Bioinformaticians / computational biologists take note - know where you should take your OS tool chain from and do not introduce backdoors.

🔹 What’s inside • Bulk, single-cell & single-nucleus RNA-seq from 8 lung-cancer cell lines spanning 3 cancer types for realistic DE analysis • Three long-read protocols (ONT PCR-cDNA, ONT direct RNA, PacBio Kinnex) and Illumina short-read sequencing • Synthetic spike-in controls for ground truth

Excited to share our latest preprint: LongBench—a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches. www.biorxiv.org/content/10.1...

Our paper using Oxford #Nanopore direct RNA sequencing to identify m6A modifications on RNA isoforms in human brain is now out in Science Advances. 🧪 www.science.org/doi/10.1126/...

The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. Learn more:

New pre-print from our wonderful collaborators at Roche, Genentech, and the University of Basel. A fun study investigating the molecular mechanisms of gymnosis (passive cellular uptake) of antisense oligonucleotides (ASOs). www.biorxiv.org/content/10.1...