Excited to share our new preprint, led by Kirandeep Deol! 🤩 Genetic screens uncover mechanisms regulating FSP1 abundance in cancer. Vitamin B2 metabolism promotes FSP1 stability via FAD synth / binding, further linking nutrient metabolism to ferroptosis. www.biorxiv.org/content/10.1...

The count down has begun! 1-week until the 1st FASEB Ferroptosis conference! Looking forward to seeing everyone at the meeting. Get excited!! 🤩 events.faseb.org/event/11797f...

My third paper from grad school is out on Biorxiv! This was a fun collaboration with @olzmannlab.bsky.social where we show that Ferroptosis Suppressor Protein-1 is a better target than GPX4 because it disrupts Treg function while leaving effector T cell function intact.

New preprint w/ the Dupage lab led by @jgcastillo.bsky.social! FSP1 KO in Tregs / Tcells promotes tumor suppression, highlighting the therapeutic value potential of FSP1 inhibition. New paradigm for targeting ferroptosis in immune system (not just in cancer cells). 🤩 www.biorxiv.org/content/10.1...

FYI - We've extended abstract submission deadline to June 8. Submit soon to be considered for a short talk. Come join us at the first FASEB #Ferroptosis meeting! It's going to be awwwwesome! 🤩 events.faseb.org/event/11797f...

The world is small... Randomly found out that @mikelangelipid.bsky.social and I are both in Osaka, so we met up for some drinks and #lipidtime talk.

Our team (hsph.harvard.edu/research/ube...) is excited to have contributed to the intranodal in vivo testing of the remarkable new compound, Fentomycin-1. Congrats to team Rodriguez et al. for the implications of this work in targeting ferroptosis in cancer. Check it out here!

Excited to see our N&V w/ @mikelangelipid.bsky.social published in Nature, highlighting new work from Raphael Rodriguez and team. A heterofunctional molecule that activates lysosomal iron triggers lipid peroxidation and ferroptosis in therapy-resistant cancer cells. www.nature.com/articles/d41...

Fantastic new study from Raphael Rodriguez' lab shows that induced proximity concepts can be used to induce Ferroptosis! Inducing proximity of lysosomal iron and lipids induces lipid peroxidation! What a cool concept! Have a look at our News/Views with @olzmannlab.bsky.social shorturl.at/cbc8D

**Rapid Response Bridge Funding Program** -- $25,000 grants earmarked for early-career researchers whose NSF-funded research on STEM and education has just been terminated. www.spencer.org/grant_types/... hub.jhu.edu/2025/04/28/j... Thanks @lizneeley.bsky.social !

Join for the first FASEB Ferroptosis conference in the US this July! This stellar speaker line up brings together almost all leaders in the field!

Join us next week: Bits and Bites on May 8, from 9-1pm, on Zoom. Registration and payment here: na.eventscloud.com/ereg/index.p... We will present and discuss the best practice for #Quality Control and Quality Assurance. #metabolomics #NMR #GC-MS #LC-MS @mikelangelipid.bsky.social @crick.ac.uk

Fantastic study out today by superstar postdoc @aakritijain.bsky.social! It identifies the unresolved function of LyLAP, a protein associated with poor prognosis in PDAC. It is not a phospholipase but a membrane protein protease! Happy that I could help through our untargeted lipidomics platform

“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av

RIP any human subjects methods section: women, gender, female, excluded RIP math/stats: biases, marginalise, equality, inequality, group, inclusive RIP social sciences: status, systemic, political, group, socioeconomic, institutional, cultural This is not just evil it is also SO VERY DUMB

🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.

If you’re a federal govt employee targeted for leave or termination on the basis of your DEI work, please file an EEO (Equal Employment Opportunity) complaint & retain legal counsel. I’m a former NIH PI. Happy to refer you to a law firm that has successfully sued the govt many times! Pls repost 🙏❤️

Excited to share our new preprint! Exceptional work by @mikelangelipid.bsky.social identifies the first #LipidDroplet lipid quality control pathway! LD-localized FSP1 safeguards neutral lipids from peroxidation and prevents #ferroptosis. 🤩https://www.biorxiv.org/content/10.1101/2025.01.06.631537v1

I am excited to report the preprint of my postdoc work in the @olzmannlab.bsky.social! We have discovered the first lipid droplet quality control pathway with broad implications for lipid physiology and diseases associated with LD accumulation and oxidative stress! #lipidtime shorturl.at/2HqFd

Interested in #organelle biogenesis, subcellular #membrane #protein targeting or #LipidMetabolism? We are hiring! #PhD student or #postdoc. We combine #Biochemistry & #CellBiology with Computational Modeling & Experimental Physics / Physical Chemistry approaches. #research #academicsky #AcademicJob

Happy to see the scientific community thriving at Bluesky! I am a postdoc at UC Berkeley in the @olzmannlab.bsky.social and I combine lipidomics, redox and cell biology and in vitro biochemistry to understand pathways of cellular lipid quality control. Excited to see some cool #LipidTime on here!