It was a pleasure to share the latest on next-gen cell therapies @ufhealthcancer.bsky.social today. Thank you for the opportunity to kick off your fall Grand Rounds. It’s always inspiring to connect with colleagues who share our drive to push the boundaries of discovery and care.

Had fun trying some new songs with @drdanarocks.bsky.social! What do you think of our take on the Chapell Roan megahit #PinkPonyClub? #MusicMonday #DocsWhoRock #TheReMissions

#ScienceSaturday 🧵 ❓ How can we target pancreatic cancer with T cells?

#ScienceSaturday 🧵 ❓ How does aging affect the immune cells infiltrating tumors? ➡️ As we age, our circulating blood and immune cells can develop mutations called clonal hematopoiesis of indeterminate potential (CHIP).

🗣️ Share this with the women in your life! The @NCCN has shared updated screening guidelines for women with extremely dense breasts. Moffitt’s Dr. Bethany Niell explains the new guidelines and why they are important. www.moffitt.org/endeavor/arc...

Excited to be joined by biotech executives, entrepreneurs, investors and researchers today at #MoffittBoB to discuss the latest advances in cancer care. A big thank you to Florida Secretary of Commerce Alex Kelly for kicking off the event at our leadership breakfast. @moffittnews.bsky.social

📢 New landmark research out today on #TILTherapy for GI cancers ❓Can neoantigen-specific tumor-infiltrating lymphocytes (TILs) improve #immunotherapy for gastrointestinal cancers?

Happy #NationalDoctorsDay! Join me in recognizing all of our inspiring docs who make a difference in the lives of our patients every day @moffittnews.bsky.social! Photos from our Doctors’ Day lunch celebration! 🩺🥼

#ScienceSaturday 🧵 ➡️ Melanoma secretes a protein called midkine (MDK), which plays a key role in reprogramming dendritic cells in the tumor microenvironment. ❓ How can this impact immune responses?

Thank you to Lakeland Commissioner Stephanie Madden and other Polk County leaders for joining us this week to tour our brand-new Moffitt at SouthShore ambulatory center!

Moffitt Cancer Center is proud to be the first standalone cancer center in the world to open a Nikon Center of Excellence! This prestigious achievement reflects our commitment to cutting-edge imaging technology and groundbreaking cancer research. Read more: bit.ly/41L1R0L

#ScienceSaturday 🧵 ❓ Are B cells important to eliminate cancers? T cells, capable of directly killing cancers, have been widely studied in tumor immunology.

#MusicMonday with my daughter Ally! Song: “I See the Light” from Tangled #tangled #rapunzel #fatherdaughter #duet #guitar #singing #harmonies #docswhorock

Moffitt’s #PetTherapy dogs, Kayba, CJ and Kayse are ready for a pawesome #Valentinesday2025! ❤️ 🐾 Thanks to @moffittnews.bsky.social volunteer Ken Price for bringing them to spread cheer among our patients and teams at Moffitt McKinley Outpatient Center!

Gratitude isn’t just important for the present, but the past and future, too. #ThursdayThoughts

#ScienceSaturday 🧵 🧬 Personalized cancer vaccines (PCV) train the immune system to recognize mutations unique to a patient's tumor, helping the body mount a targeted immune response. ❓ Can this approach help prevent renal cell carcinoma (RCC) from returning after surgery?

Join us in congratulating H. Lee Moffitt, the Outstanding Citizen of the Year, for his dedication to Tampa Bay and beyond! His vision led to a world-class cancer center, ensuring patients could receive top care in Florida. Read more: bit.ly/4aTbP4i #MoffittCancerCenter

Moffitt will be among a select group of elite U.S. cancer centers — and the only one in Tampa Bay — equipped with a next-generation, FDA-cleared, state-of-the-art proton therapy system. www.moffitt.org/newsroom/new...

On National Women Physicians Day, we celebrate the women at Moffitt who are transforming cancer care through advocacy, research and compassionate patient-centered care. Read more about their impact: bit.ly/413kBte #NWPD @jessicayislam.bsky.social

#ScienceSaturday 🧵 ➡️ Immunotherapies targeting neoantigens can be effective in mediating long-term durable responses in advanced cancer patients. However, identifying these neoantigens from metastatic tumors can be logistically challenging.

As leaders, we can shape the future of cancer care and research by mentoring the next generation! Lift others as you climb! #ThursdayThoughts

I am thrilled that @moffittnews.bsky.social has been named a Best and Brightest Company to Work For in the Nation once again! This honor reflects our incredible team and culture of excellence as we work together to contribute to the prevention and cure of cancer. www.moffitt.org/newsroom/new...

Happy #MusicMonday! #TheReMissions had so much fun covering “All of Me” by the legendary Billie Holiday. Music has a way of bringing us together and lifting spirits. Hope this brightens your day! @drdanarocks.bsky.social #DocsWhoRock

Do you know what a biorepository is? 🧊❄️ @moffittnews.bsky.social, we're bringing deep-freeze technology to the Sunshine State to advance cancer research and care. Read more to see how this cutting-edge facility will help save lives: www.moffitt.org/endeavor/arc...

