird deadline: 16 Aug 2026 🌐
bit.ly/Redox-26
#BiochemEvent
@biochemsoc.bsky.social
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Pedro Friedmann Angeli
Lucas Sullivan
3 months ago
Pleased to share our recent work out today in
@natmetabolism.nature.com
. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?
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Uproar in Germany over law requiring men get military approval for long stays abroad
www.theguardian.com/world/2026/a...
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Uproar in Germany over law requiring men get military approval for long stays abroad
Clause says those aged up to 45 may need permission from armed forces to leave country for more than three months
https://www.theguardian.com/world/2026/apr/05/uproar-germany-law-men-up-to-45-military-permission-long-stays-abroad
3 months ago
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Pedro Friedmann Angeli
Elizabeth Veal
3 months ago
If you are a postdoc or grad students that wants to be considered for a talk at the GRS then get your abstract in! (Deadline 5th April).
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Pedro Friedmann Angeli
Elizabeth Veal
5 months ago
If a week by the Mediterranean discussing the latest research Bridging Redox Chemistry to Biology, Aging and Disease sounds like a welcome escape, then this Gordon Research Conference could be for you!
www.grc.org/thiol-based-...
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2026 Thiol-Based Redox Regulation and Signaling Conference GRC
The 2026 Gordon Research Conference on Thiol-Based Redox Regulation and Signaling will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.
https://www.grc.org/thiol-based-redox-regulation-and-signaling-conference/2026/
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Pedro Friedmann Angeli
Claudia Lennicke
4 months ago
Excited to co-chair the 2026 Gordon Research Seminar (GRS) on Thiol-Based Redox Regulation & Signaling with Taylor Covington, a meeting for early career researchers in redox research 📍 Castelldefels (Barcelona), Spain ☀️ 📅 July 11–12, 2026
#Redox
#Thiols
#EarlyCareerResearchers
More details ↓
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Very grateful to receive the Deutscher Krebspreis 2026 (Experimental Cancer Research) together with Marcus Conrad. This recognition reflects the incredible efforts of our teams and collaborators over the years
@uni-wuerzburg.de
3 months ago
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Isn't this like normal?
3 months ago
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Pedro Friedmann Angeli
Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out thttps://www.nature.com/articles/s41556-025-01856-x
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Riboflavin metabolism shapes FSP1-driven ferroptosis resistance - Nature Cell Biology
After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...
https://www.nature.com/articles/s41556-025-01856-x
4 months ago
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Pedro Friedmann Angeli
Wilhelm Lab
3 months ago
Interested in investigating dietary and metabolic regulation of immune responses? We have a PostDoc and a PhD position available in the lab.
karriereamukb.de/jobs/postdoc...
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Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity - Karriereamukb | Jobs & Karriere an der Uniklinik Bonn
The following full-time (38.5 hours/week) position is to be filled as soon as possible in the Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Fri...
https://karriereamukb.de/jobs/postdoctoral-fellow-m-f-d-metabolic-and-nutritional-regulation-of-immunity/
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Pedro Friedmann Angeli
Mick Lewis 🇨🇦
4 months ago
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Pedro Friedmann Angeli
Nature Portfolio
4 months ago
A study in Nature Cell Biology identifies riboflavin, vitamin B2, as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in cancer cells. underscoring the therapeutic potential of targeting riboflavin metabolism.
go.nature.com/4blD8Gi
#medsky
🧪
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Pedro Friedmann Angeli
Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.
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4 months ago
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Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.
add a skeleton here at some point
4 months ago
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Pedro Friedmann Angeli
Julius-Maximilians-Universität Würzburg
4 months ago
#Vitamin
B2 is converted into molecules which protect cells from oxidative damage. The downside: It also protects
#cancer
cells. Scientists at the Rudolf Virchow Centre at
#JMU
discovered that. 📸 Natalie Fahmer ➡️
www.uni-wuerzburg.de/en/news-and-...
