Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...

Are you @ the late stages of your postdoc ? Want to pursue a PI career ? Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum www.helmholtz-munich.de/en/stem-cell... Peer-networking / Career orientation and more !!! Please distribute :) 🙂

The Argonautes 2025 - we made a special gift for participants - a card set with 32 different Argonautes + an extension pack with four Nobel prize winners from the small RNA field. Mello, Fire, Ambros & Ruvkun as jokers :-) #argonautes2025

Congratulations to Klaus Rajewsky, honored by EFIS with its first-ever Lifetime Achievement Award for his contributions to immunology. 🔗 www.mdc-berlin.de/news/news/kl...

Our paper using Oxford #Nanopore direct RNA sequencing to identify m6A modifications on RNA isoforms in human brain is now out in Science Advances. 🧪 www.science.org/doi/10.1126/...

every thing that's *not* in this picture is also science the education, training, sacrifice, opportunity, competition, failure, depression, defiance, resilience, confidence, curiosity, vision, passion and self-esteem to do it all over again

Hi everybody! I am super excited to share the work done during my PhD published in @nature today! We describe a new mechanism of self- vs. non-self RNA discrimination by showing how N-glycans shield glycoRNAs from stimulating endosomal RNA sensors www.nature.com/articles/s41...

If you like our recent work and are interested in developing a postdoc project related to isoform diversity in individual cell types and their regulation, get in contact! We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing

Identifying reproducible biomarkers for microbiome association studies requires sample sizes of thousands www.sciencedirect.com/science/arti...

Could a virus be behind the cause of Parkinson’s disease? New data on the 'pegivirus' has arrived. In a discovery that echoes the once-radical link between Helicobacter pylori and peptic ulcer disease, researchers have found human pegivirus in Parkinson’s disease. @parkinsondotorg.bsky.social

I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms www.nature.com/articles/s41...

1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler Tons of open slots, invited and selected speakers all get 20 mins ❤️ #EESNucleus

Kraus et al. report absolute miRNA concentrations required for productive cleavage of highly expressed transcripts and identify mouse miRNAs that reach this threshold in vivo bit.ly/44cYNvj

Just 3 months to go until the very first Warsaw GLIA Symposium! Expect top-notch speakers, cutting-edge science and an inspiring atmosphere. All the details + free registration (limited spots!) available here: sites.google.com/uw.edu.pl/wa... Let the countdown begin. #WGC leads the way! #GLIA

Ready to explore the world of phages through transcriptomics and advanced microscopy? Apply now to join our research team! @iimcb.bsky.social

RMBase v3.0: decode the landscape, mechanisms & functions of RNA modifications The Encyclopedia of RNA Epitranscriptome More than m6A "73 RNA modifications of 62 species" bioinformaticsscience.cn/rmbase/ @narjournal.bsky.social 2024 academic.oup.com/nar/article/...

European RNA scientists are some of the best. But when they launch their companies, they get 1/10th as much funding as their North American counterparts. My interview about this problem with Jean Schmitt from Jolt Capital and the EUVC team here: www.eu.vc/p/jean-schmi...

“What a [sunburned] cell is trying to do is make decisions about whether to live or die based on how damaged the DNA is… but amazingly, it’s the RNA that signals that. That’s the remarkable observation.” — Rachel Green, biologist at Johns Hopkins University. www.quantamagazine.org/rna-is-the-c...

Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...

Kyiv right now. This happens every time Trump talks to Putin and asks him to stop the war. If this is not the clearest answer Putin can send to Trump I don't know what is

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Manuscript/resource alert #microsky 🦠 My lab offers the community a collection of 30 E. coli (CloneFISH) cultures, each carrying a plasmid for the heterologous expression of a (near) full-length 16S rRNA gene from one of 30 lineages of archaea, including 19 yet uncultured ones.

#Argonautes2025 - argonautes.img.cas.cz Join us in Prague 27-30/8/2025 for the next edition of the Argonaute meeting #miRNA #siRNA #piRNA & #PIWI Abstract submission for talk selection deadline is 30/6! Please, spread the word @rnasociety.bsky.social @rti-umasschan.bsky.social

Horrible day in Kyiv today... Russians deliberately targeted a lot of apartment blocks, causing many fires, destruction, and casualties. Please continue supporting Ukraine, and donate to the air defense to prevent such tragedies e.g u24.gov.ua/sky-sentinel #UkrainianView

📣 Researchers in 🇵🇱Poland; ever considered applying for an ERC grant? In a webinar on 15 July you can ✅ Learn how to apply successfully ✅ Discover NCP support ✅ Get exclusive tips from an evaluator ✅ Hear testimonials from grant recipients Register 👉 bit.ly/ERC2025PL

Extracellular vesicles in the nervous system! With keynote @erikaholzbaur.bsky.social! So many great speakers and chairs, to name a few @rodallab.bsky.social @jasonsynaptic.bsky.social. Lots of slots for ECR talks. See you in Montreal! www.isev.org/2nd-isev-sym...

