DLBCLone: A unified framework for neighbourhood-based genetic subtyping of lymphomas https://www.medrxiv.org/content/10.1101/2025.09.18.25335809v1

Team Lymphomania (students/staff of the Morin Lab) is doing the Terry Fox Run as usual. We each dedicate our time to uncovering molecular causes of lymphoma, building paths to better treatments.🏃‍♂️🧬 🙏 We are grateful for your support run.terryfox.ca/team/lymphom... #TerryFoxRun #LymphomaResearch

every. time.

Post your favourite Doctor Who. Wrong answers only

@dgermain21.bsky.social - fantastic work on LymphomaMAPs (microenv of DLBCL) looking at prognosis of CAR-T therapy. Showed that TEX archetype associated with signif worse outcome. Assoc with • exhausted T-cells • super-activated macrophages. #ICML18

Vaccines have literally saved more than 150 million lives over the last 50 years and prevented much more morbidity but hold up guys somebody with a brain worm knows better

Excited to report our Blood Cancer Discovery @theaacr.bsky.social article showing how DNA #methylation in #Burkitt #Lymphoma #BL impacts clinical outcome. Team effort co-led by @morinryan.bsky.social @sfu.ca group and our lab at @carrerasijc.bsky.social @ub.edu aacrjournals.org/bloodcancerd...

The Human Genome Project cost taxpayers $3 Billion. Two decades on, it has generated a staggering return on investment of $1 Trillion, with benefits in medicine, agriculture, energy, the environment, & more. If you want to boost the economy, funding science is one of the best things you could do.

Lungfish xkcd.com/3064

In 2024, sandbox.bio had >170,000 tutorial page views! 🥳 The most popular tutorials were: 1. ​Terminal basics 2. ​Genomic intervals with bedtools 3. ​Terminal exercises 4. ​Data exploration with awk 5. ​DNA sequencing QC Check them out here: sandbox.bio/tutorials

Justin Trudeau gave the exact kind of press conference today that we have been waiting for from our Democratic leaders. Watch it and learn from it. No gimmicks, no stunts, no script, no platitudes, no slogans, no games. Just straight talk, honesty, sincerity and facts.

I’m somehow on a Heritage Foundation mailing list (😂) and they sent a survey to see what we think of DOGE. Who wants to offer some m-fing feedback?!? secured.heritage.org/the-heritage... Please share with a friend or a thousand :)

Tomorrow is #RareDiseaseDay! Did you know that a disease is considered rare when it affects fewer than 1 in 2,000 people? But with 7,000+ rare diseases worldwide, they collectively affect 300M+ people. Support the ASH Research Awards Fund 🔗 https://bit.ly/3XjCFNr#RareDiseaseDay! #hematology #HemeSky #BloodSky

"valr provides tools to read and manipulate genome intervals and signals, similar to the BEDtools suite." I wonder if they considered naming it bedRtools? rnabioco.github.io/valr/

Get in dorks, we're going protesting! STAND UP FOR SCIENCE WITH US ON MARCH 7TH, 2025 WASHINGTON DC AND EVERY STATE CAPITOL Because science is for everyone! Find us at www.standupforscience2025.org #standupforscience2025 #scienceforall #sciencenotsilence

If you are an NIH or CDC scientist that lost your job, we have a home for you at UTHealth. I’m hiring physician scientists and we also have transplant ID fellowship slots open. Contact me. #IDSky #MedSky

Happy #FlagDay from ScholarGoggler scholargoggler.com

Remember that Europe (@ebi.embl.org) has mirrored all these services and they will keep on running. They look and feel a bit different but do the same thing. I think @ewanbirney.bsky.social should be able to confirm. www.europepmc.org www.ebi.ac.uk/jdispatcher/...

Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm https://academic.oup.com/bib/article/26/1/bbaf042/8002975 🧬🖥️🧪 https://github.com/Rozen-Lab/sig_attribution_paper_code

Looks like a bunch of people are trying to make a back-up before it's too late!

beyond reckless! "(staff) hoping to prevent as much damage as possible — [...] avoiding crashes or a system-wide breakdown caused by rapidly pushing new code into production with a limited knowledge of the system and its dependencies across the federal government"

Delighted to share our latest paper describing a method to read the levels of hundreds of metabolites or drugs in parallel using DNA sequencing. This method, which we call ‘smol-seq’ (Small MOLecule sequencing), harnesses the power of DNA sequencing for metabolite detection: rdcu.be/d8xLv (1/6)

Does anyone happen to have a backup of PubMed, just in case? How about dbGaP? Genomic Data Commons? 😬

Bruce MacKinnon, the editorial cartoonist at the Halifax Chronicle-Herald, drew this last November. No newspaper would print it. It now deserves an outing.

The Google Scholar PDF Reader extension has always shown an outline, makes references clickable/linked to GScholar (screenshot 1). Now it provides an AI summary of each section (screenshot 2). https://chromewebstore.google.com/detail/google-scholar-pdf-reader/dahenjhkoodjbpjheillcadbppiidmhp?hl=en

The "kitchen sink" of omics to solve the basis for an undiagnosed disease: long read genome , transcriptome, methytome, epigenome, all synchronized (a first) www.nature.com/articles/s41...

American science and medicine has been thrown into chaos and uncertainty over the past week. Here are some stories to get up to speed. 1/12

Our new review from @morinryan.bsky.social's lab details the recurrence and confidence of mutated genes in B cell lymphomas. ashpublications.org/bloodadvance...

How many, and which, genes are recurrently affected by somatic mutations in Burkitt lymphoma? DLBCL? FL? Our "Audit of B-cell Cancer Genes" attempts to answer this question. tinyurl.com/llmppabcg

As I am new to this place, I thought I might introduce my research interests with a word cloud made with Scholar Goggler 🥽 @scholargoggler.bsky.social. If you are working on this stuff too, please like ♥️ this post so I can follow you back!

Very nice review on our current understanding of the genetic and molecular underpinnings of Burkitt lymphoma www.sciencedirect.com/science/arti...

A genomic study on Follicular lymphoma (FL) in today's issue of Blood provides a foundation that will hopefully lead to new therapies for patients who are unlikely to benefit long-term from standard-of-care. I'll explain how: #bloodsky

My Tidyverse local synteny visualizer is up on GitHub: github.com/cxli233/Tidy... GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.

Not sure who made this & when but fittingly came across it in my downloads folder today:

Did #ASH2024 delegates collectively take down the server in an unintentional ddos attack?

Jasper Wong, a PhD student working in both the Scott and Morin labs, will be presenting his work on the genetics and microenvironment of plasmablastic lymphoma this Saturday at #ASH2024 ash.confex.com/ash/2024/web...

Haya Shaalan, a recent graduate from the Morin lab, will be presenting her work on FL genetic classification in the Single-cell and Spatial Analyses in Indolent Lymphomas session at #ASH2024 See some of you there! ash.confex.com/ash/2024/web...

Looking forward to meeting some of you at the ASH-a-Palooza Blood Buddies speed-mentoring session on Friday. I have a friendly competition with a colleague who is also mentoring. If there are spots available, sign up to hang out with me (and definitely not anyone else)! #ASH2024

Scholargoggler.com 👇 nailed it

This one reminds me of the monochrome CRT display on my old Tandy 1000

We recently announced a dual new release of intOGen and boostDM Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations ➡️ Compendium of Cancer Driver Genes - www.intogen.org ➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm

Started a hemostasis & thrombosis starter pack but I know I’m missing a bunch of accounts. Let me know who else to add! go.bsky.app/4reAetF

Point taken scholargoggler.com, I became a little too obsessed with #perovskite structured materials #ChemSky

It’s nice to see the community is not just normalizing but embracing self-goggling

🧪Putting this epic tenure-track job posting into the #science feed. Great community, fantastic resources, give @rodallab.bsky.social a shoutout if this is up your alley!

The internet is a magical place sometimes. Thanks scholargoggler.com

SkyStats is neat. I like the word cloud it generates from recent posts. skystats.mariozechner.at

Just got this update from my lab. 🧪 Freezer door wasn't properly closed for... weeks maybe? This is gonna be a process 😳