@biorxivpreprint.bsky.social A single-cell atlas of intestinal immune cells across the day-night cycle reveals dynamic populations www.biorxiv.org/content/10.6... @jkpfeiff.bsky.social @utswim.bsky.social @lhooperlab.bsky.social

Review @natrevimmunol.nature.com How crosstalk at the immune synapse shapes T cell and dendritic cell biologys www.nature.com/articles/s41...

New tech adventure: co-founded Newton Biotwins together with @mirobueno.bsky.social. We're building #DigitalTwins for the lab — starting with a flow cytometry twin. Turning #biology into an information science! newtonbiotwins.com/en/home_en/

Preprint out! By controlling growth, via RNAP, we control the entire cellular machinery, and tune the cellular context into distinct, stable states. See how NOT gates behave! Kudos to @angeles-hg.bsky.social and @mirobueno.bsky.social 🔗https://www.biorxiv.org/content/10.64898/2025.12.19.695408v1

Grateful for the invitation to present at the 3rd Research Day of the METRI²A Group at @idibaps.bsky.social. A pleasure to discuss how #microbial metabolism of allergens impacts #allergicinflammation and #anaphylaxis.

Researchers in #ScienceTranslationalMedicine find a distinct #Bcell and antibody profile in infants and mothers in an Older Order Mennonite farming community, associated with lower incidence of egg #allergy. https://scim.ag/48rPBGS

We enjoyed discussing in @allergy-eaaci.bsky.social the findings by Cembellin-Prieto et al. (@johnshopkinsmmi.bsky.social) published in @natimmunol.nature.com, who identified a regulatory #mechanism mediated by #Bcell-derived #acetylcholine during #influenza #infection. doi.org/10.1111/all....

CompITO study compares rush vs. conventional oral immunotherapy for milk and egg allergy management—find out more! #FoodAllergy #Immunotherapy #CompITO doi.org/10.1111/cea....

“The bad review will come from your list of suggested reviewers”

Enzymatic and autophagic catabolism of lipid droplets after unsaturated fatty acid uptake induces pathogenic TH2 cells @sciimmunology.bsky.social www.science.org/doi/10.1126/...

Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research go.nature.com/4hriohE

We #run for #science & type 2 #immunity in #Madrid! #YoCorroPorLaCiencia @csic.es

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

SMI Member Eduardo Villablanca and colleagues review B cells in inflammatory bowel disease at Immunology Letters: www.sciencedirect.com/science/arti... #SMIMemberPaper #MucosalImmunology #Immunology

I’m excited to share a perspective that an incredible group of experts in the B cell field worked on over the past 2 years. The thoughtful conversations resulted in what we hope will be a helpful framework moving forward. An open access link is available below: urldefense.com/v3/__https:/...

Celia & Elisa participated at #SICAM at isciiisalud.bsky.social. Contrats to Elisa for winning the Best Oral Talk Award (sponsored by Inmunotek) on #Microbial #metabolism of food #allergens drives #IgE-mediated #anaphylaxis. A collaboration with the Caminero Lab at @mcmasteruniversity.bsky.social

"The day the paper was published should have been a moment of pride. Instead, it felt like a quiet erasure." #ScienceWorkingLife https://scim.ag/4p3eH5g

With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.

👏Congratulations to Prof. Klaus Rajewsky on receiving the first ever #EFIS Lifetime Achievement Award which recognizes not only his groundbreaking science but also his mentorship of countless young researchers worldwide. We honor his vision, brilliance + generosity.Thank you for inspiring us all.

In Seminars in #Immunology, we comment how #microbes may be central to the developmemt and progression of #food #allergy and #celiac disease, and their therapeutic implications. doi.org/10.1016/j.sm...

Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens @science.org Comment: www.science.org/doi/10.1126/... on @rmedzhitov.bsky.social @stephanieeisen.bsky.social www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

Thanks to P’ng Loke and Oyebola Oyesola for highlighting our recent article on immune-stromal interactions in @cp-trendsparasitol.bsky.social!! IFNg does it all!! www.cell.com/trends/paras...

Take a look at our feedback 👉👈 www.preprintclub.com/preprint-rev...

Predatory practices—journals, meetings etc—are spoiling the research landscape and erasing trust in science. But what can be done? Here Timmis et al inspect the phenomenon & propose a few measures to contain and even revert the damage enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

Online now: Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

Today #preprinthub2’s @alisaiakupova.bsky.social will lead a discussion of this #preprint 🥜🐭🦠

ICYMI by First release - now in print @science.org Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection. buff.ly/3DjNQ1e By @cicacanesso.bsky.social @danmucida.bsky.social @victora.bsky.social et al

Our article "Allergic #inflammation triggers #dyslipidemia via IgG signalling" published in Allergy received the award for "Best Scientific Publication of Young Researchers 2024" at the Princess Hospital Excellent Awards". doi.org/10.1111/all....

In this @biorxivpreprint.bsky.social @biorxiv-immuno.bsky.social, we show that #oral #bacteria can break down #food #allergens, potentially affecting their systemic absorption, #IgE recognition, and allergic reactions—including #anaphylaxis. www.biorxiv.org/content/10.1...

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis https://www.biorxiv.org/content/10.1101/2025.02.17.638013v1

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis https://www.biorxiv.org/content/10.1101/2025.02.17.638013v1

Anaphylaxis: Spotlight on Inflammation - Editorial in Clinical & Experimental Allergy (Jan 2025 Issue) – By Emilio Nuñez, Mattia Giovannini et.al. doi.org/10.1111/cea....

Microbiota translocation following intestinal barrier disruption promotes Mincle-mediated training of myeloid progenitors in the bone marrow @cp-immunity.bsky.social @sancholab.bsky.social www.cell.com/immunity/ful...

Diacylglycerol kinase zeta dictates CD40-mediated immune synapse formation, mTORC1 signaling and plasma cell fate in B lymphocytes https://www.biorxiv.org/content/10.1101/2025.01.11.632541v1

In this new study, published in Allergy, we show that #IgE can form without first switching through #IgG1. The IgG1 step had minimal impact on allergic response or long-term memory. #Immunology #Allergy #Therapeutics #Anaphylaxis 📄 Full article: doi.org/10.1111/all....

Using a food allergy model in mice incapable of class switch recombination to IgG1, the Jordana-Waserman Lab showed that sequential class switching is redundant for the production of anaphylactic IgE and allergic recall responses. onlinelibrary.wiley.com/doi/10.1111/... #immunology #Immunosky

The role of #inflammation has been underlined as central in several atopic #diseases, but, surprisingly, not in #anaphylaxis. doi.org/10.1111/cea....

What is the effect of increased bacterial dissemination in distant organs? Check our www.biorxiv.org/content/10.1... 1 Gut barrier disruption induces trained immunity in bone marrow progenitors 2 Enterococcus faecalis translocates to the bone marrow inducing trained immunity

Fascinating new paper about how commensal #fungi can promote #type2 responses in mice, a process involving fungal induction of #IL-33 🍄 🧪 #ImmunoSky www.nature.com/articles/s41...

Happy to share our latest paper on T follicular helper cell profiles that distinguish milk allergy from eosinophilic esophagitis

Congratulations to Dr. Emilio Nuñez-Borque on delivering an invited talk at #SEAIC2024 about #extracellular #vesicles and #microRNAs in #anaphylaxis!

Very excited to share the most recent work from #theonlylabever out in @jexpmed.bsky.social We show that a gut protozoan commensal acts as a natural adjuvant for IgA against oral and bacterial antigens to strengthen homeostasis. Hope you will find this interesting: doi.org/10.1084/jem....