With @burgesslab.bsky.social, not one, but TWO freshly caught T2T zebrafish reference genomes for the Tübingen and AB strains 🎣 🎣 🎉

#DBfeature 🐠 A new powerful live imaging platform tracks Erk signalling dynamics in developing zebrafish hepatocytes at single-cell resolution. By Faraz Ahmed Butt, Alessandro De Simone, Stefano Di Talia, Kenneth Poss tinyurl.com/ve5vzp6c

For those interested, we’ve got two #WomenInScience lists, a list of resource and society accounts that support #zebrafish and lists of Senior Scientists & Group Leaders that work with our favorite fish. If you’re not on a list and want to be added (or just want to double-check), please reach out! 🧪

However long I live here I will never get used to how utterly beautiful the views from Princes St are. This was last night 😍

Inject some #zebrafish into your timeline with our updated Starter Packs! 🧪 WomenInScience v1: go.bsky.app/4BegEjv "" v2: go.bsky.app/VoebYrt Resources: go.bsky.app/JcC5df3 Sr. Scientists & PIs v1: go.bsky.app/2cHYybY "" v2: go.bsky.app/4zBuxAF "" v3: go.bsky.app/JvjuSZg "" v4: go.bsky.app/2c4WLQK

The first international workshop that focused on #zebrafish was convened in 1990 in Eugene, Oregon. Sponsored by NIH and NSF, the gathering of ∼40 scientists sought to evaluate the research potential of the tiny fish. Today, nearly 1,800+ zebrafish labs exist worldwide. #ZebrafishFunFacts 🧪

Hot off the press, after years of work by many PG and undergrads and collaborators, we present you wilth a detailed analysis of oncogenic RAS driven cellular plasticity and host immune response within 24 hours of oncogene activation in a #zebrafish model www.cell.com/cell-reports...

The @fengfishlab.bsky.social lab have found that mutation in the Ras gene can change normal cells and trigger an immune response that promotes cancer formation - all within 24 hours. This may offer new ways to detect or prevent cancer before it becomes established. edin.ac/47h6bZq

Wondered what my daughter was up to during half-term? She presented these carefully crafted B-day gifts to me this morning! 😊😊

Chinese national interested in a PhD using fish? Fully-funded scholarships @bristolbiosci.bsky.social from the China Scholarship Council-University of Bristol Success rates are high, check out the details here and get in touch: www.bristol.ac.uk/students/sup... Please circulate widely!

Anyone still using these? We should be able to do an update, if there’s interest. #zebrafish

Timely and important👇zebrafish cancer models provide unprecedented mechanistic insights on immune-cancer interaction 👏👏👏 solid work takes years to mature!!!

Zebrafish embryo undergoing gastrulation. Credit to Dr. Gopi Shah at EMBL. #ZebrafishZunday 🧪

Today we are honoured to host Dr Sally Lowell @cellysally.bsky.social (University of Edinburgh), winner of the 2024 BSDB Wolpert Medal, who is giving a talk in our DRN external seminar series @bsdb.bsky.social Host: Marysia Placzek All welcome!

1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

Twittering Machine, Paul Klee, 1922, gouache, ink and watercolor on paper

A short thread. For years, I have been surprised by how much confusion our discovery of clones carrying cancer-driver mutations in normal tissues has caused in the cancer community. Typical questions like: (1) if you see these mutations in normal cells, are they really cancer drivers?... [1/4]

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

Just out in @science.org: Together with the lab of @johanneszuber.bsky.social, we used sequential in-vitro/in-vivo screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...

Meet the 2025 cohort of @dev-journal.bsky.social Pathway to Independence fellows Read about the scientific visions of eight dev bio post-docs entering the academic job market journals.biologists.com/dev/article/...

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...

Transitions in development – an interview with Jeffrey Farrell @jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches. journals.biologists.com/dev/article/...

Hey friends - Daniocell is experiencing a temporary outage right now. The NICHD server it is hosted on got dropped from the NIH’s firewall list & so currently can’t be accessed outside the NIH. The relevant IT teams are working to resolve it. Sorry for any inconvenience. It’ll be back soon!!

#IZFC2025 #zebrafish #DANIO-CODE data coordination centre is back online. Note changed address: danio-code-dcc.genereg.net

Wrote a big review with my friend and colleague @varshneylab.social on the state-of-the-art in CRISPR used experimentally in vivo. We wanted to focus on their use in experimental vertebrate animals (apparently passé now but we persist).

Speaker update for our Generative Biology workshop: we are delighted to have @nmoris.bsky.social join us. See full list of speakers on the attached flyer or on our website. Apply by 15th August. Places available for short talks. royalsociety.org/science-even...