Vault RNAs aid RNA virus infection (Sindbis & encephalomyocarditis virus) by facilitating cytoplasmic localization of hnRNP C and ELAVL1 www.cell.com/cell-reports... @cp-cellreports.bsky.social

Neuronal aging leads to widespread dysregulation of RNA biology, including mislocalization of splicing proteins like TDP-43, chronic cellular stress, and reduced resiliency @kevinrhine.bsky.social www.nature.com/articles/s41...

#RNAsky #circRNA ...and more about DIS3... www.cell.com/cell-reports...

#spatialbiology #RNAbiology www.nature.com/articles/s41...

Premenstrual dysphoric disorder can cause monthly cycles of rage, depression, anxiety and self-harm. Treatments are limited, but new ideas about the condition could change that

🧫🔬 Are you a PhD student or a postdoc interested in RNA visualisation techniques? Last chance to apply for our 'FISHing for RNAs: classical to single molecule approaches' course – you have until 25 May! ✍🏼 #EMBOFISHingRNAs 👉🏻 https://s.embl.org/fis25-01-bl#EMBOFISHingRNAs 📅 31 Aug – 5 Sep 📍 EMBL Heidelberg

Every hear of Vaults? If not, read this preprint! New from the lab, exploring novel mechanisms of RNA trafficking in neurons and what they might mean for memory. Led by stellar PhD student Mason Musgrove. #RNAsky www.biorxiv.org/cgi/content/...

A 🧵 to walk those interested through this paper...

EMBO is #hiring a Scientific Editor (Absence cover) to join @emboreports.org. Apply by 8 June: buff.ly/seVUgYW 🧪

How political attacks could crush the mRNA vaccine revolution www.nature.com/articles/d41...

Are you a US-based academic that has prior ties to Sweden? Are you also 7-12 years from your PhD? If so, the Foundation for Strategic Research is providing funds of up to $1.5 mil (15m SEK) to bring you back to Sweden! Application deadline Sep 23. strategiska.se/pressmeddela...

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...

What human experimental models do we currently have to study brain disorders—and where do they fall short? In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.

Blood tests to diagnose schizophrenia: self-imposed limits in psychiatry (1) methodological problems ...a falsely presumed homogeneity of biological causes ... (2) professional fears... (3) conceptual problems, such as a dualistic mindset www.thelancet.com/journals/lan... via RG: shorturl.at/ZsYLu

New deadline 1st of June!

🚨I could not be more excited to share our new preprint on saturation genome editing of the small nuclear RNA (snRNA) RNU4-2: www.medrxiv.org/content/10.1... A super fun collaboration with incredible duo @gregfindlay.bsky.social @joachimdejonghe.bsky.social from @crick.ac.uk 🧬🖥️🩺 🧵1/12

Talk about impactful: ReNu syndrome linked to the RNU4-2 variation was discovered this time last year & now a global community has grown around those affected by the disease: www.renusyndrome.org/map

New lab paper out! 😀 We describe a new benchtop technique to isolate microRNAs from various cell types in a complex tissue (like the developing CNS). This is a fruitful collab with the Cremer lab from @ibdm.bsky.social journals.plos.org/plosgenetics... 1/n 🧵

Excited to share our latest work, published today in Nucleic Acids Research: "Mapping effective microRNA pairing beyond the seed using abasic modifications" - led by a former PhD student, now graduate of the lab, Dr David Kosek, in collaboration with Katja Petzold. 👉 doi.org/10.1093/nar/...

#ReThinkNeuroimmunology 3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology. Organized by @quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua Registrations 🔗 genelayinstitute.org/rtn/

The most complex disease in medicine is Parkinson's? YES. - Multiple organ systems. - Not a single disease. - A single biomarker or diagnostic test exists: no - Disease course is highly variable. - Complicated regimens. - Lot's of different symptoms, dopamine awakening, DBS and beyond.

The timeline of co-transcriptional #mRNA processing and #modification may have to be revised: cleavage, termination, and #m6A deposition may occur earlier than most #splicing! Potential textbook changing study in bioRxiv by edueyras.bsky.social & Rippei Hayashi labs! www.biorxiv.org/content/10.1...

Researchers at Karolinska Institute have identified a new mechanism where circular RNA plays a crucial role in wound healing, which could lead to new therapies to improve wound healing and reduce scarring. medicalxpress.com/news/2025-04...