#academia Hi! So question is When will I stop cleaning after my colleagues mess, fix their mistakes and re-do their job due to laziness in the #lab because I need that? not mentioning loss of time and effort which I have to spent for my work instead…

Jobin et al discover a second priming phase of CD8/DC interaction in the subfollicular LN area. CXCR3+ high-affinity CD8s can get IL-2 from "stop-and-go" moving CD4+ TCs, inducing affinity selection while Tregs mop up IL-2. in 🐭 @science.org 🧪⑂ 1/2 www.science.org/doi/10.1126/...

Cancel the poster session 🫠 #CanineSupport @theaacr.bsky.social #aacr2025

2025 Next Gen Star Awarded Dr. Anniina Färkkilä on todays’s Major symposium about spatial mapping of #Tumor ecosystem before/after neoadjuvant treatment to be used in favor of anti-tumor immunity in #ovariancancer (in the future, other cancers!) #aacr2025 @theaacr.bsky.social @afarkkila.bsky.social

Tonight at the #AACR2025 stage ! The Checkpoints! @patrickhwumd.bsky.social @jasonlukemd.bsky.social @theaacr.bsky.social

@johannajoyce.bsky.social giving a wonderful presentation about she and her team’s successful discoveries on immunosuppressive myeloid cell infiltration and their contribution to recurrence and progression of brain tumors and at the #aacr2025 Plenary Session

Great speech by the Head of Breast Cancer Group , Dr. Giampaolo Bianchini from San Raffaele Scientific Institute,Milan, Italy on early TNBC biomarker detection! #aacr2025 #breastcancer #tnbc #earlydetection

Can we track them back to the stemness in order to detect cancer in their “pre-cancerous” state? Dr. Ken Lau answers tese questions #Aacr2025 #cancer #detection #earlydetection

Hall run officially started! Put your running shoes #aacr2025 @

Ready for #AACR2025 This year, just 4 hours of driving : )

This review by @yibinkang.bsky.social et al. integrates key clinical, genetic, & pharmacologic data to suggest human disease settings where retinoic acid nuclear signaling plays a pathogenic role. rupress.org/jem/article/... 📘 In JEM #Cancer Collection rupress.org/jem/collecti... #AACR25

Surprisingly, some LEP gene mutations tied to obesity may reduce body weight by enhancing leptin function. A reminder that biology is rarely black and white. www.nature.com/articles/s42...

OMIP-114: A 36-Color Spectral Flow Cytometry Panel for Detailed Analysis of T Cell Activation and Regulation in Small Human Blood Volumes onlinelibrary.wiley.com/doi/full/10....

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease @nature.com www.nature.com/articles/s41...

🧠 Researchers created a single-cell atlas of brain metastases from various cancers, uncovering unique tumor-immune landscapes and microenvironmental niches. This comprehensive map offers insights for developing targeted treatments: www.cell.com/cancer-cell/... #CancerResearch #BrainMetastasis

CD8 T cell priming involves two phases: initial activation by dendritic cells, followed by a second phase where T cells re-cluster with DCs and receive IL-2 from CD4 T cells. This discovery could inform better immunotherapy strategies. www.science.org/doi/10.1126/... #Immunology #TCells

In #CancerCachexia, a brain-immune circuit in the area postrema links inflammation to apathy & low motivation. This explains how inflammation triggers loss of appetite & weight loss, pointing to possible new treatments. www.science.org/doi/10.1126/... #Neuroscience #Immunology

Last day of bioinformatics workshop of @itcrtraining.bsky.social at @umich.edu Very informative for who wants to fill the gap between the connections of informatics and wet lab !

Retroelement-specific tissue resident T cells control tissue resilience and predisposition to inflammation papers.ssrn.com/sol3/papers.... @belkaidlab.bsky.social

Blockade of ARG2 in TAMs leading to decreased pro-tumor cytokine expression (e.g., IL10, CD274, TGFB1), shifting macrophage polarization away from the pro-tumor phenotype. #TME #TNBC #immunology #breastcancer www.sciencedirect.com/science/arti...

One of the most comprehensive review I’ve seen after a long time about IL1b driven inflammation in TME !

Cool paper by the group of @msmelanoma.bsky.social in @naturecancer.bsky.social showing that tumor secreted growth factor midkine rewires DCs toward a tolerogenic state and promotes tumor immune escape. www.nature.com/articles/s43...

