1/9 Thrilled to share that our paper, “Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm,” is now published in @cp-cellreports.bsky.social! @amatrudalab.bsky.social @crumplab.bsky.social www.cell.com/cell-reports...

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence: Cell Reports www.cell.com/cell-reports... Latest from @hatleylab.bsky.social

A first-in-human study of universal donor CAR NK cells for acute myeloid leukemia could pave a path for a new approach to treating cancer. #NKCells #CancerResearch #PedSky #AML https://bit.ly/47RkgO4

Zebrafish people! The @ZDMSociety annual meeting is in Boston this year, with a great lineup. Abstract submission is closing May 27th. Go register now for this always fun conference #zebrafish www.zdmsociety.org/zdm18-home

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2

We are recruiting a tenure-track Assistant Professor in the Center for Childhood #Cancer Research. Come work with me! More information 👇

Very proud of our partner papers in @cp-cellreports.bsky.social and @cp-cellrepmethods.bsky.social from collaborative work in my lab and Benjamin Stanton's lab focused on fusion-positive #rhabdomyosarcoma. #TeamFishAndChIPs

🚨🚨🚨 Tol2kit announcement! We have rebuilt the wiki that was corrupted a few months ago! We’re in the process of also linking it to the original address. Please visit us here: tol2kitkwan.genetics.utah.edu Thank you for your patience!! #zebrafish #transgenesis #plasmids #sharing

Our study, led by Dr. Patricia Tiburcio, showed that blocking protein recycling may help fight anaplastic Wilms Tumor—a rare, aggressive childhood kidney cancer. Combining bortezomib with dactinomycin made tumors more sensitive to treatment in the lab. doi.org/10.1016/j.xc...

We are excited to announce the winner of the George Streisinger Award, the 2025 MBL Course Directors! The Streisinger Award will be presented to them at the 19th IZFC in Madison, WI, where they will also present the Award Lecture. Congratulations to all of them!

Abstract deadline for #ZDM18 in Boston ends tonight (EST) for those to be considered for oral talks. More details here: www.zdmsociety.org/zdm18-abstra... #ZebrafishMeeting

Zebrafish + behavior? You come to the right place! Join us for the ZDMS webinar on Wednesday, June 4th at 10AM ET. Four incredible speakers will be sharing their expertise! Sign up here 👇 www.zdmsociety.org/2025-zdms-ri... #zebrafish #neuroscience

To dissect the gene regulatory networks used to build organisms, we need Perturb-seq-like tools that work in whole animals. For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq. www.biorxiv.org/content/10.1...

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

Free Webinar - Cancer research using zebrafish models, #ZDMS 2025 Cancer RIG Meet-up on Wednesday 28 May (10-11.30AM EST) exciting stories by rising stars of zebrafish cancer research field us06web.zoom.us/meeting/regi....

Attention ZDMS Members and greater fish community: A message from the Local Organizing Committee for #ZDM18! The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)

This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...

The Kendall Lab is at #AACR25! Jack Kucinski is presenting in the Developmental Origins and Drivers of Pediatric Cancers poster session on Monday afternoon. Chinmay Sankhe and Delia Calderon are presenting at the Pediatric Cancer Models poster session on Tuesday morning. Hope to see you there!

I really enjoyed my conversation with Rita Fior for our inaugural feature on zebrafish in translational research!

Just finished up the materials for a intro to R workshop I'm running for folks at work. Thought I would post the GitHub to the materials here as well in case it was of use to anyone else: github.com/MVesuviusC/R... 🧬 🖥️ #bioinformatics #genomics #tidyverse #R #rstats #programming #r4ds

This issue of #GENETICS offers updates on 6 model organism databases & knowledgebases: buff.ly/Mn0hIzl 🔎 AgBioData Consortium 🔎 Candida Genome Database 🔎 Saccharomyces Genome Database 🔎 SpudDB 🔎 Unified Phenotype Ontology 🔎 Zebrafish Information Network Remember to cite your community resources!

Now @michaelhoffman.bsky.social starting his talk on inferring transcription factor binding from different data modalities. Loved the reference to Cunningham’s law #AACRprecmed25

Now: @alice.soragnilab.com: Patient-derived tumor organoid models to identify drug susceptibilities in rare cancers #AACRprecmed25 🧪🧬🖥️

This first AACR meeting on functional and genomic precision medicine has officially started! Dr. Mardis gave the introductory remarks followed by our first plenary speaker, Dr. Flaherty, who will focus on the collision of genomic and functional precision medicine #AACRPM25

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. https://go.nature.com/41a7Zzj

Special shout out this AM to NIH 🧪 grant mgmt specialists, POs, and SROs during this chaotic time - THANK YOU for caring for our grants and uploading scores/summary statements despite the unprecedented challenges you may be facing. You are science warriors and we APPRECIATE & SUPPORT YOU 🫶

I am deeply grateful to the extremely hard-working and dedicated staff at the NIH and NSF. Thank you to all of the Program Officers, Scientific Review Officers, Grants Management Specialists, and so many more, who have made the engine of US science and innovation run.

Switching fields to #zebrafish? Wanting to become an expert in zebrafish research? Check-out the @mblscience.bsky.social 2025 Zebrafish Development & Genetics course – a fantastic opportunity to learn from leaders in the field! Application deadline: March 13 www.mbl.edu/education/ad...

Celebrate 'International Day of Women and Girls in Science Day' by strengthening your timeline with these outstanding Scientists! *Now in two volumes below* 🧪 #WomenInScience (Volume 1): go.bsky.app/4BegEjv #WomenInScience (Volume 2): go.bsky.app/VoebYrt

[Meeting] Lorentz Workshop: Zebrafish Against Cancer – Towards Clinical Relevance, June 3 - 6, 2025, Universiteit Leiden, Netherlands zfin.atlassian.net/wiki/spaces/...

We are so excited to return to Madison, WI for the first time since 2018 for the 19th IZFC! We hope to see you all there! Be sure to lock in the early bird rate by registering today: www.izfs.org/education/19...

Preprint Alert📣 Our work ✳️uncovers a distinct cancer cell state with survival advantages in the pediatric cancer *Ewing Sarcoma* ✳️implicates membrane invaginations called *caveolae* that drive survival through subcellular organization of signaling molecules on the cell surface. Check it out! 👇

Hi - I am very sorry for the disruption. The website got corrupted over the holidays and we don’t know why. My IT people are working on it, and I hope to have the website back up before too long. In the meantime, please email me ([email protected]) and I will send you info and sequences.

Why haven't childhood cancers respond to immune checkpoint inhibitors (ICIs) like adult cancers? New preprint from the lab! PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor www.biorxiv.org/content/10.1...

The Burger lab is officially open! We hire on all levels, please feel free to contact me here about job opportunities.

IZFS Webinar Tomorrow: Studying Hematopoiesis & Solid Tumors in Zebrafish. Presented by Joey Ghersi, PhD and Madeline Hayes, PhD at 2:00pm EST. IZFS Webinars are FREE to members, and only $25 to non-members. Register here today! izfs.execinc.com/edibo/Webinars

Highlights fascinating new work coming from the lab of Dr. Rita Fior at Fundação Champalimaud 👩‍🔬🐟

Excited this is out now! Lots of hard work from Cenny and Yuan 👩‍💻👩‍💻 to make it rigorous, useful, and user friendly. We use it all the time and hope you like it too! And of course it’s #zebrafish friendly.