Respiratory infections reactivate dormant metastatic breast cancer cells in mouse lungs, correlating with evidence in humans that #SARS-CoV-2 infection increases the risk of cancer-related mortality & lung metastasis 😎 biology but double whammy for cancer patients www.nature.com/articles/s41... 🧪

This is why we love #cellmigration #Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis. I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock ! #scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬

Please RT: Published today, a super fun collaboration w/ @fanjumeng.bsky.social and Marnie Halpern's lab to establish methods for transgene mapping in zebrafish - TransTag enables simple and efficient transgene mapping in zebrafish via tagmentation: Cell Reports Methods www.cell.com/cell-reports...

New study online today! We present a method to identify insertion sites of Tol2 transgenes in zebrafish #zebrafish #Tol2 #Transgene www.cell.com/cell-reports...

Abstract deadline for #ZDM18 in Boston ends tonight (EST) for those to be considered for oral talks. More details here: www.zdmsociety.org/zdm18-abstra... #ZebrafishMeeting

Now online in Cancer Discovery: Detection of Cancers Three Years Prior to Diagnosis Using Plasma Cell-Free DNA - by Yuxuan Wang, Nickolas Papadopoulos, Elizabeth Platz, Bert Vogelstein, and colleagues doi.org/10.1158/2159...

This happens tomorrow, still time to register, free webinar, cutting edge zebrafish cancer model stories! Come join us!

There’s now a MedakaBase paper that you can cite, courtesy of @kurakulabmsm.bsky.social 🐠 🔗 to MedakaBase: medakabase.nbrp.jp

Check out the latest microscopy preprints including our recent favorite tool (LUCID) from #WeinsteinLab 🔥 🔗 to preprint: www.biorxiv.org/content/10.1...

Some exciting news! NCBI has finished the annotation pipeline for our new #zebrafish reference sequence GRCz12tu: www.ncbi.nlm.nih.gov/refseq/annot... This is a big step up in data depth and quality and should be super helpful going forward.

#ZebrafishMeeting, for those interested!

Free Webinar - Cancer research using zebrafish models, #ZDMS 2025 Cancer RIG Meet-up on Wednesday 28 May (10-11.30AM EST) exciting stories by rising stars of zebrafish cancer research field us06web.zoom.us/meeting/regi....

In this very cool 1-2 punch from the Weinstein lab, start by reading Miranda & co’s awesome pre-print about a novel epigenetic reporter and follow it up with @jimmykjm.bsky.social’s pre-print using it to characterize epigenetic reprogramming during fin regeneration: www.biorxiv.org/content/10.1...

@zebrafish007.bsky.social, @zebrafishmk.bsky.social et al. #WeinsteinLab describe a previously uncharacterized external, experimentally accessible secondary lymphoid organ in the #zebrafish located above the pectoral fin. rupress.org/jem/article/...

It has been a while since I advertised some of the tools we have released to help researchers analyze the zebrafish genome. So a brief Bluetorial on our zebrafish genomics UCSC public data hub and the bigger effort led by @ferencmueller.bsky.social to create a zebrafish ENCODE project (Danio-CODE):

Our search for a flow cytometry core facility manager for King's Buildings, University of Edinburgh, is finally live. Join us! Conventional & spectral. Parasites, immune cells, algae, bacteria, yeast and more. Full-time, open-ended. Apply by 17 March. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

We're looking for a new Reviews Editor for Development. Come and work with our fantastic team of in-house staff and academic editors and help to shape the reviews content of the journal. Feel free to get in touch informally if you want to find out more about the role.

The @uantwerpen.be Lab for Cell Biology & Histology (CBH; www.uantwerpen.be/en/rg/celw/) has an opening for a PI position in neuro-immune signalling. CBH is active in a variety of research areas such as aging, neurodegeneration and the gut-brain axis. www.uantwerpen.be/nl/jobs/vaca...

Spots still available for the Cancer epigenetics meeting hosted by @ludwigcancer.bsky.social at Oxford @ox.ac.uk. Amazing lineup of speakers including Craig Thompson, Scott Lowe, Caroline Bartman and many others. Info here - register soon!: ludwigoxfordepicancer2025.my.canva.site

Hot from the press: #CellMigration #vesicles #organelles Jeppesen et al @mag2art.bsky.social lab introduce blebbisomes: organelle-rich motile vesicles, have immune checkpoint inhibitors, released by #cancer cells & used for #cellcomm @naturecellbiology.bsky.social www.nature.com/articles/s41... 🧪🔬

We must all support and applaude PLOS for adhering to their core principles.

#DanioDigest (November/December/January – 2024/2025) Zebrafish Rock! celebrates its 7th anniversary since its relaunch! Dr Sonya Neal @neal-lab.bsky.social#DanioDigestreceives US Presidential Early Career Award for Scientists and Engineers. (1/42)

Joint us at the BRS 2025 in Edinburgh. It's time to submit your abstract for BRS 2025! The deadline is Monday 3 March 2025 (23:59 GMT)