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Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out thttps://www.nature.com/articles/s41556-025-01856-x
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Riboflavin metabolism shapes FSP1-driven ferroptosis resistance - Nature Cell Biology
After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...
https://www.nature.com/articles/s41556-025-01856-x
4 months ago
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Pedro Friedmann Angeli
Nature Structural & Molecular Biology
4 months ago
New online: FAD-dependent stabilization of FSP1 promotes ferroptosis resistance
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FAD-dependent stabilization of FSP1 promotes ferroptosis resistance
Nature Structural & Molecular Biology, Published online: 13 March 2026; doi:10.1038/s41594-026-01760-4The oxidoreductase FSP1 recycles radical-trapping antioxidants that suppress oxidative lipid damage and ferroptosis. A series of genetic screens reveal a key role for the vitamin B2 metabolite flavin adenine dinucleotide in stabilizing FSP1, preventing its proteasomal degradation and promoting ferroptosis suppression.
http://dlvr.it/TRSYqQ
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Pedro Friedmann Angeli
Rune Busk Damgaard
5 months ago
🧐 What if metabolic defects are not just a consequence of inflammatory disease - but actively contribute to it? Inflammation and metabolism are deeply intertwined, but the molecular links remain unclear. Our new paper in Cell Death & Differentiation uncovers one. 🧵👇
nature.com/articles/s41...
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Pedro Friedmann Angeli
Inflammasome Lab
5 months ago
It's shaping up to be an amazing line up at the Gordon Cell Death meeting! Register now!
www.grc.org/cell-death-c...
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2026 Cell Death Conference GRC
The 2026 Gordon Research Conference on Cell Death will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
https://www.grc.org/cell-death-conference/2026/
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In 🇧🇷portuguese this will be cleanly translated to "Capitão do mato" - you cant make this stuff up...
en.wikipedia.org/wiki/Slave_c...
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5 months ago
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Pedro Friedmann Angeli
ProPublica
5 months ago
BREAKING: The two federal immigration agents who fired on Minneapolis protester Alex Pretti are identified in government records as Border Patrol agent Jesus Ochoa and Customs and Border Protection officer Raymundo Gutierrez.
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Two CBP Agents Identified in Alex Pretti Shooting
The two federal immigration agents who fired on Minneapolis protester Alex Pretti are identified in government records as Border Patrol agent Jesus Ochoa and Customs and Border Protection officer Raym...
https://www.propublica.org/article/alex-pretti-shooting-cbp-agents-identified-jesus-ochoa-raymundo-garcia?utm_source=bluesky&utm_medium=social&utm_campaign=propublica-bsky
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www.cnn.com/2026/01/22/s...
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Ai Weiwei quietly returns to China after a decade: ‘It felt like a phone call suddenly reconnecting’ | CNN
For the past 10 years the dissident artist has lived in Germany, the UK and now Portugal, never once setting foot in his native country, where people with far less controversial pasts have faced arbit...
https://www.cnn.com/2026/01/22/style/ai-weiwei-beijing-visit-hnk-intl-dst
6 months ago
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Pedro Friedmann Angeli
Holthuis Lab
6 months ago
Modern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026
meetings.embo.org/event/26-lip...
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In today’s European politics, consensus is dead, unless the topic is Greenland. Thanks, Trump.
6 months ago
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seems like the second Dark Age has officially started
6 months ago
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Pedro Friedmann Angeli
DTL
6 months ago
Tech lords lining up at the vet
scitechdaily.com/castration-l...
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Castration Linked to Increased Lifespan in Mammals
A large-scale analysis of 117 mammal species found that preventing reproduction is associated with longer lifespans, suggesting a strong link between reproductive activity and life expectancy. Why do ...
https://scitechdaily.com/castration-linked-to-increased-lifespan-in-mammals/
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Pedro Friedmann Angeli
Alicia Kowaltowski
6 months ago
The unimaginable is happening in the US government, but the muted response of Americans against it surprises me. Brazilians may have something to contribute, explaining how to organize a good Panelaço (which in English is apparently a "casserole protest"):
en.wikipedia.org/wiki/Cacerol...
