Dagan Segal (@dagansegal.bsky.social)

The Balbiani body is formed by microtubule-controlled molecular condensation of Buc in early oogenesis Kar et al. demonstrate that Balbiani body (Bb) formation is achieved via developmental condensation in zebrafish oogenesis, driven by Buc phase separation and evolving from a dynamic liquid-like state into a solid-like stable compartment. Multistep regulation by microtubules controls condensation, ensuring proper Bb formation and oocyte polarity. https://cell.com/current-biology/fulltext/S0960-9822(24)01623-3