#ScienceSaturday 🧵 ❓ What is the "obesity paradox" in cancer #immunotherapy? ➡️ Although obesity increases the risk of #cancer, it's also been linked with better outcomes for some patients treated with immune checkpoint inhibitors (ICIs), a type of immunotherapy.

We are so thrilled to begin serving patients at Moffitt at SouthShore in just a few short days. Learn more about the newest @moffittnews.bsky.social facility in this piece from ABC Action News! www.abcactionnews.com/news/region-...

So great to connect with fellows from our Urologic Oncology, BMT, Gynecologic Oncology and Pathology teams @moffittnews.bsky.social at a recent breakfast with Dr. Karen Lu and Dr. John Cleveland! Thank you for your important role in shaping the future of oncology!

Enjoyed having the Stanley Cup visit Moffitt Cancer Center today! 🏆

Acts of injustice—from discrimination to genocide—are only made possible when we allow dehumanization & hate into our hearts and communities. We All is a song about love & seeing ourselves in the “other”. Hate cannot drive out hate. Only love can do that. #MLK #MusicMonday

#ScienceSaturday 🧵 ➡️ T cells recognize tumors through binding of their T-cell receptors (TCRs) to peptide antigens within MHC molecules. ❓ What is the optimal strength of this receptor binding, known as “avidity”, to mediate antitumor immunity?

While at the 43rd Annual J.P. Morgan Healthcare Conference, Moffitt and @Cryoportinc leaders celebrated a major milestone. Cryoport’s CRYOGENE will provide Moffitt's #SperosFL with state-of-the-art biorepository services. Read more about this strategic partnership: bit.ly/40yKMaG #JPM25 #JPMHC25

Running a cancer center requires a massive team effort, where every decision, discovery and patient interaction contributes to the big picture. #ThursdayThoughts

Diagnosed with stage 4 metastatic breast cancer just a week after giving birth, Dallas Carroll faced an uncertain future. But an experimental vaccine gives her a shot at a cure. Discover how cutting-edge treatments like dendritic cell vaccines are transforming lives. #CancerResearch

Honored to speak today at the Hillsborough County Board of County Commissioners meeting, where we had a great conversation about advancing #cancer care across Tampa Bay and beyond. Excited to highlight the opening of our newest outpatient center, Moffitt at SouthShore! @moffittnews.bsky.social

Enjoyed listening to special guest Dr. Tullia Bruno speak on the role of B cells in tumor immunity today @moffittnews.bsky.social. Great talk! Thank you for joining us for our #Immunology seminar series.

As a tribute to former president Jimmy Carter, #TheReMissions covered "Georgia on My Mind." Carter's successful treatment for metastatic #melanoma brought immunotherapy into the limelight, inspired hope for countless patients, and reminds us of the power of #CancerResearch! #MusicMonday

Cheering on the @tampabaybuccaneers.bsky.social! #GoBucs #WeAreTheKrewe

(1/3) #ScienceSaturday ➡️ How does the history of T cells impact their ability to fight #cancer when engineered with chimeric antigen receptors?

The ribbon has been cut! We are eager to welcome patients at #MoffittSouthShore beginning January 27th, 2025.

Moffitt at SouthShore Feb. 2024 ➡️ Jan. 2025. Watch our Grand Opening live on YouTube at bit.ly/3DT0t3S @moffittnews.bsky.social

Cancer care and research is an ever-evolving field, and our work reminds us that truly impactful progress can often be made by forging new paths. #ThursdayThoughts

This summer, Moffitt McKinley Hospital celebrated its first year of serving patients. Team members have embraced the Moffitt culture, offering smiles, support and care to all. Discover their impactful moments from the past year. 👇

About 1/3 of all cancers diagnosed annually can be prevented, and more can be cured by early detection through screening. Do you know what #cancer screenings you should get? Check out the recommended screenings and prioritize your health this New Year! www.moffitt.org/endeavor/arc...

Nothing like recreating a classic in your own unique style. Loved doing this cover of “Somewhere Over the Rainbow” with @drdanarocks.bsky.social and #MarkRobertsonTessi! #MusicMonday #TheReMissions #DocsWhoRock

#ScienceSaturday #CancerVaccines are being intensively studied and may one day become an important modality to treat cancer and prevent recurrence.

We are all the authors of our own story. What will you write in yours this year? #ThursdayThoughts

Reflecting on the groundbreaking research of 2024 @moffittnews.bsky.social ! From innovative treatments to breakthrough discoveries, we continue to push boundaries in cancer care. 🔗 Read more here: www.moffitt.org/endeavor/arc... Excited for what’s to come in 2025. 🎉

(1/3) #ScienceSaturday Treating #neurological disorders like #brain tumors is difficult in part due to a protective “wall” called the blood-brain barrier, meant to block toxins from reaching brain cells.

#ScienceSaturday HER2-positive #BreastCancer is notoriously aggressive and difficult to treat. A study led by Dr. Brian Czernicki involved injecting immune-boosting dendritic cells directly into tumors in combination with targeted therapies before chemotherapy.

#ScienceSaturday CD28 is an important costimulatory molecule for T cells. However, in a recent study, Yang et al utilized a whole genome CRISPR screen in a breast cancer model to identify that tumors can also use CD28 signaling to inhibit T cells through upregulation of PDL1 on the tumor surface.