this is why i use "predictive model" and ask "what does it predict?" they used a tool that predicts whether an "amino acid in a protein is likely to contact whatever chemicals that structure can bind" and one that "predicts whether any given protein is likely to form a stable structure"

ICE deportation agent: “Just to be upfront, the goal is to put as many guns and badges out in the field as possible.”

This morning, Ms. Rachel and I visited District 2 Pre-K Center, where we sang and read with the wonderful students and educators. We also discussed universal childcare - and how we're making it happen for NYC!

When in doubt, aurora borealis!

My new year's resolution this year, as every year, is to be a more available, supportive friend as well as an increasingly looming, formidable enemy.

If you’re an indie artist working with a small, indie label, they usually handle digital distribution and don’t give you much of a choice in the matter. Depending on how “indie” you are, you may not have the leverage to push back against it.

As Ahmed Al Ahmed so clearly showed, when Republicans target and threaten Muslims simply for being Muslim, they abandon our core values and fuel hate and violence. This dangerous and baseless Islamophobia has no place in our country, particularly from our elected leaders.

"When same-sex marriage was still years away, there was America’s Uncle, straight as can be, demanding a future in which LGBTQ families be given a full stake in the American Dream and hurry the fuck up on that, please and thank you." charlotteclymer.substack.com/p/americas-u...

There’s a whole thing in Hanukah about how you’re supposed to “publicize the miracle” except that there are all sorts of exceptions in times of danger. Because the times that the Jews have lived under have not always been safe. May the souls of the murdered in Australia be for a blessing.

Extraordinary courage from Ahmed al Ahmed, a Muslim, 43-year-old father of two, who bravely risked his life to save his neighbors celebrating Hanukkah. Praying for his full & speedy recovery. And so deeply inspired by his example.

Oh you asked ChatGPT? Yeah well I told the wind and it just sighed.

Sohla is a queen. What if we didn't do this?!?

it's wild how the positive use cases are like "save 5 minutes reading a long doc" and "write a generic email faster" and the negative use cases are "get encouraged to dive deeper in psychosis, misogyny, or suicidal thoughts" and we're still on the fence about overall value

He said that software teams who were using AI coding tools were “45% more efficient” than those who didn’t. How was that calculated? Lines of code? Tickets completed? Actual products released to customers? Metrics are only useful if we know what they mean!

My hot take is: “cancel culture” simultaneously does too much and not enough. It angers people who want to be able to say whatever they want with impunity, and it doesn’t allow for actual accountability. There is no room for improvement, meaningful consequences, or reconciling with one’s actions.

evergreen

One of my uncles made a very rude and gross joke at my expense at a holiday dinner, that was overheard by another uncle and and a few male cousins, and not one person told him he was being an ass.

This makes me deeply sad but also 1000% doesn't surprise me. We northerners reeeeeally have to stop thinking that the South has the market cornered on racism.

I’m most of the way through The AI Con by @emilymbender.bsky.social and @alexhanna.bsky.social and for me the central thesis is that our entire economic system is based on a broken incentive structures where the goal is not to Do Good Work (cont)

Yet another reason why measuring the success of AI coding tools as “lines of code committed to production systems” is a poor metric. As a senior engineer, some of my most important work is knowing what code *not* to write.

The purpose of a system is what it does, etc.

Here's one of the main reasons why I'm 100% sure AI is in a bubble, regardless of any potential "success" it has in the next 6-12 months. Right now the majority of AI "success" at scale has been found in AI coding tools for software engineers. (thread)

Democrats, coming off a historic national protest against fascism and a country-wide electoral sweep:

I know NYT changes these headlines up now and then but.... 🥴 AM -> PM

I have received more pushback and antisemitism from Democrats telling me I'm a Bad Jew and have Betrayed My People for opposing the genocide than any other group

why is this mayoral election different than all other mayoral elections? in all other mayoral elections, we get to see andrew cuomo lose but once. but in this mayoral elections, we get to see him lose *twice*.

Framing this as part of the discussion about the cost of higher education in terms of ROI makes this even more salient. 🧵

The president is spending quite a bit of time on renovations to public property he personally uses while millions are about to lose food assistance and the government is shut down.

Tomorrow, SNAP benefits are set to expire. In Boston, if you need assistance with groceries or paying the bills, or if you’re looking to donate to our support fund with @bostonfdn.bsky.social, please visit boston.gov/snap or dial 311 to get help.

This has the vibe of the fox going to the farmer to tell them that the security at the henhouse is "completely out of control"

I know I'm just screaming into the void but if you manage product in any capacity and you make an optional change such that customer data is LESS private/secure, please allow folks to OPT IN instead of OPT OUT. Customers shouldn't have to constantly be on alert for their apps to screw them, and yet.

One of the greats!

If I were running the DNC, there would be Democratic Party sponsored food relief banks across the country right now that specifically welcomed anyone regardless of party affiliation. Along with the food, there could be voter registration and links to runforsomething.net

Who wants to bet that SBF is next?

I'm not ready for this.

If anyone needs me I will be in the museum, lying down next to the bog bodies.

Yes It's deeply racist and antisemitic at the same time I wish it were necessary not to have to say this but also, it's not just JD Vance, I see it on the left all the time. If you are not Jewish you do not get to be the arbiter of who is and is not a (good) Jew.

just met a woman at a party & asked her what she did for work. could barely understand her because she was so soft spoken & had an accent so i just nodded a bunch. “she’s in culture,” her friend said. i finally realised that i was talking to ANNA DELVEY I ASKED ANNA DELVEY WHAT SHE DID FOR WORK

twice a year the entire U.S. press becomes a marketing extension of a single billionaire-owned retailer, and nobody in any position of editorial power thinks it's weird or gross

Sorry but you actually can’t hold me accountable because the computer did all that bad stuff. Unrelated, the computer is now alive.

Damn. This is amazing. £325 per week, paid monthly, for 3 years - and the result was a profit for the Irish economy: www.citizensinformation.ie/en/employmen...

What the fuck do you mean I got a longer prison sentence than Diddy

Happening now: Hundreds of rabbis and Jewish community members gather in Brooklyn for a mass public memorial service on Yom Kippur, demanding a permanent ceasefire in Gaza and for the U.S. to stop arming Israel.

They're human beings in need of medical care and you're a Catholic

To anyone disabled, pregnant, prone to eating disorders, blood sugar issues, on meds that require food etc: Yom Kippur rules are very clear. You must NOT fast if it will hurt your health. Don’t believe me? Believe Chabad, even they say so. Judaism doesn’t want you to endanger your health.

I don't think we'll ever get another sentence which sums up everything the New York Times embodies quite like "Some legal experts have called it a crime to summarily kill civilians".

🎶 Take a look, it's in a book 🎶 🥹 After nearly 20 years... Reading Rainbow is returning to motivate, help, and encourage kids to become avid readers with new episodes, new friends, new projects, and of course... new books! Make sure to follow the rainbow 📚🌈 #FollowTheRainbow