We must have been #ExtraNice this year- our #cilia & #centrosome 🧪 community- 🎅 Santa just dropped the 1st session of 2026 line-up @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposia- www.eventbrite.co.uk/e/bscb-genso... See you on the other side! Happy Holidays!

Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Congratulations Dr. Fariña-Mosquera!!! A new doctor in the @luderslab.bsky.social!!! Big thanks to tribunal members Isabelle Vernos, Virginie Hamel @centriolelab.bsky.social , and Fernando Romero-Balestra!

Happy Halloween everyone! 🎃

Congratulations to the @estebanezlab.bsky.social lab and collaborators!!! A great story on the surprising repertoire of nuclear receptor oligomeric configurations and their regulatory roles.

Why would anyone want to be a scientist? url: journals.biologists.com/jcs/article/...

FINALLY! Challenging to publish but we believe it is an important discovery: rdcu.be/eATFz 💚 Thanks to the team ‪@biswashere.bsky.social‬, Omar Muñoz, ✨Q✨ C. Hoege, B. Lorton, R. Nikolay ‪@matthewkraushar.bsky.social‬ @dshechter.bsky.social @gucklab.bsky.social @vasilyzaburdaev.bsky.social‬ 💚

See? There's money! What would be great, instead, is to increase the budget for the existing schemes, though 🧪

"Super level" funding programs IMO are a huge waste of money - they benefit big labs at the cost of defunding others. We had big "Foundation grants" in Canada (albeit at a much smaller scale than similar programs in the USA/EU)... TL;DR it nearly ruined the sustainability of our research ecosystem

The #ESEB2025 meeting in Barcelona is getting closer, there are still places available but time for registration is running up. Are you going to miss the main evolutionary biology event in Europe this year? 👇 eseb2025.com/registration/

Woah! Sick reconstitution work showing that MAP6d1 recruits tubulin to form B tubules on A tubule templates, and ALSO intra-luminal protofilaments, which apparently are present in neuronal microtubules. So not only actin inside microtubules, but also additional tubulin protofilaments?!? Wild!

Check out this new 🔥work from Bryan Tsou’s lab - where does the information on how to assemble #centrioles with specific symmetry come from? Forget what you thought you knew about #centriole #biogenesis!!! www.biorxiv.org/content/10.1...

It is alive!!! Prompt to Google’s Vids AI video generation tool: “Show #microtubule #nucleation from gamma-tubulin ring complexes with microtubules displaying dynamic instability.”

A new AI video generation tool popped up in my Google workspace today - this did not go so well 😂 I gave it this prompt: “Show the #centriole duplication cycle with animated centrioles and their behavior during the #cell cycle. Use a simple, clean, cartoonish style.”

Great news not only for the #CRG but also for the wider Barcelona cell biology research community! And of course also for all #centrosome and #cilia aficionados!

Planning killer experiments during evening ride with view

#UExM Tetris by @luderslab.bsky.social members Marcos Fariña and Júlia Mestres reveals highly abnormal #centriole configurations 👀

During #mitosis, before assembling the mitotic spindle, the early mouse embryo lacking #centrosomes uses #actin rather than #microtubules for chromosome congression 👀👇🏼

This is big - the effect of cancer mutations on HSCs is determined by pre-existing properties of the stem cell affected! Crazy results on NPM1 🤩

Insightful work from the Raff lab on how to build mitotic centrosomes (including artificial ones)!

🚨New paper out!🚨 Excited to share our study published in Science Translational Medicine. This 5yr project was led by Susan @dutcherlab.bsky.social and Steve Brody. We asked a simple question: why do some PCD patients develop more severe lung disease than others? 1/ www.science.org/doi/10.1126/...

We are now accepting applications for two PhD positions within the Cilia-AI PhD training network (cilia-ai.eu). Please apply via the link below. Application deadline March 15th, start date September 1st, 2025. employment.ku.dk/all-vacancies/…

Hmm… customs GIFs are not working yet it seems? So here is what we do in a movie!

Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel. Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.

Hot (and cold) microtubules👇🏼

From random gliding to ordered patterns. The movie starts with microtubules gliding on a minus-end directed molecular motor. Then, @bhagyanaths.bsky.social added a plus-end directed motor (magenta) to induce this polarity sorting and ordering process. more details here: www.pnas.org/doi/10.1073/...

Prepping for Los Reyes (Three Kings Day) #2

Prepping for Los Reyes (Three Kings Day) #1

Very sad news today… Joan was director when I joined @IRBBarcelona.org and I owe him this great opportunity. He has led us to become not only a place for excellent science, but also a warm, friendly and collegial environment, a rare combination. We continue in Joan’s spirit, he will be missed!

Mahamid and Woodruff labs use cryo-ET to look at mitotic centrosomes: Stunned to see the pericentriolar matrix taking shape, and what seem to be ‚S size’ gamma-tubulin complex oligomers capping the end of 11-pf microtubules. www.cell.com/developmenta...

#IRBBarcelona rock band rocking the house at our holiday party!!! #irbholidayparty

We have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too! 👉 www.godinholab.com RT please 🙏🙏🙏👍👍

Yes!👇🏼

#Carnivorousplant #Heliamphora flowering time in the #terrarium, roughly following the flowering cycle in their native habitat for some reason.

📢 Dr. @direnaac.bsky.social receives an #ERCconsolidator Grant to study how #inflammation drives #PancreaticCancer. With €2M over the next 5 years, the IGNITE Project will dive deep into #PancreaticCancer to tackle early diagnosis & the development of more efficient treatments. ➡️ bit.ly/3CZCqj9 🧪

Retreat with my colleagues of the Mechanisms of Disease Programme @irbbarcelona.bsky.social ! Two days of discussing our research projects, enjoying good food, and concluding with a hike on a beautiful November day!

This is fun: A word cloud from my Google Scholar profile Use scholargoggler.com by @morinryan.bsky.social to make your own It comes complete with alt-text!

More than 40 @natureportfolio.bsky.social papers on the Human Cell Atlas.. Biology is changing so fast.. www.humancellatlas.org

Yes!!!