Findings from a Phase I trial suggest natural killer cells pre-complexed with AFM13 has promise for specific patients with lymphoma and may be adapted for more cancer types in the future. Learn more: brnw.ch/21wRN45 #EndCancer

Today we released our fourth article for @your.neighborhoodscientist.org! During this time when my future and the future of US science is uncertain, I’m finding a lot of comfort in my colleagues who continue to do beautiful work and Francesca’s words resonate deeply with me. Read & subscribe below:

Want to stay current with our members and affiliates? Check out the UVA immunology starter pack! If you're an immunologist at UVA and want to be added to the list, DM us! go.bsky.app/D6VcWYZ

CXCR3-mediated natural killer cell infiltration exacerbates white matter injury after intracerebral haemorrhage doi.org/10.1093/brai...

This is nozzle! Filter your samples! #flowcytometry #facts

New Heroes: @deisseroth.bsky.social has to be one of the most interesting scientists on the planet. Find out why: glass.photo/cm/6S9GiVGAH... @nationalacademies.org

In extremely premature infants, immune cell trajectories are distinct from those of full-term infants over the first 60 days of life www.science.org/doi/10.1126/...

For decades, we underestimated the importance of our lymphatic vessels to suppress cancer and its spread. Here's a new, open-access, outstanding review rupress.org/jem/article/...

holy shit, nerds 😍

IL-23 tunes inflammatory functions of human MAIT cells www.cell.com/iscience/ful... @laetitia-camard.bsky.social

30-Color Longitudinal Full-Spectrum Immunophenotyping and Sorting of Human Circulating Immune Cell Subsets Implicated in Systemic Autoimmune Rheumatic Diseases doi.org/10.1101/2025... @montserrat-anguera.bsky.social

"Our investigation into the effects of anti-CTLA-4 and anti-PD-1 on memory T cell formation in mice reveals that memory T cells generated by anti-CTLA-4 exhibit greater expansion, cytokine production, and antitumor activity than those from anti-PD-1." #Immunology #Immunotherapy

Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses www.cell.com/cell-reports... @cellreports.bsky.social

Are you looking for a #PhD position in the interdisciplinary field of #immunology #development #cellbiology? Do you love #macrophages? #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/ Pls repost👇 #immunosky

CD177 expressing neutrophils in Nucleus Accumbens regulating brain immune imbalance and stress-related behaviors www.sciencedirect.com/science/arti...

Why do certain genetic mutations impact leukocyte production or function? With Bone Marrow Organoids (BMOs), we can now explore this question in vitro! BMOs, derived from human iPSCs, provide a tool to study hematopoiesis. Yellow: nuclei Blue: mesenchymal cells #fluorescencefriday #ImmunoSky 🧪

The oestrous cycle stage affects mammary tumor sensitivity to chemotherapy www.nature.com/articles/s41... www.nature.com/articles/d41... www.nature.com/articles/d41...

✨This month - Human dendritic cells (DC)✨ using stable isotope labelling in healthy volunteers, we define the circulating lifespan of cDC subsets and explore their role in inflammation - huge thanks to the team and our amazing collaborators doi.org/10.1084/jem....

Are you a #postdoc with an innovative vision for starting your own lab in #Syntheticbiology, #Genomics, #GeneRegulation, #Development, #Cancer, #Immunology or #InfectionBiology? @IMPvienna is inviting applications for group leader positions: www.imp.ac.at/career/open-... Pls share!

Literally bleeding from flow.

Here is a list of online flow cytometry resources. Please feel free to add to the list! Online Communities: www.reddit.com/r/flowcytome... discord.gg/ySQFsz8gkB Podcasts: www.youtube.com/channel/UC_m... Blogs: www.colibri-cytometry.com Listserv: www.cyto.purdue.edu/content/cyto...

Check out our updated database of 189 PhD fellowships and funding opportunities. For each fellowship, we provide a description, $ amount, deadline, link to funder and eligibility criteria (such as citizenship). Good luck! Download freely here: research.jhu.edu/rdt/funding-...

Thanksgiving is the deadline for submission. Flood of flow data to analyze including 2018 data with 0 knowledge of which antibody is which color. Squeeze 3 abstract submission and 1 poster in 2 days. Dishwasher is broken, don’t know when be fixed. After 2 years,Mom’s here for 2 weeks only. Oopsz.

Cancer Immunology: bsky.app/starter-pack... A repertoire of immunologists II: bsky.app/starter-pack... Immunometabolism: bsky.app/starter-pack... Immunoengineering: bsky.app/starter-pack... A repertoire of immunologists: bsky.app/starter-pack...

Development of a Spectral Flow Cytometry Analysis Pipeline for High-Dimensional Immune Cell Characterization https://www.biorxiv.org/content/10.1101/2024.06.19.599633v1

Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...

This is AMAZING. newsroom.clevelandclinic.org/2024/11/08/c...