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Cacerolazo - Wikipedia
https://en.wikipedia.org/wiki/Cacerolazo
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Pedro Friedmann Angeli
Kai Kupferschmidt
6 months ago
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social
as usual not pulling any punches
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Last Year, and the Year to Come
https://www.science.org/content/blog-post/last-year-and-year-come
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Things will improve in 2026 🫏
6 months ago
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Pedro Friedmann Angeli
If 2025 was a lot… here’s a reminder: keep moving, keep flowing 🌊 Happy holidays from Foz do Iguaçu 🇧🇷
6 months ago
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Pedro Friedmann Angeli
Manuel Friese
6 months ago
We are hiring dedicated and motivated new members to join our basic and clinical research team at INIMS (
www.inims.de
), Universitätsklinikum Hamburg-Eppendorf. - Medical Scientist (Postdoc) - Clinician Scientist (Neurology) Apply here:
www.uke.jobs/index.php?ac...
www.uke.jobs/index.php?ac...
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If 2025 was a lot… here’s a reminder: keep moving, keep flowing 🌊 Happy holidays from Foz do Iguaçu 🇧🇷
6 months ago
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Pedro Friedmann Angeli
GDCh Division of Biochemistry
7 months ago
We have a great line-up of speakers including: Jennifer Andexer, Helge Bode, Stephan Hammer, Akane Kawamura, Alexandria (Ali) Deliz Liang, Carina de Oliveira Mann, Stefan Raunser, Schraga Schwartz, Pierre Stallforth, Carine Tisné, Satpal Virdee, Wilfred van der Donk
#Chemistry
#Meeting
CC:
@gdch.de
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Pedro Friedmann Angeli
GDCh Division of Biochemistry
7 months ago
Are you interested in cutting-edge #Biochemistry and #ChemBio? Join us for the GDCh #Biochemistry2026 conference in Würzburg on March 16th to 18th, 2026. Registration is now open and you can submit an abstract until January 10th, 2026:
veranstaltungen.gdch...
#Biochemistry
#ChemBio?
#Biochemistry2026
/2)
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2025 feelings -
7 months ago
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www.cnn.com/2025/12/17/p...
That’s not politics. That’s basic lack of adult supervision.
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New plaques on Trump’s ‘Presidential Walk of Fame’ offer pointed descriptions of predecessors | CNN Politics
The White House has installed plaques along President Donald Trump’s “Presidential Walk of Fame,” offering descriptions of his predecessors, often written in the style of his social media posts — incl...
https://www.cnn.com/2025/12/17/politics/presidential-walk-of-fame-plaques-trump
7 months ago
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Pedro Friedmann Angeli
benderlab
7 months ago
🔬 PhD opportunities in Würzburg, Germany! The RTG 3190 is offering 11 funded PhD positions focused on thrombo-inflammation. 📅 Apply by January 16, 2026 👉 Don’t miss your chance to be part of a new DFG-funded research training group!
#platelets
#thrombo-inflammation
#inflammation
#megakaryocyte
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Pedro Friedmann Angeli
Institut Pasteur | 130 years of biomedical research
7 months ago
🔬 Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies 📅 Deadline: Feb 9, 2026 👥 2-12 years post-PhD Apply now 📝
research.pasteur.fr/en/call/crea...
#JobOpportunity
#Research
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Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
https://research.pasteur.fr/en/call/creation-of-new-junior-research-groups-at-the-institut-pasteur-call-for-applications-2026/
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Group outing - we visited Bamberg and toured the city learned a bit about it history and ended up trying some smoked bier 🙃🥓 Want to join us next time? We are currently looking for potential new colleagues PhD and Postdoc level entry - please reach to see if our research interests align!
7 months ago
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Pedro Friedmann Angeli
Christophe Zimmer
8 months ago
We have an open call for a group leader at the Rudolf Virchow Center for Integrative and Translational Bioimaging in Würzburg, Germany. Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...
Please spread the word.
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Group Leader (f/m/d) at the Rudolf Virchow Center for Integrative and Translational Bioimaging - Würzburg (Stadt), Bayern (DE) job with University of Würzburg - Rudolf Virchow Center for Integrative a...
The Rudolf Virchow Center for Integrative and Translational Bioimaging (RVZ) ist now inviting applications for the position of Group Leader (f/m/d).
https://www.nature.com/naturecareers/job/12849063
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thats the sort of news the word is needing right now
7 months ago
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Pedro Friedmann Angeli
Andrea Musacchio
7 months ago
Several people, close and distant, have reached out to me to express their concern that my critique of the LLPS field and more specifically of the role of
@hymanlab.bsky.social
is personally motivated. I thank them for expressing their concerns.
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